LeslieElaineLehmannMD

Pediatric Hematology & Oncology • Boston, MA

Assistant Professor, Pediatrics, Children's Hospital, Harvard Medical School

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Office
450 Brookline Ave
Boston, MA 02215
Phone+1 617-632-4882

Fax+1 617-632-2095
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Education & Training

Duke University HospitalResidency, Pediatrics, 1987 - 1992
Massachusetts General HospitalResidency, Pathology-Anatomic and Clinical, 1985 - 1987
Duke University School of MedicineClass of 1985

Certifications & Licensure

MA State Medical License 1993 - 2024
NC State Medical License 1989 - 1998
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014

Clinical Trials

Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101) Start of enrollment: 2003 Nov 01
Completed
Phase 3
Fludarabine-based Conditioning for Severe Aplastic Anemia (BMT CTN 0301) Start of enrollment: 2006 Jan 01
Completed
Phase 1, Phase 2
Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501) Start of enrollment: 2006 Dec 01
Completed
Phase 3
Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita Start of enrollment: 2012 Jul 01
Active, not recruiting
Phase 2
Busulfan, Cyclophosphamide, and Melphalan or Busulfan and Fludarabine Phosphate Before Donor Hematopoietic Cell Transplant in Treating Younger Patients With Juvenile Myelomonocytic Leukemia Start of enrollment: 2013 Jun 24
Completed
Phase 2
Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904) Start of enrollment: 2022 Apr 19
Recruiting
Phase 2
Roles: Principal Investigator
Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant Start of enrollment: 2023 Apr 04
Recruiting
Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

