KavitaDhodapkarMD

Pediatric Hematology & Oncology • Atlanta, GA

Associate Professor, Pediatrics, Yale University School of Medicine

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Office
1760 Haygood Drive NE
E322
Atlanta, GA 30322
Phone+1 404-727-9191
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Education & Training

Seth G.S. Medical CollegeClass of 1991
University of TennesseeFellowship, Pediatric Hematology/Oncology

Certifications & Licensure

GA State Medical License 2018 - 2025
CT State Medical License 2008 - 2018
NY State Medical License 1998 - 2011
AR State Medical License 1995 - 1999
MN State Medical License 1993 - 1996
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Rituximab and Hyaluronidase Human in Patients With Advanced Melanoma Undergoing Nivolumab and Ipilimumab Therapy Start of enrollment: 2019 Jun 05
Active, not recruiting
Phase 2

Publications & Presentations

PubMed

Engineering Improved CAR T Cell Products with A Multi-Cytokine Particle Platform for Hematologic and Solid Tumors.
Heather K Lin, Biaggio Uricoli, Ruby Freeman, Akm Nawshad Hossian, Zhulin He, Ji Young L Anderson, Milla Neffling, Jonathan M Legier, Dejah A Blake, Deon B Doxie, Remy...> ;Advanced Healthcare Materials. 2024 Jan 21
Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity.
Alberto Moreno, Kelly Manning, Maryam I Azeem, Ajay K Nooka, Madison Ellis, Renee Julia Manalo, Jeffrey M Switchenko, Bushra Wali, Jonathan L Kaufman, Craig C Hofmeist...> ;Research Square. 2023 Sep 21
3 citations
Regulation of antigen-specific T cell infiltration and spatial architecture in multiple myeloma and premalignancy.
M Hope Robinson, Nancy Y Villa, David L Jaye, Ajay K Nooka, Alyssa Duffy, Samuel S McCachren, Julia Manalo, Jeffrey M Switchenko, Sierra Barnes, Sayalee Potdar, Maryam...> ;The Journal of Clinical Investigation. 2023 Aug 1
2 citations
Role of B cells in immune-related adverse events following checkpoint blockade.
Kavita M Dhodapkar, Alyssa Duffy, Dhodapkar, M.> ;Immunological Reviews. 2023 Sep 1
26 citations
Changes in Bone Marrow Tumor and Immune Cells Correlate with Durability of Remissions Following BCMA CAR T Therapy in Myeloma.
Kavita M Dhodapkar, Adam D Cohen, Akhilesh Kaushal, Alfred L Garfall, Renee Julia Manalo, Allison R Carr, Samuel S McCachren, Edward A Stadtmauer, Simon F Lacey, J Jos...> ;Blood Cancer Discovery. 2022 Nov 2
9 citations
Comprehensive Characterization of the Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis.
Yao, L., Jayasinghe, R., Lee, B., Bhasin, S., Pilcher, W., Doxie, D., Gonzalez-Kozlova, E., Dasari, S., Fiala, M., Pita-Juarez, Y., Strausbauch, M., Kelly, G., Thomas,...> ;Cancer Research Communications. 2022 Oct 1
28 citations
Determinants of Neutralizing Antibody Response After SARS CoV-2 Vaccination in Patients With Myeloma.
Nooka, A., Shanmugasundaram, U., Cheedarla, N., Verkerke, H., Edara, V., Valanparambil, R., Kaufman, J., Hofmeister, C., Joseph, N., Lonial, S., Azeem, M., Manalo, J.,...> ;Journal of Clinical Oncology. 2022 Sep 10
Association of race/ethnicity with innate immune tumor microenvironment of children with B-acute lymphoblastic leukemia.
Julie R Gilbert, Himalee S Sabnis, Roman Radzievski, Deon B Doxie, Deborah DeRyckere, Sharon M Castellino, Kavita Dhodapkar> ;Journal for Immunotherapy of Cancer. 2022 Jun 1
109 citations
T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma.
Alexander X Lozano, Aadel A Chaudhuri, Aishwarya Nene, Antonietta Bacchiocchi, Noah Earland, Matthew D Vesely, Abul Usmani, Brandon E Turner, Chloé B Steen, Bogdan A L...> ;Nature Medicine. 2022 Feb 1
13 citations
Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia.
, , , , , , , , , , , , , , , > ;Blood Cancer Discovery. 2021 Sep 1
16 citations
Tandem high-dose influenza vaccination is associated with more durable serologic immunity in patients with plasma cell dyscrasias.
Andrew R. Branagan, Eamon Duffy, Geliang Gan, Fangyong Li, Connor Foster, Rakesh Verma, Lin Zhang, Terri L. Parker, Stuart Seropian, Dennis L. Cooper, Debra Brandt, Je...> ;Blood Advances. 2021 Mar 9
