Jonathan Gibson Stine MD MSc, FACP
Hepatology & Liver Transplantation
Associate Professor of Medicine and Public Health Sciences Penn State Health Liver Center Research Director
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500 University DrPenn State UniversityHershey, PA 17033
Phone+1 717-531-1017
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Summary
- Dr. Jonathan Stine is an internationally recognized liver expert with a research and clinical focus on nonalcoholic fatty liver disease (NAFLD) and exercise. He has authored more than 80 peer-reviewed papers, including multinational consensus guidelines, and several book chapters. Stine is the recipient of multiple research grants and awards from the American Association for the Study of Liver Diseases, American Cancer Society and National Institutes of Health. He has been a study investigator on over 20 NAFLD clinical trials and is on the editorial board for several leading hepatology journals. Dr. Stine is the NAFLD consultant to the American College of Sports Medicine’s Exercise is Medicine initiative. He is also a member of the Global Liver Institute’s NASH and Lifestyle councils. In addition to his scholarly work, Dr. Stine is a transplant hepatologist at Penn State Health Milton S. Hershey Medical Center and research director for Penn State Health Liver Center.
Education & Training
University of Virginia Medical CenterFellowship, Transplant Hepatology, 2016 - 2017- University of Virginia Medical CenterFellowship, Gastroenterology, 2013 - 2016
University of VirginiaMSc, Clinical Research, 2014 - 2015
MedStar Health Georgetown University/Georgetown HospitalChief Residency, Internal Medicine, 2012 - 2013- MedStar Health Georgetown University/Georgetown HospitalResidency, Internal Medicine, 2009 - 2012
Certifications & Licensure
PA State Medical License 2017 - 2026
VA State Medical License 2009 - 2018
DC State Medical License 2009 - 2014
American Board of Internal Medicine Gastroenterology- American Board of Internal Medicine Transplant Hepatology
Awards, Honors, & Recognition
- Outstanding Collaborative Research Team Award, ONE Group, Penn State College of Medicine 2021
- Alpha Omega Alpha (AOA) 2020
- NIH Loan Repayment Program 2018-2020
Clinical Trials
- Treatment of Type I Hepatorenal Syndrome (HRS) With Pentoxyfylline
- NASH-FITTER: Nonalcoholic Steatohepatitis Fitness Intervention Treatment Targeting Endothelial Dysfunction Reversal Start of enrollment: 2019 Nov 01
- EXALT: EXercise Attenuates Liver Tumors Trial Start of enrollment: 2019 Jan 03
Publications & Presentations
PubMed
- Higher Cardiorespiratory Fitness Is Associated With a Lower Burden of Metabolic Syndrome Traits: A Cross-Sectional Analysis of 39 197 UK Adults.Scott A Willis, Annalena Phillipp, Kevin Deighton, Christopher Goodwin, Daniel J Cuthbertson
Diabetes, Obesity & Metabolism. 2026-12-01 - Functional and Metabolic Correlates of Age- and Sex-Normalized Handgrip Strength in Children with Metabolic Dysfunction-Associated Steatotic Liver Disease.Mohit Kehar, Carolina Jimenez-Rivera, Leah Feret, Shelley E Keating, Patricia E Longmuir
Journal of Clinical Medicine. 2026-09-27 - 1 citationsMedications for Weight Loss and MASLD: A National Survey of Hepatology and Gastroenterology Provider Practices, Attitudes, and Knowledge Before Resmetirom.Gene Y Im, Amon Asgharpour, Elizabeth S Aby, Jonathan G Stine, Jessica L Mellinger
Journal of Clinical Gastroenterology. 2026-09-01
Press Mentions
The Link Between Your Heart Health and MASHJanuary 31st, 2025- Exercise Can Help Shed Dangerous Fat Around the LiverFebruary 13th, 2023
- Exercise May Lower Clotting Risk in Patients with NASHMarch 8th, 2022
Grant Support
- Establishing the mechanism of benefit and dose of exercise required to improve liver histology in patients with nonalcoholic steatohepatitisPENNSYLVANIA STATE UNIV HERSHEY MED CTR2022–2026
External Links
- Stine Laboratoryhttps://research.med.psu.edu/liver/
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