JulioCRojas-MartinezMDPhD(He/Him)

Neurology • San Francisco, CA

Neurodegenerative, Dementia & Geriatrics

Assistant Professor of Neurology

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Office
675 Nelson Rising Lane, Suite 190
San Francisco, CA 94158
Phone+1 415-502-7341

Fax+1 415-476-2921
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Education & Training

University of California (San Francisco)Fellowship, Behavioral Neurology, 2014 - 2016
University of Texas Southwestern Medical CenterResidency, Neurology, 2010 - 2014
University of Texas at AustinPhD, Neuroscience, 2004 - 2009
Escuela de Medicina Ignacio A. SantosClass of 2003

Certifications & Licensure

CA State Medical License 2014 - 2025
American Board of Psychiatry and Neurology Neurology

Clinical Trials

Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss Start of enrollment: 2014 Feb 28
Completed
Phase 3
Impact of Photobiomodulation (PBM) on Biomarkers of Alzheimer's Disease Start of enrollment: 2018 Aug 16
Completed
Not Applicable
A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease Start of enrollment: 2018 Apr 30
Completed
Phase 2

Publications & Presentations

PubMed

8 citations
Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis.
Ahmed Abdelhak, Christian Cordano, W John Boscardin, Eduardo Caverzasi, Jens Kuhle, Brandon Chan, Jeffrey M Gelfand, Hao H Yiu, Frederike C Oertel, Alexandra Beaudry-R...> ;Journal of Neurology, Neurosurgery, and Psychiatry. 2022 Jun 16
56 citations
Association of Blood and Cerebrospinal Fluid Tau Level and Other Biomarkers With Survival Time in Sporadic Creutzfeldt-Jakob Disease.
Adam M. Staffaroni, Abigail O Kramer, Megan Casey, Huicong Kang, Julio C. Rojas, Christina D. Orrú, Byron Caughey, I. Elaine Allen, Joel H. Kramer, Howard J. Rosen, Ka...> ;JAMA Neurology. 2019 Aug 1
23 citations
Four-Repeat Tauopathies: Current Management and Future Treatments.
Lawren VandeVrede, Peter A. Ljubenkov, Julio C. Rojas, Ariane E. Welch, Adam L. Boxer> ;Neurotherapeutics. 2020 Oct 1
4 citations
Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.
Breton M Asken, Fanny M Elahi, Renaud La Joie, Amelia Strom, Adam M Staffaroni, Cutter A Lindbergh, Alexandra C Apple, Michelle You, Sophia Weiner-Light, Nivetha Brath...> ;Journal of Alzheimer's Disease. 2021 Jan 1
167 citations
Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic perform...
Elisabeth H. Thijssen, Renaud La Joie, Amelia Strom, Corrina Fonseca, Leonardo Iaccarino, Amy Wolf, Salvatore Spina, Isabel E. Allen, Yann Cobigo, Hilary W. Heuer, Law...> ;The Lancet. Neurology. 2021 Sep 1
13 citations
Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial.
Peter A. Ljubenkov, Lauren Edwards, Leonardo Iaccarino, Renaud La Joie, Julio C. Rojas, Mary Koestler, Baruch Harris, Bradley F. Boeve, Barbara Borroni, John C. van Sw...> ;JAMA Network Open. 2021 Sep 1
9 citations
Lower White Matter Volume and Worse Executive Functioning Reflected in Higher Levels of Plasma GFAP among Older Adults with and Without Cognitive Impairment.
Breton M Asken, Lawren VandeVrede, Julio C. Rojas, Corrina Fonseca, Adam M. Staffaroni, Fanny M. Elahi, Cutter A. Lindbergh, Alexandra C. Apple, Michelle You, Sophia W...> ;Journal of the International Neuropsychological Society. 2021 Jun 22
5 citations
Selective vulnerability to atrophy in sporadic Creutzfeldt-Jakob disease.
Kyan Younes, Julio C. Rojas, Amy Wolf, Goh M Sheng-Yang, Matteo Paoletti, Gianina Toller, Eduardo Caverzasi, Maria Luisa Mandelli, Ignacio Illán-Gala, Joel H. Kramer, ...> ;Annals of Clinical and Translational Neurology. 2021 May 5
40 citations
Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration.
Allftd and Genfi consortia> ;Neurology. 2021 Apr 7
69 citations
Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease
Ignacio Illán-Gala, Alberto Lleó, Anna Karydas, Adam M. Staffaroni, Henrik Zetterberg, Rajeev Sivasankaran, Lea T. Grinberg, Salvatore Spina, Joel H. Kramer, Eliana Ma...> ;Neurology. 2020 Nov 16
290 citations
Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET
Renaud La Joie, Adrienne Visani, Suzanne L. Baker, Jesse A. Brown, Viktoriya Bourakova, Jungho Cha, Kiran Chaudhary, Lauren Edwards, Leonardo Iaccarino, Mustafa Janabi...> ;Science Translational Medicine. 2020 Jan 1
30 citations
Open‐Label Phase 1 Futility Studies of Salsalate and Young Plasma in Progressive Supranuclear Palsy
Lawren VandeVrede, Marian L. Dale, Scott Fields, Megan Frank, Emma Hare, Hilary W. Heuer, Kellie Keith, Mary Koestler, Peter A. Ljubenkov, Dana McDermott, Noelle Ohane...> ;Movement Disorders Clinical Practice. 2020 May 1
386 citations
Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration.
Elisabeth H. Thijssen, Renaud La Joie, Amy Wolf, Amelia Strom, Ping Wang, Leonardo Iaccarino, Viktoriya Bourakova, Yann Cobigo, Hilary W. Heuer, Salvatore Spina, Lawre...> ;Nature Medicine. 2020 Mar 2
13 citations
Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia.
Andy J Liu, Adam M. Staffaroni, Julio C Rojas-Martinez, Nicholas T. Olney, Carolina Alquezar-Burillo, Peter A. Ljubenkov, Renaud La Joie, Jamie Fong, Joanne Taylor, An...> ;JAMA Neurology. 2020 Mar 1
63 citations
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.
Xu Chen, Yaqiao Li, Chao Wang, Yinyan Tang, Sue-Ann Mok, Richard M. Tsai, Julio C. Rojas, Anna Karydas, Bruce L. Miller, Adam L. Boxer, Jason E. Gestwicki, Michelle R....> ;Molecular Neurodegeneration. 2020 Jan 6
70 citations
Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndro...
Richard M. Tsai, Zachary A. Miller, Mary Koestler, Julio C. Rojas, Peter A. Ljubenkov, Howard J. Rosen, Gil D. Rabinovici, Anne M. Fagan, Yann Cobigo, Jesse A. Brown, ...> ;JAMA Neurology. 2020 Feb 1
85 citations
4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration
Eri Saijo, Michael A. Metrick, Shunsuke Koga, Piero Parchi, Irene Litvan, Salvatore Spina, Adam L. Boxer, Julio C. Rojas, Douglas Galasko, Allison Kraus, Marcello Ross...> ;Acta Neuropathologica. 2020 Jan 1
402 citations
Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis
Claire Bridel, van Wieringen Wn, Henrik Zetterberg, Betty M. Tijms, Charlotte E. Teunissen, José C. Álvarez-Cermeño, Ulf Andreasson, Markus Axelsson, David Bäckström, ...> ;JAMA Neurology. 2019 Sep 1
19 citations
Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia
Lieke H.H. Meeter, Rebecca M. E. Steketee, Dina Salkovic, Maartje E Vos, Murray Grossman, Corey T. McMillan, David J. Irwin, Adam L. Boxer, Julio C. Rojas, Nicholas T....> ;Journal of Neurology, Neurosurgery, and Psychiatry. 2019 May 23
43 citations
Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers
Lieke H.H. Meeter, Tania F. Gendron, Ana C. Sias, Lize C. Jiskoot, Silvia P. Russo, Laura Donker Kaat, Janne M. Papma, Jessica L. Panman, Emma L. van der Ende, Elise G...> ;Annals of Clinical and Translational Neurology. 2018 May 1
2 citations
Multiproteinopathy, neurodegeneration and old age: a case study.
Julio C. Rojas, Melanie L. Stephens, Gil D. Rabinovici, Joel H. Kramer, Bruce L. Miller, William W. Seeley> ;Neurocase. 2018 Jan 6
CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP.
Rojas, J. C.,Bang, J.,Lobach, I. V.,Tsai, R. M.,Rabinovici, G. D.,Miller, B. L.,Boxer, A. L.> ;Neurology. 2017 Dec 29
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Shi, Y.,Yamada, K.,Liddelow, S. A.,Smith, S. T.,Zhao, L.,Luo, W.,Tsai, R. M.,Spina, S.,Grinberg, L. T.,Rojas, J. C.,Gallardo, G.,Wang, K.,Roh, J.,Robinson, G.,Finn, M....> ;Nature. 2017 Sep 30
Genetic Prion Disease Caused by PRNP Q160X Mutation Presenting with an Orbitofrontal Syndrome, Cyclic Diarrhea, and Peripheral Neuropathy.
Fong JC, Rojas JC, Bang J, Legati A, Rankin KP, Forner S, Miller ZA, Karydas AM, Coppola G, Grouse CK, Ralph J, Miller BL, Geschwind MD> ;J. Alzheimers Dis.. 2016-11-01
Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid.
Boman A, Svensson S, Boxer A, Rojas JC, Seeley WW, Karydas A, Miller B, Kågedal K, Svenningsson P> ;J Parkinsons Dis. 2016-04-02
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