Kiran Musunuru MD
Adult Congenital Heart Disease
Associate Professor, Medicine - Perelman School of Medicine at the University of Pennsylvania
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3400 Civic Center Blvd, Bldg 42111-104 Smilow Center for Translational ResearchPhiladelphia, PA 19104
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Education & Training
Johns Hopkins UniversityFellowship, Cardiovascular Disease, 2006 - 2009
Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 2004 - 2006
Weill Cornell MedicineClass of 2004
Certifications & Licensure
PA State Medical License 2017 - 2026
MA State Medical License 2008 - 2017
American Board of Internal Medicine Cardiovascular Disease
Publications & Presentations
PubMed
- 1 citationsAdvancing gene-editing platforms to improve the viability of rare-disease therapeutics: key insights from a 2024 Scientific Exchange hosted by ARM, ISCT, and Danaher.Fyodor Urnov, Sadik Kassim, Kiran Musunuru, David Liu, Ann Lee
Cytotherapy. 2025-10-01 - Gene therapy and genome editing for lipoprotein disorders.Chen Gurevitz, Archna Bajaj, Amit V Khera, Ron Do, Heribert Schunkert
European Heart Journal. 2025-09-15 - Moving Therapeutic Genome Editing into Global Clinical Trials and Medicine.Kiran Musunuru, Fyodor Urnov
The CRISPR Journal. 2025-08-01
Journal Articles
- In Utero CRISPR-Mediated Therapeutic Editing of Metabolic GenesWilliam H Peranteau, Philip W Zoltick, Kiran Musunuru, William Zacharias, Nature
- Author Correction: Regulatory Variants at KLF14 Influence Type 2 Diabetes Risk via a Female-Specific Effect on Adipocyte Size and Body CompositionCalvin Pan, Kiran Musunuru, Avanthi Raghavan, Nature
- Circular Non-Coding RNA ANRIL Modulates Ribosomal RNA Maturation and Atherosclerosis in HumansKiran Musunuru, MD, Nature
Press Mentions
After Custom CRISPR Success, New Center Launches with $20M to Treat More Kids with Rare Genetic DiseasesJuly 8th, 2025- In a First, CRISPR Used to Treat Infant with Ultra-Rare DiseaseMay 15th, 2025
- 'Unbelievably Blessed': First Custom CRISPR Therapy Alleviates Worst of Rare Genetic Disease for InfantMay 15th, 2025
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Grant Support
- Personalized prime editing as a platform for hepatic inborn errors of metabolismCHILDREN'S HOSP OF PHILADELPHIA2024–2028
- Personalized prime editing as a platform for hepatic inborn errors of metabolismCHILDREN'S HOSP OF PHILADELPHIA2024–2028
- Replication study of in vivo postnatal gene editing for metabolic liver disease in the nonhuman primate modelCHILDREN'S HOSP OF PHILADELPHIA2023–2028
- Postnatal and Prenatal Therapeutic Base Editing for Metabolic DiseasesCHILDREN'S HOSP OF PHILADELPHIA2023–2028
- Diagnosis, Prevention, And Treatment Of Cardiovascular Diseases With Genome EditingUNIVERSITY OF PENNSYLVANIA2019–2026
- Diagnosis, Prevention, And Treatment Of Cardiovascular Diseases With Genome EditingUNIVERSITY OF PENNSYLVANIA2019–2026
- Genetic And Functional Analyses Of A Novel Locus Associated With LDL-C And MINational Heart, Lung, And Blood Institute2010–2011
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