JosephBaarMD

Oncology • Westlake, OH

Associate Professor, Medicine, Case Western Reserve University School of Medicine

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Office
29325 Health Campus Dr
Westlake, OH 44145
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Education & Training

Newton-Wellesley HospitalResidency, Internal Medicine, 1986 - 1987
University of Western OntarioClass of 1984

Certifications & Licensure

OH State Medical License 2006 - 2023
PA State Medical License 1994 - 2014
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Fellow (FACP) American College of Physicians, 2003

Clinical Trials

S0500 Treatment Decision Making Based on Blood Levels of Tumor Cells for Metastatic Breast Cancer Treated With Chemo Start of enrollment: 2006 Oct 01
Completed
Phase 3
Epothilone B in Treating Patients With CNS Metastases From Breast Cancer Start of enrollment: 2007 Jan 01
Completed
Phase 2
Fatigue Caused by Chemotherapy in Women Who Have Undergone Surgery for Breast Cancer and in Healthy Volunteers Start of enrollment: 2008 Jul 01
Terminated
Docetaxel,Carboplatin,Trastuzumab and Bevacizumab for Breast Cancer and Bone Marrow Micrometastases Start of enrollment: 2009 Dec 01
Completed
Early Phase 1
MUC1 Vaccine for Triple-negative Breast Cancer Start of enrollment: 2009 Aug 19
Completed
Early Phase 1
A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer Start of enrollment: 2010 Aug 13
Completed
Phase 3
Type I-Polarized Autologous Dendritic Cell Vaccine With Tumor Blood Vessel Antigen-Derived Peptides in Metastatic Breast Cancer Patients Start of enrollment: 2015 Jul 17
Completed
Phase 1
Carboplatin, Nab-Paclitaxel and Pembrolizumab for Metastatic Triple-Negative Breast Cancer Start of enrollment: 2017 May 19
Completed
Phase 2
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Publications & Presentations

