JohnCLieskeMD

Nephrology • Rochester, MN

Acute Renal Failure

Professor, Internal Medicine, Mayo Medical School

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Office
200 1st St Sw
Rochester, MN 55905
Phone+1 507-284-2511
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Education & Training

University of ChicagoFellowship, Nephrology, 1989 - 1993
Emory University School of MedicineResidency, Internal Medicine, 1986 - 1989
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1986

Certifications & Licensure

MN State Medical License 2000 - 2024
IL State Medical License 1989 - 2002
GA State Medical License 1988 - 1991
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Nephrology

Awards, Honors, & Recognition

Fellow (FACP) American College of Physicians, 2002
Fellow (ASNF) American Society of Nephrology

Clinical Trials

Use of Oral Probiotics to Reduce Urinary Oxalate Excretion Start of enrollment: 2006 Feb 01
Completed
Phase 1, Phase 2
Rare Kidney Stone Consortium Patient Registry Start of enrollment: 2003 Jul 01
Recruiting
International Registry for Primary Hyperoxaluria Start of enrollment: 2003 Sep 01
Withdrawn
Oxazyme in Patients With Hyperoxaluria Start of enrollment: 2010 May 01
Completed
Phase 1, Phase 2
Nephrotic Syndrome Study Network Start of enrollment: 2010 Apr 01
Recruiting
Dent Disease Mutation Genotyping Start of enrollment: 2012 Aug 01
Completed
Not Applicable
Role Of Phosphorus And FGF 23 In Patients With Dent Disease Start of enrollment: 2014 Sep 01
Completed
Phase 1, Phase 2
Review of Kidney Biopsies of Dent Disease Patients Start of enrollment: 2013 Oct 01
Completed
Use of Tolvaptan to Reduce Urinary Supersaturation: a Pilot Proof of Principle Study Start of enrollment: 2014 Mar 01
Completed
Phase 1
Prospective Research Rare Kidney Stones (ProRKS) Start of enrollment: 2016 May 01
Recruiting
Monogenic Kidney Stone - Genetic Testing Start of enrollment: 2017 Sep 11
Recruiting
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Publications & Presentations