6 citations
Co-evolution of Immune Response in Multiple Myeloma: Implications for Immune Prevention.
Samuel S. McCachren, Kavita M. Dhodapkar> ;Frontiers in Immunology. 2021 Feb 26
3 citations
Role of MBD3-SOX2 axis in residual myeloma following pomalidomide
Rakesh Verma, Andrew R. Branagan, Mina L. Xu, Richard A. Flavell, Kavita M. Dhodapkar> ;Leukemia. 2021 Feb 18
11 citations
Viral Immunity and Vaccines in Hematologic Malignancies: Implications for COVID-19.
Kavita M Dhodapkar, Rafi Ahmed, Madhav V Dhodapkar> ;Blood Cancer Discovery. 2021 Jan 1
20 citations
SITC cancer immunotherapy resource document: a compass in the land of biomarker discovery.
Siwen Hu-Lieskovan, Srabani Bhaumik, Kavita M. Dhodapkar, Jean-Charles Grivel, Sumati Gupta, Brent A. Hanks, Sylvia Janetzki, Thomas O. Kleen, Yoshinobu Koguchi, Amand...> ;Journal for Immunotherapy of Cancer. 2020 Dec 1
19 citations
Risk-associated alterations in marrow T cells in pediatric leukemia
Jithendra Kini Bailur, Samuel S. McCachren, Katherine E. Pendleton, Juan C. Vasquez, Hong Seo Lim, Alyssa Duffy, Deon B. Doxie, Akhilesh Kaushal, Connor Foster, Debora...> ;JCI Insight. 2020 Aug 20
29 citations
Subtype and grade-dependent spatial heterogeneity of T-cell infiltration in pediatric glioma.
M. Hope Robinson, Juan C. Vasquez, Akhilesh Kaushal, Tobey J. MacDonald, José E. Velázquez Vega, Matthew Schniederjan, Kavita M. Dhodapkar> ;Journal for Immunotherapy of Cancer. 2020 Aug 1
38 citations
Differential effects of PD-L1 versus PD-1 blockade on myeloid inflammation in human cancer
, , , , , , , , , , , , , , , , , , , , > ;JCI Insight. 2020 Jun 18
15 citations
Tissue-resident memory-like T cells in tumor immunity: Clinical implications.
Kavita M. Dhodapkar> ;Seminars in Immunology. 2020 Jun 1
5 citations
Editorial: HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches.
Mirko Paiardini, Kavita M. Dhodapkar, Justin L. Harper, Steven G. Deeks, Rafi Ahmed> ;Frontiers in Immunology. 2020 Mar 31
5 citations
Moving Immunoprevention Beyond Virally Mediated Malignancies: Do We Need to Link It to Early Detection?
Kavita M. Dhodapkar> ;Frontiers in Immunology. 2019 Oct 10
8 citations
Autoimmune complications of cancer immunotherapy.
Kavita M. Dhodapkar> ;Current Opinion in Immunology. 2019 Dec 1
99 citations
Early alterations in stem-like/resident T cells, innate and myeloid cells in the bone marrow in preneoplastic gammopathy.
Jithendra Kini Bailur, Samuel S. McCachren, Deon B. Doxie, Mahesh Shrestha, Katherine E. Pendleton, Ajay K. Nooka, Natalia Neparidze, Terri L. Parker, Noffar Bar, Jona...> ;JCI Insight. 2019 Jun 6
39 citations
Checkpoint Inhibition in Myeloma: Opportunities and Challenges
Federica Costa, Rituparna Das, Jithendra Kini Bailur, Kavita M. Dhodapkar, Madhav V. Dhodapkar> ;Frontiers in Immunology. 2018 Sep 26
36 citations
Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma.
Garfall, A., Stadtmauer, E., Hwang, W., Lacey, S., Melenhorst, J., Krevvata, M., Carroll, M., Matsui, W., Wang, Q., Dhodapkar, M., Dhodapkar, K., Das, R., Vogl, D., We...> ;JCI Insight. 2018 Apr 19
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Press Mentions

Specific Components of the Tumor Immune Microenvironment May Affect the Durability of Responses to BCMA CAR T-cell TherapyAugust 29th, 2022
Immune Cell Changes Detected in Waldenstrom Macroglobulinemia (WM)September 2nd, 2021

Grant Support

Fcgamma Mediated Regulation Of Dendritic Cell FunctionNational Institute Of Allergy And Infectious Diseases2009–2011
Immune Resistance To Glioma VIA Dendritic CellsNational Institute Of Allergy And Infectious Diseases2008
Immune Resistance To Glioma VIA Dendritic CellsNational Institute Of Allergy And Infectious Diseases2004–2007
Antitumor Immune Response In Patients With Primary Brain TumorsNational Center For Research Resources2005
Antitumor Immue Response In Patients With Primary Brain TumorsNational Center For Research Resources2004