ThomasMaMD

PubMed

• Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inf...
  Kushal Saha, Ashwinkumar Subramenium Ganapathy, Alexandra Wang, Priya Arumugam, Nathan Michael Morris, Leonard Harris, Gregory Yochum, Walter Koltun, Gary H Perdew, Me...> ;Mucosal Immunology. 2023 Dec 1
• 3 citations
  Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways.
  Ashwinkumar Subramenium Ganapathy, Kushal Saha, Alexandra Wang, Priya Arumugam, Viszwapriya Dharmaprakash, Gregory Yochum, Walter Koltun, Meghali Nighot, Gary Perdew, ...> ;Cell Reports. 2023 Jul 25
• Editorial: Role of matrix metalloproteinases and other inflammatory mediators in the disruption of the intestinal tight junction barrier.
  Rana Al-Sadi, Raz Abdulqadir, Thomas Y Ma> ;Frontiers in Immunology. 2023 Jan 1
• 3 citations
  Long-Term Use of Proton Pump Inhibitors Disrupts Intestinal Tight Junction Barrier and Exaggerates Experimental Colitis.
  Meghali Nighot, Pei-Luan Liao, Nathan Morris, Dennis McCarthy, Viszwapriya Dharmaprakash, Inam Ullah Khan, Shannon Dalessio, Kushal Saha, Ashwinkumar Subramaniam Ganap...> ;Journal of Crohn's & Colitis. 2023 Apr 19
• 12 citations
  Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macro...
  Kushal Saha, Ashwinkumar Subramenium Ganapathy, Alexandra Wang, Nathan Michael Morris, Eric Suchanec, Wei Ding, Gregory Yochum, Walter Koltun, Meghali Nighot, Thomas M...> ;Journal of Crohn's & Colitis. 2023 Apr 3
• 23 citations
  AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability.
  Ashwinkumar Subramenium Ganapathy, Kushal Saha, Eric Suchanec, Vikash Singh, Aayush Verma, Gregory Yochum, Walter Koltun, Meghali Nighot, Thomas Ma, Prashant Nighot> ;Autophagy. 2022 Sep 1
• 31 citations
  Matrix Metalloproteinase MMP-12 Promotes Macrophage Transmigration Across Intestinal Epithelial Tight Junctions and Increases Severity of Experimental Colitis.
  Meghali Nighot, Ashwinkumar Subramenium Ganapathy, Kushal Saha, Eric Suchanec, Eliseo F. Castillo, Alyssa D. Gregory, Steven D. Shapiro, Thomas Y. Ma, Prashant Nighot> ;Journal of Crohn's & Colitis. 2021 Oct 7
• 38 citations
  Bifidobacterium bifidum Enhances the Intestinal Epithelial Tight Junction Barrier and Protects against Intestinal Inflammation by Targeting the Toll-like Receptor-2 Pa...
  Rana Al-Sadi, Viszwapriya Dharmaprakash, Prashant Nighot, Shuhong Guo, Meghali Nighot, Toan Do, Thomas Y. Ma> ;International Journal of Molecular Sciences. 2021 Jul 28
• 27 citations
  Matrix Metalloproteinase-9 (MMP-9) induced disruption of intestinal epithelial tight junction barrier is mediated by NF-κB activation.
  Rana Al-Sadi, Jessica Engers, Mohammad Rashedul Haque, Steven H. King, Deemah Al-Omari, Thomas Y. Ma> ;Plos One. 2021 Apr 7
• 41 citations
  Lactobacillus acidophilus Induces a Strain-specific and Toll-Like Receptor 2-Dependent Enhancement of Intestinal Epithelial Tight Junction Barrier and Protection Again...
  Rana Al-Sadi, Prashant Nighot, Meghali Nighot, Mohammad Rashedul Haque, Manmeet Rawat, Thomas Y. Ma> ;The American Journal of Pathology. 2021 Feb 16
• 16 citations
  Endocytosis of Intestinal Tight Junction Proteins: In Time and Space
  Prashant Nighot, Thomas Y. Ma> ;Inflammatory Bowel Diseases. 2021 Jan 19
• 114 citations
  IL-1β and the Intestinal Epithelial Tight Junction Barrier
  Lauren W. Kaminsky, Rana Al-Sadi, Thomas Y. Ma> ;Frontiers in Immunology. 2021 Jan 1
• 8 citations
  The Gut Microbiome and Alcoholic Liver Disease: Ethanol Consumption Drives Consistent and Reproducible Alteration in Gut Microbiota in Mice.
