JonathanJosephLyonsMD

PubMed

• High burden of clonal mast cell disorders and hereditary α-tryptasemia in patients who need Hymenoptera venom immunotherapy.
  Peter Korošec, Gunter J Sturm, Jonathan J Lyons, Tinkara Pirc Marolt, Manca Svetina, Mitja Košnik, Mihaela Zidarn, Mark Kačar, Nina Frelih, Nika Lalek, Ajda Demšar Luz...> ;Allergy. 2024 Mar 13
• Alpha-Tryptase as a Risk-Modifying Factor for Mast Cell-Mediated Reactions.
  Hannah Shin, Jonathan J Lyons> ;Current Allergy and Asthma Reports. 2024 Apr 1
• A randomized double-blinded trial to assess recurrence of systemic allergic reactions following COVID-19 mRNA vaccination.
  Muhammad B Khalid, Ellen Zektser, Eric Chu, Min Li, Joanna Utoh, Patrick Ryan, Hanna S Loving, Roa Harb, Robbie Kattappuram, Lindsay Chatman, Stella Hartono, Estefania...> ;The Journal of Allergy and Clinical Immunology. 2024 Mar 7
• 1 citations
  Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome.
  Walitt, B., Singh, K., LaMunion, S., Hallett, M., Jacobson, S., Chen, K., Enose-Akahata, Y., Apps, R., Barb, J., Bedard, P., Brychta, R., Buckley, A., Burbelo, P., Cal...> ;Nature Communications. 2024 Feb 21
• Hereditary alpha-tryptasemia in patients with postural orthostatic tachycardia syndrome.
  Jenny Huang, Kamran Imam, Jose R Criado, Kathleen T Luskin, Yihui Liu, Leah H Puglisi, Jonathan J Lyons, Andrew A White> ;The Journal of Allergy and Clinical Immunology. in Practice. 2024 Feb 1
• 5 citations
  The Normal Range of Baseline Tryptase Should Be 1 to 15 ng/mL and Covers Healthy Individuals With HαT.
  Peter Valent, Gregor Hoermann, Patrizia Bonadonna, Karin Hartmann, Wolfgang R Sperr, Sigurd Broesby-Olsen, Knut Brockow, Marek Niedoszytko, Olivier Hermine, Yannick Ch...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 Oct 1
• 5 citations
  Severe food allergy reactions are associated with α-tryptase.
  Abigail Lang, Stephanie Kubala, Megan C Grieco, Allyson Mateja, Jacqueline Pongracic, Yihui Liu, Pamela A Frischmeyer-Guerrerio, Rajesh Kumar, Jonathan J Lyons> ;The Journal of Allergy and Clinical Immunology. 2023 Oct 1
• 2 citations
  Challenges in applying diagnostic criteria for systemic mastocytosis.
  Nathan A Boggs, Xiaoping Sun, Jonathan J Lyons, Jeremy C McMurray, David M Rose, Eric M Pryor, Dean D Metcalfe, Irina Maric> ;Blood Advances. 2023 Jul 11
• 3 citations
  Genetic Variants Leading to Urticaria and Angioedema and Associated Biomarkers.
  Jonathan J Lyons, Henriette Farkas, Anastasios E Germenis, Matija Rijavec, Tukisa D Smith, Peter Valent> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 Aug 1
• 10 citations
  Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms.
  Jack Chovanec, Ilker Tunc, Jason Hughes, Joseph Halstead, Allyson Mateja, Yihui Liu, Michael P O'Connell, Jiwon Kim, Young Hwan Park, Qinlu Wang, Quang Le, Mehdi Piroo...> ;Blood Advances. 2023 May 9
• 22 citations
  Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease.
  Mehul Sharma, Daniel Leung, Mana Momenilandi, Lauren C W Jones, Lucia Pacillo, Alyssa E James, Jill R Murrell, Selket Delafontaine, Jesmeen Maimaris, Maryam Vaseghi-Sh...> ;The Journal of Experimental Medicine. 2023 May 1
• Chromosomal microarray analysis supplements exome sequencing to diagnose children with suspected inborn errors of immunity.
  Breanna J Beers, Morgan N Similuk, Rajarshi Ghosh, Bryce A Seifert, Leila Jamal, Michael Kamen, Michael R Setzer, Colleen Jodarski, Rylee Duncan, Devin Hunt, Madison M...> ;Frontiers in Immunology. 2023 Jan 1
• 4 citations
  HαT is associated with increased risk for severe Hymenoptera venom-triggered anaphylaxis.