1 citations
A nursing perspective on inpatient sleep and circadian disruptions for pediatric stem cell transplant patients.
Zhou, E., Revette, A., Waitt, J., Emmons, K., Valenzuela, A., Redline, S., Lehmann, L., Diller, L.> ;Pediatric Blood & Cancer. 2024 Mar 1
Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation.
Franziska Wachter, Yana Pikman, Jacob Bledsoe, Malika Kapadia, Susanne Baumeister, Jared Rowe, Akiko Shimamura, Andrew E Place, Susan Prockop, Jennifer Whangbo, Leslie...> ;Clinical Case Reports. 2023 Nov 1
Sleep and circadian disruptors: Unhealthy noise and light levels for hospitalized pediatric patients.
Andrea L Fidler, Julie Waitt, Leslie E Lehmann, Jo M Solet, Jeanne F Duffy, Brian D Gonzalez, Dean W Beebe, David A Fedele, Eric S Zhou> ;Journal of Hospital Medicine. 2023 Nov 1
Survivors of Pediatric Hematopoietic Stem Cell Transplantation Exhibit Progressive Diastolic Dysfunction Over Years of Follow-Up.
Kevin P Daly, Kimberlee Gauvreau, Sonia F Epstein, Michelle L Walsh, Steve Colan, Christine Duncan, Leslie Lehmann, Ming Hui Chen, Harrison, D.> ;Transplantation and Cellular Therapy. 2023 Dec 1
4 citations
Real-world experience with low-dose IL-2 for children and young adults with refractory chronic graft-versus-host disease.
Holly Wobma, Malika Kapadia, Haesook T Kim, Francesca Alvarez-Calderon, Susanne H C Baumeister, Christine Duncan, Suzanne Forrest, Lev Gorfinkel, Jennifer Huang, Lesli...> ;Blood Advances. 2023 Aug 22
Impact of cytoreduction and remission status on hematopoietic cell transplantation outcomes in pediatric myelodysplastic syndrome and related disorders.
Franziska Wachter, Kyle Hebert, Yana Pikman, Jiemin Yang, Binita Shah, Jacob Bledsoe, Akiko Shimamura, Donna S Neuberg, Jessica A Pollard, Leslie E Lehmann> ;Pediatric Blood & Cancer. 2023 Jun 27
1 citations
Real-world experience with low-dose IL-2 for children and young adults with refractory chronic graft-versus-host disease.
Holly Wobma, Malika Kapadia, Haesook T Kim, Francesca Alvarez-Calderon, Susanne H C Baumeister, Christine Duncan, Suzanne Forrest, Lev Gorfinkel, Jennifer Huang, Lesli...> ;Blood Advances. 2023 Aug 22
3 citations
Secondary Impact of the Coronavirus Disease 19 Pandemic on Patients and the Cellular Therapy Healthcare Ecosystem.
Jane Koo, Jeffrey J Auletta, David M Hartley, John Huber, Samantha Jaglowski, Malika Kapadia, Katilyn Kusnier, Leslie Lehmann, Joseph Maakaron, Kasiani C Myers, Ahna P...> ;Transplantation and Cellular Therapy. 2022 Nov 1
2 citations
Nephroblastoma Treatment and Outcomes in a Low-Income Setting.
Cyprien Shyirambere, Chandler Villaverde, Cam Nguyen, Deogratias Ruhangaza, Aline Umwizerwa, Oscar Nsanzimana, Louis Mujyuwisha, Esperance Iradukunda, Lawrence N Shulm...> ;JCO Global Oncology. 2022 Jul 1
2 citations
A Ten-Year Experience of Treating Chronic Myeloid Leukemia in Rural Rwanda: Outcomes and Insights for a Changing Landscape.
Jennifer Morgan, Rebecca J DeBoer, Jean Bosco Bigirimana, Cam Nguyen, Deogratias Ruhangaza, Alan Paciorek, Fred Mugabo, Chandler Villaverde, Nicaise Nsabimana, Pascal ...> ;JCO Global Oncology. 2022 Jul 1
Comparison of toxicity following single versus tandem autologous transplant regimens for pediatric medulloblastoma.
Ashley S Plant-Fox, Clement Ma, Hasan Al-Sayegh, Derek Shyr, Michelle A Lee, Leslie E Lehmann, Susan N Chi> ;Pediatric Transplantation. 2022 Jun 1
1 citations
Comparison of Pulmonary Toxicity after Total Body Irradiation- and Busulfan-Based Myeloablative Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in ...
Kevin X Liu, Nicolas Poux, Kee-Young Shin, Nicholas Moore, Yu-Hui Chen, Steven Margossian, Jennifer S Whangbo, Christine N Duncan, Leslie E Lehmann, Karen J Marcus> ;Transplantation and Cellular Therapy. 2022 Aug 1
5 citations
Quality Improvement in Hematopoietic Stem Cell Transplant and Cellular Therapy: Using the Model for Improvement to impact Outcomes.
Malika Kapadia, Leslie Lehmann, Jeffery Auletta, Lisa Beatty, Neel Bhatt, Robyn Blacken, Kathy Demmel, Therese Dodd, Catherine Desmond, Taylor Fitch, Laura Flesch, Dav...> ;Transplantation and Cellular Therapy. 2022 May 1
10 citations
Candidacy for Extracorporeal Life Support in Children After Hematopoietic Cell Transplantation: A Position Paper From the Pediatric Acute Lung Injury and Sepsis Invest...
Matt S Zinter, Jennifer McArthur, Christine Duncan, Roberta Adams, Erin Kreml, Heidi Dalton, Hisham Abdel-Azim, Courtney M Rowan, Kris M Mahadeo, Adrienne G Randolph, ...> ;Pediatric Critical Care Medicine. 2022 Mar 1
4 citations