PubMed

How We Treat Primary Hyperoxaluria Type 1.
Peter C Harris, Matthew C Breeggemann, John C Lieske, Gregory E Tasian, Kyle D Wood> ;Clinical Journal of the American Society of Nephrology. 2024 Mar 18
Clinicopathologic Characteristics, Etiologies, and Outcome of Secondary Oxalate Nephropathy.
Samih H Nasr, Anthony M Valeri, Samar M Said, Sanjeev Sethi, Karl A Nath, John C Lieske, Lihong Bu> ;Mayo Clinic Proceedings. 2024 Apr 1
3 citations
Mayo Clinic Consensus Report on Membranous Nephropathy: Proposal for a Novel Classification.
Sanjeev Sethi, Laurence H Beck Jr, Richard J Glassock, Mark Haas, An S De Vriese, Tiffany N Caza, Elion Hoxha, Gérard Lambeau, Nicola M Tomas, Benjamin Madden, Hanna D...> ;Mayo Clinic Proceedings. 2023 Nov 1
6 citations
Mayo Clinic consensus report on membranous nephropathy: proposal for a novel classification.
Sanjeev Sethi, Laurence H Beck Jr, Richard J Glassock, Mark Haas, An S De Vriese, Tiffany N Caza, Elion Hoxha, Gérard Lambeau, Nicola M Tomas, Benjamin Madden, Hanna D...> ;Kidney International. 2023 Dec 1
Successful Treatment of Primary Hyperoxaluria Type 2 with a Combined Liver and Kidney Transplant.
Kareem M Genena, David J Sas, Dawn S Milliner, John C Lieske> ;Kidney International Reports. 2023 Jul 1
1 citations
End Point Considerations for Clinical Trials in Enteric Hyperoxaluria.
Craig B Langman, Dean Assimos, Melanie Blank, Juan Calle, Andreas Grauer, Annamaria Kausz, Dawn Milliner, Lama Nazzal, Kimberly Smith, Greg Tasian, Aliza Thompson, Kyl...> ;Clinical Journal of the American Society of Nephrology. 2023 Dec 1
2 citations
The Site and Type ofGenetic Variation Impact the Resulting Dent Disease-1 Phenotype.
Muhammad G Arnous, Jennifer Arroyo, Andrea G Cogal, Franca Anglani, Hee Gyung Kang, David Sas, Peter C Harris, John C Lieske> ;Kidney International Reports. 2023 Jun 1
Authors' Reply: Urine Metabolomic Versus Standard Chemistry Analysis: What can Metabolomic Analysis Bring to the Treatment and Prevention of Urolithiasis?
Charat Thongprayoon, John C Lieske, Andrew D Rule, Aleksandar Denic> ;Journal of the American Society of Nephrology. 2023 Jun 1
1 citations
Outpatient Antibiotic Use is Not Associated with an Increased Risk of First-Time Symptomatic Kidney Stones.
Charat Thongprayoon, Lisa E Vaughan, Erin F Barreto, Ramila A Mehta, Kevin Koo, Phillip J Schulte, John C Lieske, Andrew D Rule> ;Journal of the American Society of Nephrology. 2023 Aug 1
Reply by Authors.
Cameron J Britton, Vidit Sharma, Christine M Lohse, R Houston Thompson, John C Lieske, Andrew D Rule, Aaron M Potretzke> ;Urology Practice. 2023 May 1
1 citations
Non-race-based Glomerular Filtration Rates to Estimate Renal Functional Outcomes Following Radical and Partial Nephrectomy.
Cameron J Britton, Vidit Sharma, Christine M Lohse, R Houston Thompson, John C Lieske, Andrew D Rule, Aaron M Potretzke> ;Urology Practice. 2023 May 1
8 citations
Mendelian Randomization: A Powerful Tool to Illuminate Pathophysiologic Mechanisms.
John C Lieske> ;Mayo Clinic Proceedings. 2023 Apr 1
1 citations
Characterization of Stone Events in Patients With Type 3 Primary Hyperoxaluria.
Muhammad G Arnous, Lisa Vaughan, Ramila A Mehta, Phillip J Schulte, John C Lieske, Dawn S Milliner> ;The Journal of Urology. 2023 Jun 1
Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate.
Jason N Barreto, Erin F Barreto, Kristin C Mara, Andrew D Rule, John C Lieske, Callen D Giesen, Carrie A Thompson, Nelson Leung, Thomas E Witzig, Kianoush B Kashani> ;Kidney360. 2023 May 1
10 citations
Precision nephrology identified tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis.
Laura H Mariani, Sean Eddy, Fadhl M AlAkwaa, Phillip J McCown, Jennifer L Harder, Viji Nair, Felix Eichinger, Sebastian Martini, Adebowale D Ademola, Vincent Boima, He...> ;Kidney International. 2023 Mar 1
Application of multivariate joint modeling of longitudinal biomarkers and time-to-event data to a rare kidney stone cohort.
Lisa E Vaughan, John C Lieske, Dawn S Milliner, Phillip J Schulte> ;Journal of Clinical and Translational Science. 2023 Jan 1
1 citations
Measuring copeptin, a surrogate for vasopressin in patients with hypertension - Can it identify those who are volume Responsive?
Ronstan Lobo, John C Lieske, Leslie J Donato, LaTonya J Hickson, David O Hodge, Arlene Chapman, Gary L Schwartz, Allan S Jaffe> ;Clinical Biochemistry. 2023 Feb 1
AUTHOR REPLY.
Cameron J Britton, Vidit Sharma, Christine M Lohse, John C Lieske, Paige E Nichols, Abhinav Khanna, John C Cheville, Stephen A Boorjian, Bradley C Leibovich, R Houston...> ;Urology. 2022 Nov 1
6 citations
Nuclear Magnetic Resonance Metabolomic Profiling and Urine Chemistries in Incident Kidney Stone Formers Compared with Controls.
Charat Thongprayoon, Ivan Vuckovic, Lisa E Vaughan, Slobodan Macura, Nicholas B Larson, Matthew R D'Costa, John C Lieske, Andrew D Rule, Aleksandar Denic> ;Journal of the American Society of Nephrology. 2022 Nov 1
GeoBioMed perspectives on kidney stone recurrence from the reactive surface area of SWL-derived particles.
Lauren G Todorov, Mayandi Sivaguru, Amy E Krambeck, Matthew S Lee, John C Lieske, Bruce W Fouke> ;Scientific Reports. 2022 Nov 1
1 citations
Dietary Assessment of Lithogenic Factors in Plant-Based Meat Products.
Christine W Liaw, Aaron M Potretzke, Jared S Winoker, Brian R Matlaga, John C Lieske, Kevin Koo> ;Journal of Endourology. 2023 Jan 1
2 citations
Differences of Uric Acid Transporters Carrying Extracellular Vesicles in the Urine from Uric Acid and Calcium Stone Formers and Non-Stone Formers.
Zhijian Lin, Muthuvel Jayachandran, Zejfa Haskic, Sanjay Kumar, John C Lieske> ;International Journal of Molecular Sciences. 2022 Sep 2
22 citations
PHYOX2: a pivotal randomized study of nedosiran in primary hyperoxaluria type 1 or 2.
Michelle A Baum, Craig Langman, Pierre Cochat, John C Lieske, Shabbir H Moochhala, Shuzo Hamamoto, Hiroyuki Satoh, Chebl Mourani, Gema Ariceta, Armando Torres, Martin ...> ;Kidney International. 2023 Jan 1
13 citations
Dietary Risk Factors for Incident and Recurrent Symptomatic Kidney Stones.
Api Chewcharat, Charat Thongprayoon, Lisa E Vaughan, Ramila A Mehta, Phillip J Schulte, Helen M O'Connor, John C Lieske, Eric N Taylor, Andrew D Rule> ;Mayo Clinic Proceedings. 2022 Aug 1
2 citations
Progression of Chronic Kidney Disease Following Radical and Partial Nephrectomy.
Cameron J Britton, Vidit Sharma, Christine M Lohse, John C Lieske, Paige E Nichols, Abhinav Khanna, John C Cheville, Stephen A Boorjian, Bradley C Leibovich, R Houston...> ;Urology. 2022 Nov 1
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Journal Articles

