JonathanJamesKnowltonMDPhD

PubMed

• 20 citations
  Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network.
  Jonathan J. Knowlton, Daniel R. Gestaut, Boxue Ma, Gwen M. Taylor, Alpay B. Seven, Alexander Leitner, Gregory J. Wilson, Sreejesh Shanker, Nathan A. Yates, B. V. Venka...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Mar 16
• 7 citations
  Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase and Solute Carrier Family 35 Member A1 Are Required for Reovirus Binding and Infection.
  Kelly Urbanek, Danica M. Sutherland, Robert C. Orchard, Craig B. Wilen, Jonathan J. Knowlton, Pavithra Aravamudhan, Gwen M. Taylor, Herbert W. Virgin, Terence S. Dermody> ;Journal of Virology. 2020 Dec 22
• 25 citations
  A modified lysosomal organelle mediates nonlytic egress of reovirus
  Isabel Fernández de Castro, Raquel Tenorio, Paula Ortega-González, Jonathan J. Knowlton, Paula F. Zamora, Christopher H Lee, José J. Fernández, Terence S. Dermody, Cri...> ;The Journal of Cell Biology. 2020 Jul 6
• 23 citations
  Function, Architecture, and Biogenesis of Reovirus Replication Neoorganelles
  Raquel Tenorio, Isabel Fernández de Castro, Jonathan J. Knowlton, Paloma F. Zamora, Danica M. Sutherland, Cristina Risco, Terence S. Dermody> ;Viruses. 2019 Mar 21
• 37 citations
  Reovirus σNS and μNS Proteins Remodel the Endoplasmic Reticulum to Build Replication Neo-Organelles
  Raquel Tenorio, Isabel Fernández de Castro, Jonathan J. Knowlton, Paula F. Zamora, Christopher H Lee, Bernardo A. Mainou, Terence S. Dermody, Cristina Risco> ;Mbio. 2018 Aug 7
• 8 citations
  Murine cytomegalovirus M72 promotes acute virus replication in vivo and is a substrate of the TRiC/CCT complex.
  Sandhya Gopal, Encarnacion Perez Jr, Amanda Y. Xia, Jonathan J. Knowlton, Filipe Cerqueira, Terence S. Dermody, Jason W. Upton> ;Virology. 2018 Sep 1
• 14 citations
  Reovirus Nonstructural Protein σNS Acts as an RNA Stability Factor Promoting Viral Genome Replication.
  Paula F. Zamora, Liya Hu, Jonathan J. Knowlton, Roni M. Lahr, Rodolfo Moreno, Andrea J. Berman, B. V. Venkataram Prasad, Terence S. Dermody> ;Journal of Virology. 2018 Jul 17
• 36 citations
  The TRiC chaperonin controls reovirus replication through outer-capsid folding.
  Jonathan J. Knowlton, Isabel Fernández de Castro, Alison W. Ashbrook, Daniel R. Gestaut, Paula F. Zamora, Joshua A. Bauer, J. Craig Forrest, Judith Frydman, Cristina R...> ;Nature Microbiology. 2018 Mar 12
• 201 citations
  Nuclear translation visualized by ribosome-bound nascent chain puromycylation
  Alexandre David, Brian P. Dolan, Heather D. Hickman, Jonathan J. Knowlton, Giovanna Clavarino, Philippe Pierre, Jack R. Bennink, Jonathan W. Yewdell> ;The Journal of Cell Biology. 2012 Apr 2
• 38 citations
  Apoptosis Induced by Mammalian Reovirus Is Beta Interferon (IFN) Independent and Enhanced by IFN Regulatory Factor 3- and NF-κB-Dependent Expression of Noxa
  Jonathan J. Knowlton, Terence S. Dermody, Geoffrey H. Holm> ;Journal of Virology. 2012 Feb 1
• 34 citations
  RNA Polymerase II Inhibitors Dissociate Antigenic Peptide Generation from Normal Viral Protein Synthesis: A Role for Nuclear Translation in Defective Ribosomal Product...
  Brian P. Dolan, Jonathan J. Knowlton, Alexandre David, Jack R. Bennink, Jonathan W. Yewdell> ;Journal of Immunology. 2010 Dec 1
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Journal Articles

• Reovirus σNS and μNS Proteins Remodel the Endoplasmic Reticulum to Build Replication Neo-Organelles  
  Terence S. Dermody, Jonathan J. Knowlton, mBio