JohnP.MooreJr.MD

PubMed

• Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence.
  Sliepen, K.,Han, B. W.,Bontjer, I.,Mooij, P.,Garces, F.,Behrens, A. J.,Rantalainen, K.,Kumar, S.,Sarkar, A.,Brouwer, PJM.,Hua, Y.,Tolazzi, M.,Schermer, E.,Torres, J. L...> ;Nat Commun. 2019 May 31
• Optimizing the production and affinity purification of HIV-1 envelope glycoprotein SOSIP trimers from transiently transfected CHO cells.
  Cupo, A.,Cruz Portillo, V. M.,Gelfand, P.,Yasmeen, A.,Klasse, P. J.,Moore, J. P.> ;PLoS ONE. 2019 Apr 09
• Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes
  John Moore Jr., MD> ;Journal of Virology. 2018 Nov 30
• Developability assessment of physicochemical properties and stability profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 envelope glycoprotein trimers ...
  Whitaker, N.,Hickey, J. M.,Kaur, K.,Xiong, J.,Sawant, N.,Cupo, A.,Lee, W. H.,Ozorowski, G.,Medina-Ramírez, M.,Ward, A. B.,Sanders, R. W.,Moore, J. P.,Joshi, S. B.,Volk...> ;J Pharm Sci. 2019 Feb 19
• Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
  Kumar, S.,Sarkar, A.,Pugach, P.,Sanders, R. W.,Moore, J. P.,Ward, A. B.,Wilson, I. A.> ;Nat Commun. 2019 Feb 17
• Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen.
  Struwe, W. B.,Chertova, E.,Allen, J. D.,Seabright, G. E.,Watanabe, Y.,Harvey, D. J.,Medina-Ramirez, M.,Roser, J. D.,Smith, R.,Westcott, D.,Keele, B. F.,Bess, J. W.,San...> ;Cell Rep. 2018 Aug 23
• Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers in Vitro
  John Moore Jr., MD> ;mBio.
• Epitopes for Neutralizing Antibodies Induced by HIV-1 Envelope Glycoprotein BG505 SOSIP Trimers in Rabbits and Macaques
  John P Moore, Guido Silvestri> ;PLoS One. 2018 Feb 24
• Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages.
  Behrens, A. J.,Kumar, A.,Medina-Ramirez, M.,Cupo, A.,Marshall, K.,Cruz Portillo, V. M.,Harvey, D. J.,Ozorowski, G.,Zitzmann, N.,Wilson, I. A.,Ward, A. B.,Struwe, W. B....> ;J. Proteome Res.. 2018 Feb 09
• Immunogenicity in Rabbits of SOSIP Trimers from Clades A, B and C, Given Individually, Sequentially or in Combinations
  John Moore Jr., MD> ;mBio. 2018 Jan 26
• cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.
  Dey, A. K.,Cupo, A.,Ozorowski, G.,Sharma, V. K.,Behrens, A. J.,Go, E. P.,Ketas, T. J.,Yasmeen, A.,Klasse, P. J.,Sayeed, E.,Desaire, H.,Crispin, M.,Wilson, I. A.,Sander...> ;Biotechnol. Bioeng.. 2017 Nov 19
• Improving the expression and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers by targeted sequence changes.
  Ringe, R. P.,Ozorowski, G.,Yasmeen, A.,Cupo, A.,Cruz Portillo, V. M.,Pugach, P.,Golabek, M.,Rantalainen, K.,Holden, L. G.,Cottrell, C. A.,Wilson, I. A.,Sanders, R. W.,...> ;J. Virol.. 2017 Apr 07
• Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.
  Ringe, R. P.,Yasmeen, A.,Ozorowski, G.,Go, E. P.,Pritchard, L. K.,Guttman, M.,Ketas, T. A.,Cottrell, C. A.,Wilson, I. A.,Sanders, R. W.,Cupo, A.,Crispin, M.,Lee, K. K....> ;J. Virol.. 2015 Aug 28
• Short Communication: Virion Aggregation by Neutralizing and Nonneutralizing Antibodies to the HIV-1 Envelope Glycoprotein.
  Alexander, M. R.,Sanders, R. W.,Moore, J. P.,Klasse, P. J.> ;AIDS Res. Hum. Retroviruses. 2015 Jun 19
• Chemical Cross-linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens.
  Schiffner, T.,de Val, N.,Russell, R. A.,de Taeye, S. W.,Torrents de la Pena, A.,Ozorowski, G.,Kim, H. J.,Nieusma, T.,Brod, F.,Cupo, A.,Sanders, R. W.,Moore, J. P.,Ward...> ;J. Virol.. 2015 Oct 30
• A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo.
  Freund, N. T.,Horwitz, J. A.,Nogueira, L.,Sievers, S. A.,Scharf, L.,Scheid, J. F.,Gazumyan, A.,Liu, C.,Velinzon, K.,Goldenthal, A.,Sanders, R. W.,Moore, J. P.,Bjorkman...> ;PLoS Pathog.. 2015 Oct 31
• What do chaotrope-based avidity assays for antibodies to HIV-1 envelope glycoproteins measure?
  Alexander, M. R.,Ringe, R.,Sanders, R. W.,Voss, J. E.,Moore, J. P.,Klasse, P. J.> ;J. Virol.. 2015 Mar 27
• A pièce de resistance: how HIV-1 escapes small molecule CCR5 inhibitors.
  Moore, J. P.,Kuritzkes, D. R.> ;Curr Opin HIV AIDS. 2009 Apr 03
• AIDS/HIV. A STEP into darkness or light?
  Moore, J. P.,Klasse, P. J.,Dolan, M. J.,Ahuja, S. K.> ;Science. 2008 May 10
• HIV-1 pathogenesis: the complexities of the CCR5-CCL3L1 complex.
  Moore, J. P.,Klasse, P. J.> ;Cell Host Microbe. 2007 Nov 17
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