KarlaFitzgeraldLeavensMDPhD

PubMed

• Insulin Immunoassay Interference Due to Human Antimouse Antibodies in a Patient With Ketotic Hypoglycemia.
  Katherine Lord, Karla F Leavens, Diva D De Leon, Craven, M.> ;JCEM Case Reports. 2023 Mar 1
• 6 citations
  Stem cell-based multi-tissue platforms to model human autoimmune diabetes.
  Karla F Leavens, Juan R Alvarez-Dominguez, Linda T Vo, Holger A Russ, Audrey V Parent> ;Molecular Metabolism. 2022 Dec 1
• 8 citations
  Friedreich's Ataxia related Diabetes: Epidemiology and management practices.
  Jaclyn Tamaroff, Anna DeDio, Kristin Wade, McKenzie Wells, Courtney Park, Karla Leavens, Christian Rummey, Andrea Kelly, David R Lynch, Shana E McCormack> ;Diabetes Research and Clinical Practice. 2022 Apr 1
• 5 citations
  Genome Editing Human Pluripotent Stem Cells to Model β-Cell Disease and Unmask Novel Genetic Modifiers.
  Matthew N. George, Karla F. Leavens, Paul Gadue> ;Frontiers in Endocrinology. 2021 Jun 2
• 2 citations
  Hyperinsulinism in an individual with an EP300 variant of Rubinstein-Taybi syndrome.
  K. Taylor Wild, Tomoki T Nomakuchi, Sarah E Sheppard, Karla F. Leavens, Diva D. De León, Elaine H. Zackai> ;American Journal of Medical Genetics. Part A. 2021 Jan 14
• 5 citations
  Generation of a double insulin and somatostatin reporter line, SCSe001-A-3, for the advancement of stem cell-derived pancreatic islets.
  Karla F. Leavens, Chia-min Liao, Alyssa L. Gagne, Siddharth Kishore, Fabian L. Cardenas-Diaz, Deborah L. French, Paul Gadue> ;Stem Cell Research. 2021 Jan 1
• 6 citations
  A Dual Reporter EndoC-βH1 Human β-Cell Line for Efficient Quantification of Calcium Flux and Insulin Secretion
  Fabian L. Cardenas-Diaz, Karla F. Leavens, Siddharth Kishore, Catherine Osorio-Quintero, Yi-Ju Chen, Ben Z. Stanger, Pei Wang, Deborah L. French, Paul Gadue> ;Endocrinology. 2020 Feb 1
• 5 citations
  iPreP is a three-dimensional nanofibrillar cellulose hydrogel platform for long-term ex vivo preservation of human islets
  Yi-Ju Chen, Taiji Yamazoe, Karla F. Leavens, Fabian L. Cardenas-Diaz, Andrei Georgescu, Dongeun Huh, Paul Gadue, Ben Z. Stanger> ;JCI Insight. 2019 Nov 1
• 52 citations
  Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A
  Fabian L. Cardenas-Diaz, Catherine Osorio-Quintero, Maria A. Diaz-Miranda, Siddharth Kishore, Karla F. Leavens, Chintan D Jobaliya, Diana E. Stanescu, Xilma R. Ortiz-G...> ;Cell Stem Cell. 2019 Aug 1
• 60 citations
  A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition
  Min Wan, Karla F. Leavens, Roger W. Hunter, Shlomit Koren, Alexander von Wilamowitz-Moellendorff, Mingjian Lu, Santhosh Satapati, Qingwei Chu, Kei Sakamoto, Shawn C. B...> ;Cell Metabolism. 2013 Jul 2
• 262 citations
  Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1
  Mingjian Lu, Min Wan, Karla F. Leavens, Qingwei Chu, Bobby R. Monks, Sully Fernandez, Rexford S. Ahima, Kohjiro Ueki, C. Ronald Kahn, Morris J. Birnbaum> ;Nature Medicine. 2012 Mar 1
• 93 citations
  Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.
  Min Wan, Karla F. Leavens, Danish Saleh, Rachael M. Easton, David A. Guertin, Timothy R. Peterson, Klaus H. Kaestner, David M. Sabatini, Morris J. Birnbaum> ;Cell Metabolism. 2011 Oct 5
• 118 citations
  Insulin signaling to hepatic lipid metabolism in health and disease
  Karla F. Leavens, Morris J. Birnbaum> ;Critical Reviews in Biochemistry and Molecular Biology. 2011 May 20
• 217 citations
  Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin Resistance
  Karla F. Leavens, Rachael M. Easton, Gerald I. Shulman, Stephen F. Previs, Morris J. Birnbaum> ;Cell Metabolism. 2009 Nov 4
• 3 citations
  Expression of the sarco/endoplasmic Ca2+-ATPase, SERCA1a, in fibroblasts induces the formation of organelle membrane arrays
  Suzanne E. Biehn, Kirk J. Czymmek, Karla F. Leavens, Norman J. Karin> ;Experimental Cell Research. 2004 Jan 1
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