JorgeJuanVelardeMDPhD

PubMed

• 5 citations
  Interplay between human STING genotype and bacterial NADase activity regulates inter-individual disease variability.
  Elin Movert, Jaume Salgado Bolarin, Christine Valfridsson, Jorge Velarde, Steinar Skrede, Michael Nekludov, Ole Hyldegaard, Per Arnell, Mattias Svensson, Anna Norrby-T...> ;Nature Communications. 2023 Jul 6
• 1 citations
  Streptococcus pyogenes can support or inhibit growth of Haemophilus influenzae by supplying or restricting extracellular NAD.
  Hyunju Lee, Rebecca J Edgar, Ian J Lichtenstein, Jorge J Velarde, Natalia Korotkova, Michael R Wessels> ;Plos One. 2022 Jan 1
• 5 citations
  Structure of the Streptococcus pyogenes NADase translocation domain and its essential role in toxin binding to oropharyngeal keratinocytes.
  Jorge J. Velarde, Alessandro Piai, Ian J Lichtenstein, Nicola N Lynskey, James J. Chou, Michael R. Wessels> ;Journal of Bacteriology. 2021 Oct 25
• 15 citations
  RocA Binds CsrS To Modulate CsrRS-Mediated Gene Regulation in Group A Streptococcus.
  Nicola N. Lynskey, Jorge J. Velarde, Meredith B. Finn, Simon L. Dove, Michael R. Wessels> ;Mbio. 2019 Jul 16
• 41 citations
  Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface.
  Xavier Carette, John Platig, David C. Young, Michaela Helmel, Albert T. Young, Zhe Wang, Lakshmi-Prasad Potluri, Cameron Stuver Moody, Jumei Zeng, Sladjana Prisic, Jos...> ;Mbio. 2018 May 2
• 20 citations
  Binding of NAD + -Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A Streptococcus .
  Jorge J. Velarde, Maghnus O'Seaghdha, Buket Baddal, Benedicte Bastiat-Sempe, Michael R. Wessels> ;Mbio. 2017 Sep 12
• 28 citations
  NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus.
  Onkar Sharma, Maghnus O'Seaghdha, Jorge J. Velarde, Michael R. Wessels> ;Plos Pathogens. 2016 Mar 3
• 45 citations
  The Human Antimicrobial Peptide LL-37 Binds Directly to CsrS, a Sensor Histidine Kinase of Group A Streptococcus, to Activate Expression of Virulence Factors
  Jorge J. Velarde, Melissa Ashbaugh, Michael R. Wessels> ;The Journal of Biological Chemistry. 2014 Dec 26
• 35 citations
  Solution structure of the novel dispersin protein of enteroaggregative Escherichia coli.
  Jorge J. Velarde, Kristen M. Varney, Keith G. Inman, Mauricio J. Farfan, Edward G. Dudley, Jonathan N. Fletcher, David J. Weber, James P. Nataro> ;Molecular Microbiology. 2007 Dec 1
• 38 citations
  Hydrophobic residues of the autotransporter EspP linker domain are important for outer membrane translocation of its passenger.
  Jorge J. Velarde, James P. Nataro> ;The Journal of Biological Chemistry. 2004 Jul 23
• 42 citations
  BUTYROPHILIN IS EXPRESSED IN MAMMARY EPITHELIAL CELLS FROM A SINGLE-SIZED MESSENGER RNA AS A TYPE I MEMBRANE GLYCOPROTEIN
  Lisa R. Banghart, Clayton W. Chamberlain, Jorge Velarde, Igor V. Korobko, Sherry L. Ogg, Lucinda J.W. Jack, Vikram N. Vakharia, Ian H. Mather> ;The Journal of Biological Chemistry. 1998 Feb 13
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