Low frequency of treatable pediatric disease alleles in gnomAD: An opportunity for future genomic screening of newborns
Nina B. Gold, Steven M. Harrison, Jared H. Rowe, Jessica Gold, Elissa M. Furutani, Alessandra Biffi, Christine Duncan, Akiko Shimamura, Leslie Lehmann, Robert C. Green> ;HGG Advances. 2022 Jan 13
Prior COVID-19 infection may increase risk for developing endothelial dysfunction following hematopoietic cell transplantation.
Sydney Ariagno, Dristhi Ragoonanan, Sajad Khazal, Kris M Mahadeo, Gabriel Salinas Cisneros, Matt S Zinter, Robyn A Blacken, Gopi Mohan, Leslie E Lehmann, Asmaa Ferdjal...> ;Frontiers in Oncology. 2022 Jan 1
6 citations
Cytokine Release Syndrome and Associated Acute Toxicities in Pediatric Patients Undergoing Immune Effector Cell Therapy or Hematopoietic Cell Transplantation.
Susanne H C Baumeister, Gopi S Mohan, Alaa Elhaddad, Leslie Lehmann> ;Frontiers in Oncology. 2022 Jan 1
Characteristics, Treatment Complexity, and Outcome of Mixed-Phenotype Acute Leukemia in Children in a Low-Middle-Income Country.
Maram Salama, Sonia Ahmed, Sonya Soliman, Nahla El-Sharkawy, Sherine Salem, Amr El-Nashar, Reham Khedr, Leslie Lehmann, Iman Sidhom, Alaa El-Haddad> ;Frontiers in Oncology. 2022 Jan 1
2 citations
Playful strategies to foster the well-being of pediatric cancer patients in the Brazilian Unified Health System: a design thinking approach.
Leandro Miletto Tonetto, Valentina Marques da Rosa, Priscila G. Brust-Renck, Megan E. Denham, Pedro Marques da Rosa, Craig Zimring, Irini Albanti, Leslie Lehmann> ;BMC Health Services Research. 2021 Sep 18
6 citations
Emerging therapeutic and preventive approaches to transplant-associated thrombotic microangiopathy
Michelle Long Schoettler, Satheesh Chonat, Kirsten M. Williams, Leslie Lehmann> ;Current Opinion in Hematology. 2021 Nov 1
7 citations
Safety of Surgical Fertility Preservation Procedures in Children Prior to Hematopoietic Stem Cell Transplant.
Katelynn Brodigan, Malika Kapadia, A. Lindsay Frazier, Marc R. Laufer, Richard N. Yu, Brent R. Weil, Elizabeth S. Ginsburg, Christine Duncan, Leslie Lehmann> ;Transplantation and Cellular Therapy. 2021 Apr 13
1 citations
Author Correction: Diagnosis, grading and management of toxicities from immunotherapies in children, adolescents and young adults with cancer.
Dristhi Ragoonanan, Sajad Khazal, Hisham Abdel-Azim, David McCall, Branko Cuglievan, Francesco Paolo Tambaro, Ali Haider Ahmad, Courtney M. Rowan, Cristina Gutierrez, ...> ;Nature Reviews. Clinical Oncology. 2021 Mar 17
21 citations
Diagnosis, grading and management of toxicities from immunotherapies in children, adolescents and young adults with cancer
Dristhi Ragoonanan, Sajad Khazal, Hisham Abdel-Azim, David McCall, Branko Cuglievan, Francesco Paolo Tambaro, Ali Haider Ahmad, Courtney M. Rowan, Cristina Gutierrez, ...> ;Nature Reviews. Clinical Oncology. 2021 Feb 19
170 citations
Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease
Erica B. Esrick, Leslie Lehmann, Alessandra Biffi, Maureen Achebe, Christian Brendel, Marioara F. Ciuculescu, Heather Daley, Brenda L. MacKinnon, Emily Morris, Amy Fed...> ;The New England Journal of Medicine. 2021 Jan 21
37 citations
A pragmatic multi-institutional approach to understanding transplant-associated thrombotic microangiopathy after stem cell transplant.
Christopher E. Dandoy, Seth J. Rotz, Priscila Badia Alonso, Anna Klunk, Catherine Desmond, John Huber, Hannah Ingraham, Christine Higham, Christopher C. Dvorak, Christ...> ;Blood Advances. 2021 Jan 12
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Journal Articles

Management Guidelines for Paediatric Patients Receiving Chimeric Antigen Receptor T Cell Therapy
Kris M Mahadeo, Julie C Fitzgerald, Marie E Steiner, Partow Kebriaei, Katayoun Rezvani, Ira M Cheifetz, John M Slopis, Paul L Martin, Sattva S Neelapu, Agne Tarasevici..., Nature

Abstracts/Posters

Ten Years of Treating Chronic Myeloid Leukemia in Rural Rwanda: Feasible Approaches for Low-Resource Settings
Leslie E. Lehmann, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Report on the Treatment of Hodgkin Lymphoma with ABVD Chemotherapy at Two Rural District Hospitals in Rwanda
Leslie E. Lehmann, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

Transplant Associated Thrombotic Microangiopathy (TA-TMA): Lessons Learned from a Large Pediatric Center
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Hospital Affiliations

Dana-Farber Cancer InstituteBoston, Massachusetts
Boston Children's HospitalBoston, Massachusetts