Kimberly Stegmaier MD

PubMed

• Rewiring the Fusion Oncoprotein EWSR1::FLI1 in Ewing Sarcoma with Bivalent Small Molecules.
  Michael J Bond, Ryan P Golden, Giulia DiGiovanni, Briana Howard, Roman C Sarott
  Journal of the American Chemical Society. 2025-11-27
• p300/CBP is an essential driver of pathogenic enhancer activity and gene expression in Ewing sarcoma.
  Laura C Godfrey, Brandon Regalado, Sydney R Schweber, Charles Hatton, Daniela V Wenge
  EMBO Reports. 2025-10-01
• CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias.
  Travis Fleming, Mateusz Antoszewski, Sander Lambo, Michael Gundry, Riccardo Piussi
  Blood. 2025-09-24

Journal Articles

• Creatine Kinase Pathway Inhibition Alters GSK3 and WNT Signaling in EVI1-Positive AML  
  Kimberly Stegmaier, MD, Nature
• Selective Gene Dependencies in MYCN-Amplified Neuroblastoma Include the Core Transcriptional Regulatory Circuitry  
  William C Hahn, Todd R Golub, A Thomas Look, Adam D Durbin, Neekesh V Dharia, Kimberly Stegmaier, Nature
• Genome-Scale CRISPR-Cas9 Screen Identifies Druggable Dependencies in TP53 Wild-Type Ewing Sarcoma  
  Loren D. Walensky, Kimberly Stegmaier, The Journal of Experimental Medicine
• Targeted Therapy for Fusion-Driven High-Risk Acute Leukemia  
  Kimberly Stegmaier, Yana Pikman, Blood
• Author Correction: EWS–FLI1 Increases Transcription to Cause R-loops and Block BRCA1 Repair in Ewing Sarcoma  
  Kimberly Stegmaier, Stephen L Lessnick, Jeffrey A Toretsky, Nature
• Integrated Genetic and Pharmacologic Interrogation of Rare Cancers  
  Andrew L Hong, Katherine A Janeway, Brian D Crompton, Kimberly Stegmaier, Levi A Garraway, Alanna J Church, Stuart L Schreiber, William C Hahn, Nature
• Join now to see all

Abstracts/Posters

• Targeting the Activating Mutations of NOTCH1 in T-Cell Lymphoblastic Leukemia with a New SERCA Inhibitor CAD204520
  Kimberly Stegmaier, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Targeting Salt-Inducible Kinase 3 As a Therapeutic Approach for Acute Myeloid Leukemia
  Kimberly Stegmaier, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Core Transcriptional Regulatory Circuitries in AML
  Kimberly Stegmaier, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

Lectures

• Drugging the Undruggable 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-Risk Leukemias: A Report from the LEAP ConsortiumClinically Relevant Abstract 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018