KathleenMShannonMD

Neurology • Madison, WI

Movement Disorder

Rush University Medical Group

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Office
600 Highland Ave

Madison, WI 53792
Phone+1 608-263-5442

Fax+1 608-263-0412
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Education & Training

Rush University Medical CenterFellowship, Movement Disorders, 1985 - 1987
Rush University Medical CenterResidency, Neurology, 1982 - 1987
Rush University Medical CenterInternship, Internal Medicine, 1981 - 1982
Rush Medical College of Rush University Medical CenterClass of 1981

Certifications & Licensure

IL State Medical License 1981 - 2026
WI State Medical License 2016 - 2025
TN State Medical License 1988 - 1992
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013

Clinical Trials

Creatine Safety, Tolerability, & Efficacy in Huntington's Disease (CREST-E) Start of enrollment: 2009 Sep 01
Terminated
Phase 3
Increased Gut Permeability to Lipopolysaccharides (LPS) in Parkinson's Disease Start of enrollment: 2007 Sep 01
Completed
Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort Start of enrollment: 2012 Jul 01
Recruiting

Publications & Presentations

PubMed

4 citations
Infections and Changes in Commensal Bacteria and the Pathogenesis of Parkinson's Disease.
Kathleen M Shannon> ;Journal of Parkinson's Disease. 2022 Jan 1
8 citations
Gut-Derived Sterile Inflammation and Parkinson's Disease.
Kathleen M Shannon> ;Frontiers in Neurology. 2022 Jan 1
29 citations
Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology
Madelyn C. Houser, W. Michael Caudle, Jianjun Chang, George T. Kannarkat, Yuan Yang, Sean D. Kelly, Danielle Oliver, Valerie Joers, Kathleen M. Shannon, Ali Keshavarzi...> ;Acta Neuropathologica Communications. 2021 Aug 19
6 citations
Mild Cognitive Impairment as an Early Landmark in Huntington's Disease.
Ying Zhang, Junyi Zhou, Carissa R. Gehl, Jeffrey D. Long, Hans J. Johnson, Vincent A. Magnotta, Daniel K. Sewell, Kathleen M. Shannon, Jane S. Paulsen> ;Frontiers in Neurology. 2021 Jul 7
156 citations
Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease.
Hemraj B. Dodiya, Christopher B. Forsyth, Robin M. Voigt, Phillip A. Engen, Jinal Patel, Maliha Shaikh, Stefan J. Green, Ankur Naqib, Avik Roy, Jeffrey H. Kordower, Ka...> ;Neurobiology of Disease. 2020 Feb 1
14 citations
Recent Advances in the Treatment of Huntington's Disease: Targeting DNA and RNA.
Kathleen M. Shannon> ;CNS Drugs. 2020 Mar 1
239 citations
Role of TLR4 in the gut-brain axis in Parkinson’s disease: a translational study from men to mice
Paula Perez-Pardo, Hemraj B. Dodiya, Phillip A. Engen, Christopher B. Forsyth, Andrea M Huschens, Maliha Shaikh, Robin M. Voigt, Ankur Naqib, Stefan J. Green, Jeffrey ...> ;Gut. 2019 May 1
57 citations
The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy.
Phillip A. Engen, Hemraj B. Dodiya, Ankur Naqib, Christopher B. Forsyth, Stefan J. Green, Robin M. Voigt, Jeffrey H. Kordower, Ece Mutlu, Kathleen M. Shannon, Ali Kesh...> ;Journal of Parkinson's Disease. 2017 Jan 1
85 citations
A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease
Andrew McGarry, Michael P. McDermott, Karl Kieburtz, Elisabeth A. deBlieck, Flint Beal, Karen Marder, Christopher A. Ross, Ira Shoulson, Peter R. Gilbert, William Mall...> ;Neurology. 2017 Jan 10
1967 citations
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
Timothy R. Sampson, Justine W. Debelius, Taren Thron, Stefan Janssen, Gauri G. Shastri, Zehra Esra Ilhan, Collin Challis, Catherine E. Schretter, Sandra Rocha, Viviana...> ;Cell. 2016 Dec 1
38 citations
Similar α-Synuclein staining in the colon mucosa in patients with Parkinson's disease and controls
