
Jonathan P.S. Knisely MD FRCP(C) relinquished; FASTRO
Benign Diseases, Central Nervous System Cancer
Professor of Radiation Oncology, Weill Cornell Medicine
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1283 York Avenue4th FloorNew York, NY 10065
Phone+1 212-746-3607
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Summary
- Dr. Jonathan Knisely is a radiation oncologist with special expertise in radiation management of benign and malignant central nervous system diseases. He attended Yale University, where he completed degree requirements in Molecular Biophysics and Biochemistry and East Asian Language and Literature (Chinese). Following medical school at the University of Pennsylvania, he completed a residency in Internal Medicine at Michael Reese Hospital and Medical Center and then completed a second residency in Radiation Oncology at the University of Toronto, training at Princess Margaret Hospital and Sunnybrook Health Sciences Center.
Dr. Knisely has held faculty positions in Radiation Oncology at Weill Cornell Medicine, Northwell Health/Hofstra University and the Yale University School of Medicine. At all of these academic medical centers he led their stereotactic radiosurgery and image-guided radiation therapy programs. He introduced automated rigid 3D image registration to radiation oncology, which is a fundamental contribution to present-day image-guided radiation therapy. He has over 150 peer-reviewed publications on subjects largely focused on brain cancer and stereotactic radiosurgery and has edited several textbooks and written numerous chapters on these subjects.
Dr. Knisely has been recognized multiple times as one of America's Top Doctors and for his work in cancer treatment. He has served on the editorial boards of numerous leading medical journals, including the Journal of Clinical Oncology, the Journal of Neuro-Oncology, the International Journal of Radiation Oncology, Biology, Physics and Neurosurgery. He is now on the faculty of the University of Amsterdam's Department of Radiation Oncology.
Clinical Expertise
- Stereotactic radiosurgery, Intensity-modulated radiation therapy, Radiosurgery, Stereotactic body radiotherapy, Brain cancer, Brain tumor radiotherapy
Education & Training
Michael Reese Hospital/University of Illinois College of Medicine at ChicagoResidency, Internal Medicine, 1986 - 1989
Perelman School of Medicine at the University of PennsylvaniaClass of 1986
Certifications & Licensure
FL State Medical License 2022 - Present
NY State Medical License 2011 - 2026
CT State Medical License 1992 - 2013
IL State Medical License 1986 - 1989
American Board of Internal Medicine Internal Medicine
American Board of Radiology Radiation Oncology
Awards, Honors, & Recognition
- America's Top Doctors Castle Connolly, 2008-2011, 2013-2021
- America's Top Doctors for Cancer Castle Connolly, 2005-2010, 2012-2013, 2016-2021
- FASTRO Fellow, American Society for Radiation Oncology, 2017
Publications & Presentations
PubMed
- [Ga]-DOTATATE PET Standardized Uptake Value Reduction after Bevacizumab in High-grade Meningioma: A Potential Treatment Response Biomarker.Kellen Vo Vu, Hannah G Otis, Andrew Brandmaier, Joseph R Osborne, Philip E Stieg
AJNR. American Journal of Neuroradiology. 2026-09-02 - Yttrium-90 radioembolization for treatment of anaplastic meningioma liver metastases.Mohammad-Kasim Fassia, Arsalan Haghdel, Fred Pelzman, Rajiv Magge, Susan Pannullo
Radiology Case Reports. 2026-02-01 - 6 citationsBrain Imaging Surveillance for Patients With Metastatic Breast Cancer: A Randomized Clinical Trial Is Required to Guide Practice.Katarzyna J Jerzak, Ellen Warner, Jonathan P S Knisely, Arjun Sahgal
Journal of Clinical Oncology. 2025-10-10
Press Mentions
Some Brain Cancer Patients Have Radiation Options: StudyJuly 26th, 2016
Grant Support
- Somatostatin Receptor 2 Expression in Pituitary Neuroendocrine Tumors as a Basis for PET/MRI guided Subtype Stratification and Radiotherapy PlanningWEILL MEDICAL COLL OF CORNELL UNIV2025–2027
Professional Memberships
- American Radium SocietyMember
- Radiosurgery SocietyMember
- Member
Other Languages
- Chinese (Mandarin)
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