PubMed

Phase II Clinical Trial of Pembrolizumab and Chemotherapy Reveals Distinct Transcriptomic Profiles by Radiologic Response in Metastatic Triple-Negative Breast Cancer.
Avia D Wilkerson, Prerana Bangalore Parthasarathy, Nickolas Stabellini, Carley Mitchell, Paul G Pavicic Jr, Pingfu Fu, Amit Rupani, Hana Husic, Patricia A Rayman, Shad...> ;Clinical Cancer Research. 2024 Jan 5
23 citations
Randomized phase II trial of fulvestrant alone or in combination with bortezomib in hormone receptor-positive metastatic breast cancer resistant to aromatase inhibitor...
Kerin B. Adelson, Bhuvaneswari Ramaswamy, Joseph A. Sparano, Paul J. Christos, John J. Wright, George Raptis, Gang Han, Miguel A. Villalona-Calero, Cynthia X. Ma, Dawn...> ;NPJ Breast Cancer. 2016 Dec 14
20 citations
Phase II trial of patupilone in patients with brain metastases from breast cancer
David M. Peereboom, Conleth G. Murphy, Manmeet Ahluwalia, Alison Conlin, April F. Eichler, Catherine Van Poznak, Joseph Baar, Paul Elson, Andrew D. Seidman> ;Neuro-Oncology. 2014 Apr 1
60 citations
MUC1 is expressed at high frequency in early-stage basal-like triple-negative breast cancer.
Alan E. Siroy, Fadi W. Abdul-Karim, John D. Miedler, Nancy Fong, Pingfu Fu, Hannah Gilmore, Joseph Baar> ;Human Pathology. 2013 Oct 1
80 citations
A Vasculature-Targeting Regimen of Preoperative Docetaxel with or without Bevacizumab for Locally Advanced Breast Cancer: Impact on Angiogenic Biomarkers
Joseph Baar, Paula Silverman, Janice A. Lyons, Pingfu Fu, Fadi W. Abdul-Karim, Nicholas P. Ziats, Jay Wasman, Paul Hartman, John A. Jesberger, L. Dumadag, Erin Hohler,...> ;Clinical Cancer Research. 2009 May 15
3 citations
Optimized systemic dosing with CpG DNA enhances dendritic cell-mediated rejection of a poorly immunogenic mammary tumor in BALB/c mice.
Quan Cai, Lyubov Kublo, Rachel Cumberland, William E. Gooding, Joseph Baar> ;Clinical and Translational Science. 2009 Feb 1
2 citations
Biological therapy of breast cancer: recent clinical applications.
Joseph Baar> ;Current Opinion in Investigational Drugs. 2007 Dec 1
34 citations
Phase I trial of BAY 50-4798, an interleukin-2-specific agonist in advanced melanoma and renal cancer
Kim Margolin, Michael B. Atkins, Janice P. Dutcher, Marc S. Ernstoff, Joseph I. Clark, Joseph Baar, Jeffrey A. Sosman, Jeffrey S. Weber, Chetan Lathia, Janice Brunetti...> ;Clinical Cancer Research. 2007 Jun 1
91 citations
Long‐term survivors after gamma knife radiosurgery for brain metastases
Douglas Kondziolka, Juan J. Martin, John C. Flickinger, David M. Friedland, Adam Brufsky, Joseph Baar, Sanjiv Agarwala, John M. Kirkwood, L. Dade Lunsford> ;Cancer. 2005 Dec 15
1 citations
Evaluation of the OncoTCap (Oncology Thinking Cap) simulation in teaching medical students about clinical trials: some successes and some surprises.
Roger Day, Brenda K. Manning, Denise Garrott, Adam M. Brufsky, Joseph Baar, Merrill J. Egorin, William E. Shirey, Charles Friedman> ;Journal of Cancer Education. 2004 Jan 1
75 citations
Enzyme-linked Immunospot, Cytokine Flow Cytometry, and Tetramers in the Detection of T-Cell Responses to a Dendritic Cell-based Multipeptide Vaccine in Patients with M...
Theresa L. Whiteside, Yongxiang Zhao, Takashi Tsukishiro, Elaine M. Elder, William E. Gooding, Joseph Baar> ;Clinical Cancer Research. 2003 Feb 1
23 citations
Murine dendritic cell-induced tumor apoptosis is partially mediated by nitric oxide.
Hiromune Shimamura, Rachel Cumberland, Kazumasa Hiroishi, Simon C. Watkins, Michael T. Lotze, Joseph Baar> ;Journal of Immunotherapy. 2002 May 1
2 citations
Oncology Thinking Cap: Scaffolded Use of a Simulation to Learn Clinical Trial Design
Cindy E. Hmelo, Sailesh Ramakrishnan, Roger Day, William Shirey, Adam Brufsky, Candace S. Johnson, Joseph Baar, Qingshou Huang> ;Teaching and Learning in Medicine. 2001 Jan 1
14 citations
Clinical applications of dendritic cell cancer vaccines.
Joseph Baar> ;The Oncologist. 1999 Apr 1
10 citations
DNA Vaccines Targeting Dendritic Cells for the Immunotherapy of Cancer
Thomas Tüting, Cara C. Wilson, Dina M. Martin, Joseph Baar, Albert B. DeLeo, Michael T. Lotze, Walter J. Storkus> ;Advances in Experimental Medicine and Biology. 1998 Jan 1
8 citations
Potentiation of E7 antisense RNA-induced antitumor immunity by co-delivery of IL-12 gene in HPV16 DNA-positive mouse tumor
Yukai He, Vivian Wai Yan Lui, Joseph Baar, L. Wang, Michael R. Shurin, Ciprian Almonte, Simon C. Watkins, Leaf Huang> ;Gene Therapy. 1998 Jan 1
154 citations
Autologous Human Monocyte-Derived Dendritic Cells Genetically Modified to Express Melanoma Antigens Elicit Primary Cytotoxic T Cell Responses In Vitro: Enhancement by ...
Thomas Tüting, Cara C. Wilson, Dina M. Martin, Yvette L. Kasamon, Jennifer L. Rowles, Debora I. Ma, Craig L. Slingluff, Stephan Wagner, Pierre van der Bruggen, Joseph ...> ;Journal of Immunology. 1998 Feb 1
36 citations
Interferon-α gene therapy for cancer: retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene d...
Thomas Tüting, Andrea Gambotto, Joseph Baar, Ian D. Davis, Walter J. Storkus, Paul J. Zavodny, Satwant K. Narula, Hideaki Tahara, Paul D. Robbins, Michael T. Lotze> ;Gene Therapy. 1997 Oct 1
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Press Mentions

UH Seidman Cancer Center Expert Presents Triple-Negative Breast Cancer Immunotherapy TrialDecember 8th, 2016

Professional Memberships

American Society of Clinical Oncology - ASCO
Member
American College of Physicians - ACP
Fellow

Hospital Affiliations

University Hospitals Cleveland Medical CenterCleveland, Ohio
West Medical CenterWilloughby, Ohio