Joshua H Lipschutz MD

Hereditary Kidney Disease Genetics

Renal Division Director, Professor of Medicine and Arthur V. Williams Chair, Medical University of South Carolina

Education & Training

Indiana University School of MedicineResidency, Internal Medicine, 1989 - 1991
Michael Reese Hospital and Medical CenterInternship, Internal Medicine, 1988 - 1989
Indiana University School of MedicineClass of 1988
Indiana UniversityB.A., Chemistry, 1980 - 1984
University of California (San Francisco)Fellowship, Nephrology

CMS Meaningful Use Stage 1 Certification Beacon Oncology 2014 Certified Module, Epic Systems Corporation, 2016
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2016
NIH KO8 Mentored Scientist Career Development Award (to Dr. Ben Fogelgren in the Lipschutz Lab) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), 2011

PubMed

Deletion of exocyst component 5 suppresses repair of injured kidney by limiting cell proliferation.
Hui Jae Lim, Min Jung Kong, Mira Noh, You Ri Park, Yong Kwon Han
Cell Death Discovery. 2026-04-24
Beta 2 adrenergic receptor agonists as a treatment for metabolic dysfunction-associated steatohepatitis (MASH).
Brennan S Winkler, Kristina M Stayer, Abhinav K Rao, Ehtesham Arif, Tsultrim T Mendenhall
Npj Metabolic Health and Disease. 2026-03-25
Deficiency of exocyst complex component Exoc5 exacerbates the progression of kidney fibrosis.
Hui Jae Lim, Yong Kwon Han, Mi Ra Noh, You Ri Park, Se Young Jang
Experimental & Molecular Medicine. 2026-03-01

Journal Articles

Novel MAPK-dependent and independent tubulogenesis genes identified via microarray analysis of 3D-cultured Madin-Darby canine kidney cells
Chacon-Heszele MF, Zuo X, Hellman NE, McKenna S, Choi SY, Huang L, Tobias JW, Park KM, Lipschutz JH, American Journal of Physiology, Renal Physiology, 1/1/2014
Expression of Drosophila Forkhead Transcription Factors During Kidney Development
Baek JI, Choi SY, Chacon-Heszele MF, Zuo X, Lipschutz JH, Biochemical and Biophysical Research Communications, 1/1/2014
The Exocyst and Regulatory GTPases in Urinary Exosomes
Chacon-Heszele MF, Zuo X, Baek JI, Choi SY, Ward CJ, Lipschutz JH, Physiological Reports, 1/1/2014

Lectures

The Role of Arl13b and the Exocyst in Ciliogenesis and Exosome Signaling (Invited Talk)
Lucca, Italy - 8/4/2014
Small GTPases in Primary Ciliogenesis (Invited Speaker for Extended Talk)
Atlanta, GA - 11/7/2013
The Role of Cdc42 and the Exocyst in Polycystic Kidney Disease (Invited Lecture)
Ulsan National Institute of Science Technology, Ulsan, South Korea - 8/24/2013

Downstream Signaling: Cilia Release Ectosomes to Deliver Important Messages in the KidneyNovember 25th, 2019
Mutated Ciliary Genes Tied to Heart Valve Birth DefectSeptember 17th, 2019
Defective Cilia Linked to Heart Valve Birth DefectsSeptember 16th, 2019

The Exocyst in Ciliogenesis and Acute Kidney InjuryRALPH H JOHNSON VA MEDICAL CENTER2011–2028
The role of beta agonists in the treatment of chronic kidney diseaseRALPH H JOHNSON VA MEDICAL CENTER2022–2027
The Exocyst In Synthesis, Cystogenesis And TubulogenesisNational Institute Of Diabetes And Digestive And Kidney Diseases2005–2009
Gene Expression Changes In Early 3D Renal TubulogenesisNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2007
The Exocyst, Adpckd, And Renal OrganogenesisNational Institute Of Diabetes And Digestive And Kidney Diseases2001