Laurent Antunes, Sonia Frasquilho, Marek Ostaszewski, J Weber, Laura Longhino, Paul Antony, Aidos Baumuratov, Manuel Buttini, Kathleen M. Shannon, Rudi Balling, Nico J...> ;Movement Disorders. 2016 Oct 1
9 citations
Pridopidine for the treatment of Huntington’s disease
Kathleen M. Shannon> ;Expert Opinion on Investigational Drugs. 2016 Mar 10
37 citations
Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials
Kevin M. Biglan, Ira Shoulson, Karl Kieburtz, David Oakes, Elise Kayson, M. Aileen Shinaman, Hongwei Zhao, Megan Romer, Anne Young, Steven M. Hersch, J. B. Penney, Kar...> ;JAMA Neurology. 2016 Jan 1
49 citations
Therapeutic advances in Huntington's Disease
Kathleen M. Shannon, Avram Fraint> ;Movement Disorders. 2015 Sep 15
40 citations
Abnormal lipopolysaccharide binding protein as marker of gastrointestinal inflammation in Parkinson disease.
Gian Pal, Maliha Shaikh, Christopher B. Forsyth, Bichun Ouyang, Ali Keshavarzian, Kathleen M. Shannon> ;Frontiers in Neuroscience. 2015 Sep 1
731 citations
Colonic bacterial composition in Parkinson's disease.
Ali Keshavarzian, Stefan J. Green, Phillip A. Engen, Robin M. Voigt, Ankur Naqib, Christopher B. Forsyth, Ece Mutlu, Kathleen M. Shannon> ;Movement Disorders. 2015 Sep 1
163 citations
Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial
Tanya Simuni, Karl Kieburtz, Barbara C. Tilley, Jordan J. Elm, Bernard Ravina, Debra Babcock, Marina E. Emborg, Robert A. Hauser, Cornelia Kamp, John C. Morgan, G. Web...> ;The Lancet. Neurology. 2015 Aug 1
139 citations
Effect of Creatine Monohydrate on Clinical Progression in Patients With Parkinson Disease A Randomized Clinical Trial
Simon, D. K., Karl Kieburtz, Barbara C. Tilley, Jordan J. Elm, Debra Babcock, Robert A. Hauser, G. Webster Ross, Alicia H. Augustine, Erika U. Augustine, Michael J. Am...> ;JAMA. 2015 Feb 10
72 citations
Gut feelings about smoking and coffee in Parkinson's disease
Pascal Derkinderen, Kathleen M. Shannon, Patrik Brundin> ;Movement Disorders. 2014 Jul 1
182 citations
Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease.
Leo P. Kelly, Paul M. Carvey, Ali Keshavarzian, Kathleen M. Shannon, Maliha Shaikh, Roy A.E. Bakay, Jeffrey H. Kordower> ;Movement Disorders. 2014 Jul 1
75 citations
Diffusion tensor imaging of Parkinson's disease, atypical parkinsonism, and essential tremor.
Janey Prodoehl, Hong Li, Peggy J. Planetta, Christopher G. Goetz, Kathleen M. Shannon, Ruth Z. Tangonan, Cynthia L. Comella, Tanya Simuni, Xiaohong Joe Zhou, Sue Leurg...> ;Movement Disorders. 2013 Nov 1
95 citations
A randomized, double-blind, placebo-controlled trial of pridopidine in Huntington's disease
Kieburtz Karl, Andrew McGarry, Michael P. McDermott, Elise Kayson, Francis O. Walker, Jody Goldstein, Christopher Hyson, Pinky Agarwal, Patricia Deppen, Jess G. Fiedor...> ;Movement Disorders. 2013 Jan 1
311 citations
Is alpha-synuclein in the colon a biomarker for premotor Parkinson's Disease? Evidence from 3 cases†‡§
Kathleen M. Shannon, Ali Keshavarzian, Hemraj B. Dodiya, Shriram Jakate, Jeffrey H. Kordower> ;Movement Disorders. 2012 May 1
312 citations
Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease
Kathleen M. Shannon, Ali Keshavarzian, Ece Mutlu, Hemraj B. Dodiya, Delia M. Daian, Jean A. Jaglin, Jeffrey H. Kordower> ;Movement Disorders. 2012 May 1
575 citations
Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease
Christopher B. Forsyth, Kathleen M. Shannon, Jeffrey H. Kordower, Robin M. Voigt, Maliha Shaikh, Jean A. Jaglin, Jacob D. Estes, Hemraj B. Dodiya, Ali Keshavarzian> ;Plos One. 2011 Dec 1
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Press Mentions

Loneliness Could Increase Chance of Parkinson's Disease, Study IndicatesOctober 3rd, 2023
Loneliness Linked to Parkinson’s Disease Development, Researchers SayOctober 11th, 2023