Genome-Wide Meta-Analysis of Macronutrient Intake of 91,114 European Ancestry Participants from the Cohorts for Heart and Aging Research in Genomic Epidemiology Consor...
Paul M Ridker, John C Lieske, Jerome I Rotter, Jose C Florez, D C Rao, Stephen T Turner, Nature

Lectures

Kidney Stone Disease: Take Care of That Rock
American Society of Nephrology Kidney Week 2019 - Washington, D.C. - 11/7/2019

Authored Content

Challenges in Measuring Glomerular Filtration Rate: A Clinical Laboratory PerspectiveFebruary 2018

Press Mentions

Diets High in Calcium and Potassium May Prevent Kidney StonesAugust 11th, 2022
Diets Higher in Calcium and Potassium May Help Prevent Recurrent Symptomatic Kidney Stones, Mayo Clinic Study FindsAugust 1st, 2022
Had a Kidney Stone? This Diet May Help Prevent AnotherFebruary 8th, 2022
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Grant Support

Kidney Disease Research Training ProgramNational Institute Of Diabetes And Digestive And Kidney Diseases2010–2011
Pilot And Feasibility ProgramNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2011
Defining The Natural History And Treatment Options For Dent DiseaseNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2011
Mayo Clinic Urology O'Brien Research CenterNational Institute Of Diabetes And Digestive And Kidney Diseases2008–2011
Genetic Determinants Of Urine LithogenicityNational Institute Of Diabetes And Digestive And Kidney Diseases2008–2011
Nephrolithiasis And Chronic Kidney DiseaseNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2007
Use Of Symbiotics To Reduce Urinary Oxalate ExcretionNational Center For Complementary &Alternative Medicine2005–2007
Role Of Nanobacteria In Human Calcifying DiseaseNational Institute Of Diabetes And Digestive And Kidney Diseases2004
Novel Inhibitor Of Crystal Adhesion To Renal CellsNational Institute Of Diabetes And Digestive And Kidney Diseases2004
Role Of Nanobacteria In Human Calcifying DiseaseNational Institute Of Diabetes And Digestive And Kidney Diseases2003
Oxalate-Induced Renal Scarring And Crystal RetentionNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2003
Novel Inhibitor Of Crystal Adhesion To Renal CellsNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2003
Novel Inhibitor Of Crystal Adhesion To Renal CellsNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2000
Urinary Crystal-Renal Cell Interactions In UrolithiasisNational Institute Of Diabetes And Digestive And Kidney Diseases1994–1998
Renal Epithelial Cell Growth Induced By Urinary CrystalsNational Institute Of Diabetes And Digestive And Kidney Diseases1991–1992