  Julij Šelb, Matija Rijavec, Peter Kopač, Jonathan J Lyons, Peter Korošec> ;The Journal of Allergy and Clinical Immunology. 2023 Mar 1
• 10 citations
  Clinical exome sequencing of 1000 families with complex immune phenotypes: Toward comprehensive genomic evaluations.
  Myles, I. A., Morgan N Similuk, Jia Yan, Rajarshi Ghosh, Andrew J Oler, Luis M Franco, Michael R Setzer, Michael Kamen, Colleen Jodarski, Thomas DiMaggio, Joie Davis, ...> ;The Journal of Allergy and Clinical Immunology. 2022 Oct 1
• 10 citations
  Proposed European Competence Network on Mastocytosis-American Initiative in Mast Cell Diseases (ECNM-AIM) Response Criteria in Advanced Systemic Mastocytosis.
  Jason Gotlib, Juliana Schwaab, William Shomali, Tracy I George, Deepti H Radia, Mariana Castells, Melody C Carter, Karin Hartmann, Ivan Álvarez-Twose, Knut Brockow, Pa...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Aug 1
• 5 citations
  Standards of Pathology in the Diagnosis of Systemic Mastocytosis: Recommendations of the EU-US Cooperative Group.
  Karl Sotlar, Tracy I George, Philip Kluin, Andreas Reiter, Juliana Schwaab, Jens Panse, Knut Brockow, Karin Hartmann, Wolfgang R Sperr, Thomas Kristensen, Boguslaw Ned...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Aug 1
• 9 citations
  Refined Treatment Response Criteria for Indolent Systemic Mastocytosis Proposed by the ECNM-AIM Consortium.
  Polina Pyatilova, Cem Akin, Iván Alvarez-Twose, Michel Arock, Patrizia Bonadonna, Knut Brockow, Joseph H Butterfield, Sigurd Broesby-Olsen, Melody C Carter, Mariana Ca...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Aug 1
• 25 citations
  Global Classification of Mast Cell Activation Disorders: An ICD-10-CM-Adjusted Proposal of the ECNM-AIM Consortium.
  Peter Valent, Karin Hartmann, Patrizia Bonadonna, Theo Gülen, Knut Brockow, Ivan Alvarez-Twose, Olivier Hermine, Marek Niedoszytko, Melody C Carter, Gregor Hoermann, J...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Aug 1
• 11 citations
  Incorporating Tryptase Genotyping Into the Workup and Diagnosis of Mast Cell Diseases and Reactions.
  Jonathan J Lyons, Georg Greiner, Gregor Hoermann, Dean D Metcalfe> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Aug 1
• 3 citations
  Resolving the genetics of human tryptases: implications for health, disease, and clinical use as a biomarker.
  Michael P O'Connell, Jonathan J Lyons> ;Current Opinion in Allergy and Clinical Immunology. 2022 Apr 1
• 15 citations
  Standards of Genetic Testing in the Diagnosis and Prognostication of Systemic Mastocytosis in 2022: Recommendations of the EU-US Cooperative Group.
  Gregor Hoermann, Karl Sotlar, Mohamad Jawhar, Thomas Kristensen, Guillaume Bachelot, Boguslaw Nedoszytko, Melody C Carter, Hans-Peter Horny, Patrizia Bonadonna, Wolfga...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Aug 1
• 3 citations
  Hereditary alpha-tryptasemia modifies clinical phenotypes among individuals with congenital hypermobility disorders.
  Maribel Vazquez, Jack Chovanec, Jiwon Kim, Thomas DiMaggio, Joshua D Milner, Clair A Francomano, Christina A Gurnett, Marco Ritelli, Marina Colombi, Jonathan J Lyons> ;HGG Advances. 2022 Apr 14
• 5 citations
  Targeted IL-4Rα blockade ameliorates refractory allergic eosinophilic inflammation in a patient with dysregulated TGF-β signaling due to ERBIN deficiency.
  H Richard Droghini, J Pablo Abonia, Margaret H Collins, Joshua D Milner, Jonathan J Lyons, Alexandra F Freeman, Vincent A Mukkada, Kimberly A Risma, Marc E Rothenberg,...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Jul 1
• 10 citations
  Elevated Basal Serum Tryptase: Disease Distribution and Variability in a Regional Health System.
  Aubri M Waters, Hyun J Park, Andrew L Weskamp, Allyson Mateja, Megan E Kachur, Jonathan J Lyons, Benjamin J Rosen, Boggs, N.> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 Sep 1
• 1 citations
  Hereditary alpha-tryptasemia despite normal tryptase-encoding gene copy number owing to copy number loss in trans.
  Sarah C Glover, Alexander Carlyle, Jonathan J Lyons> ;Annals of Allergy, Asthma & Immunology. 2022 Apr 1
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