  Erick S. LeBrun, Meghali Nighot, Viszwapriya dharmaprakash, Anand Kumar, Chien Chi Lo, Patrick S. G. Chain, Thomas Y. Ma> ;Life. 2020 Dec 24
• 86 citations
  IL1B Increases Intestinal Tight Junction Permeability by Up-regulation of MIR200C-3p, Which Degrades Occludin mRNA
  Manmeet Rawat, Meghali Nighot, Rana Al-Sadi, Yash Gupta, Dharmaprakash Viszwapriya, Gregory S. Yochum, Walter A. Koltun, Thomas Y. Ma> ;Gastroenterology. 2020 Oct 1
• 32 citations
  Intestinal epithelial tight junction barrier regulation by autophagy-related protein ATG6/beclin 1.
  Morgan Wong, Ashwinkumar Subramenium Ganapathy, Eric Suchanec, Laura L. Laidler, Thomas Y. Ma, Prashant Nighot> ;American Journal of Physiology. Cell Physiology. 2019 May 1
• 47 citations
  Lipopolysaccharide-Induced Increase in Intestinal Permeability Is Mediated by TAK-1 Activation of IKK and MLCK/MYLK Gene.
  Meghali Nighot, Manmeet Rawat, Rana Al-Sadi, Eliseo F. Castillo, Prashant Nighot, Thomas Y. Ma> ;The American Journal of Pathology. 2019 Apr 1
• 36 citations
  MMP-9-induced increase in intestinal epithelial tight permeability is mediated by p38 kinase signaling pathway activation of MLCK gene.
  Rana Al-Sadi, Moustafa A. Youssef, Manmeet Rawat, Shuhong Guo, Karol Dokladny, Mohammad Rashedul Haque, Martin Watterson, Thomas Y. Ma> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2019 Feb 1
• Using multiple x-ray emission images of inertially confined implosions to identify spatial variations and estimate confinement volumes (invited).
  Benedetti, L. R.,Bradley, D. K.,Khan, S. F.,Izumi, N.,Ma, T.,Nagel, S. R.,Pak, A.> ;Rev Sci Instrum. 2018 Nov 08
• Absolute Equation-of-State Measurement for Polystyrene from 25 to 60 Mbar Using a Spherically Converging Shock Wave.
  Döppner, T.,Swift, D. C.,Kritcher, A. L.,Bachmann, B.,Collins, G. W.,Chapman, D. A.,Hawreliak, J.,Kraus, D.,Nilsen, J.,Rothman, S.,Benedict, L. X.,Dewald, E.,Fratanduo...> ;Phys. Rev. Lett.. 2018 Aug 08
• 46 citations
  Expression of Programmed Death-Ligand 1 by Human Colonic CD90+ Stromal Cells Differs Between Ulcerative Colitis and Crohn's Disease and Determines Their Capacity to Su...
  Ellen J. Beswick, Carl Grim, Abinav Singh, Jose E. Aguirre, Marissa A. Tafoya, Suimin Qiu, Gerhard Rogler, Rohini McKee, Von G. Samedi, Thomas Y. Ma, Victor E. Reyes, ...> ;Frontiers in Immunology. 2018 May 30
• 124 citations
  Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88)...
  Meghali Nighot, Rana Al-Sadi, Shuhong Guo, Manmeet Rawat, Prashant K. Nighot, Martin Watterson, Thomas Y. Ma> ;The American Journal of Pathology. 2017 Dec 1
• 25 citations
  Chloride channel ClC- 2 enhances intestinal epithelial tight junction barrier function via regulation of caveolin-1 and caveolar trafficking of occludin.
  Prashant K. Nighot, Lana Leung, Thomas Y. Ma> ;Experimental Cell Research. 2017 Mar 1
• 57 citations
  Intestinal barrier dysfunction in human necrotizing enterocolitis
  Sarah A. Moore, Prashant K. Nighot, Cynthia Reyes, Manmeet Rawat, Jason McKee, David G Lemon, Joshua A. Hanson, Thomas Y. Ma> ;Journal of Pediatric Surgery. 2016 Dec 1
• 30 citations
  Role of autophagy in the regulation of epithelial cell junctions
  Prashant K. Nighot, Thomas Y. Ma> ;Tissue Barriers. 2016 Jun 9
• 127 citations
  TNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway
  Rana Al-Sadi, Shuhong Guo, Dongmei Ye, Manmeet Rawat, Thomas Y. Ma> ;The American Journal of Pathology. 2016 May 1
• Join now to see all