JohnnyWayneBryantMD

PubMed

• Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat.
  Peterson, J. T., Li, H., Dillon, L., Bryant, J. W.> ;Cardiovasc Res. 2000 May
• Butenolide endothelin antagonists with improved aqueous solubility.
  Patt, W. C., Cheng, X. M., Repine, J. T., Lee, C., Reisdorph, B. R., Massa, M. A., Doherty, A. M., Welch, K. M., Bryant, J. W., Flynn, M. A., Walker, D. M., Schroeder,...> ;J Med Chem. 1999 Jun 17
• The discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an orally efficacious fa...
  Kohrt, J. T., Bigge, C. F., Bryant, J. W., Casimiro-Garcia, A., Chi, L., Cody, W. L., Dahring, T., Dudley, D. A., Filipski, K. J., Haarer, S., Heemstra, R., Janiczek, ...> ;Chem Biol Drug Des. 2007 Aug
• Structure-based drug design of pyrrolidine-1, 2-dicarboxamides as a novel series of orally bioavailable factor Xa inhibitors.
  Van Huis, C. A., Bigge, C. F., Casimiro-Garcia, A., Cody, W. L., Dudley, D. A., Filipski, K. J., Heemstra, R. J., Kohrt, J. T., Narasimhan, L. S., Schaum, R. P., Zhang...> ;Chem Biol Drug Des. 2007 Jun
• The discovery of glycine and related amino acid-based factor Xa inhibitors.
  Kohrt, J. T., Filipski, K. J., Cody, W. L., Bigge, C. F., La, F., Welch, K., Dahring, T., Bryant, J. W., Leonard, D., Bolton, G., Narasimhan, L., Zhang, E., Peterson, ...> ;Bioorg Med Chem. 2006 Jul 1
• Benzyl ether structure-activity relationships in a series of ketopiperazine-based renin inhibitors.
  Powell, N. A., Clay, E. H., Holsworth, D. D., Bryant, J. W., Ryan, M. J., Jalaie, M., Edmunds, J. J.> ;Bioorg Med Chem Lett. 2005 Nov 1
• Equipotent activity in both enantiomers of a series of ketopiperazine-based renin inhibitors.
  Powell, N. A., Clay, E. H., Holsworth, D. D., Bryant, J. W., Ryan, M. J., Jalaie, M., Zhang, E., Edmunds, J. J.> ;Bioorg Med Chem Lett. 2005 May 2
• Discovery of novel non-peptidic ketopiperazine-based renin inhibitors.
  Holsworth, D. D., Powell, N. A., Downing, D. M., Cai, C., Cody, W. L., Ryan, J. M., Ostroski, R., Jalaie, M., Bryant, J. W., Edmunds, J. J.> ;Bioorg Med Chem. 2005 Apr 1
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