L. MatthewFrankMD

Child Neurology • Norfolk, VA

Professor, Pediatrics, Division of Neurology, Eastern Virginia Medical School

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Office
850 Southampton Ave
Norfolk, VA 23510
Phone+1 757-668-9920

Fax+1 757-668-9930
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Education & Training

Boston University Medical CenterResidency, Neurology, 1975 - 1978
Duke University HospitalResidency, Pediatrics, 1973 - 1975
Uconn School Of MedicineClass of 1973

Certifications & Licensure

CA State Medical License 2019 - 2025
VA State Medical License 1978 - 2024
FL State Medical License 1987 - 1998
American Board of Pediatrics Pediatrics
American Board of Psychiatry and Neurology Neurology with Special Qualification in Child Neurology

Clinical Trials

A Study of Tadalafil for Duchenne Muscular Dystrophy Start of enrollment: 2013 Sep 01
Terminated
Phase 3

Publications & Presentations

PubMed

64 citations
Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice.
Anna K. Gillespie, Daniela A. Astudillo Maya, Eric L. Denovellis, Daniel F. Liu, David B. Kastner, Michael E. Coulter, Demetris K. Roumis, Uri T. Eden, Loren M. Frank> ;Neuron. 2021 Oct 6
20 citations
Hippocampal replay of experience at real-world speeds.
Eric L. Denovellis, Anna K. Gillespie, Michael E. Coulter, Marielena Sosa, Jason E. Chung, Uri T. Eden, Loren M. Frank> ;Elife. 2021 Sep 27
5 citations
Prefrontal cortical activity predicts the occurrence of nonlocal hippocampal representations during spatial navigation.
Jai Y. Yu, Loren M. Frank> ;Plos Biology. 2021 Sep 16
7 citations
Rats use memory confidence to guide decisions
Hannah R. Joo, Hexin Liang, Jason E. Chung, Charlotte Geaghan-Breiner, Jiang Lan Fan, Benjamin Philip Nachman, Adam Kepecs, Loren M. Frank> ;Current Biology. 2021 Aug 30
7 citations
Real-Time Point Process Filter for Multidimensional Decoding Problems Using Mixture Models.
Mohammad Reza Rezaei, Kensuke Arai, Loren M. Frank, Uri T. Eden, Ali Yousefi> ;Journal of Neuroscience Methods. 2021 Jan 15
5 citations
Scalable method for micro-CT analysis enables large scale quantitative characterization of brain lesions and implants.
David B. Kastner, Viktor Kharazia, Rhino Nevers, Clay Smyth, Daniela A Astudillo-Maya, Greer M Williams, Zhounan Yang, Cristofer M Holobetz, Luca Della Santina, Dilwor...> ;Scientific Reports. 2020 Nov 30
2 citations
Memory Alone Does Not Account for the Way Rats Learn a Simple Spatial Alternation Task.
David B. Kastner, Anna K. Gillespie, Peter Dayan, Loren M. Frank> ;The Journal of Neuroscience. 2020 Aug 4
23 citations
A consensus statement: Defining terms for reactivation analysis
Lisa Genzel, George Dragoi, Loren M. Frank, Karunesh Ganguly, Liset Menendez de la Prida, Brad E. Pfeiffer, Edwin M. Robertson> ;Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 2020 May 25
17 citations
Robust and replicable measurement for prepulse inhibition of the acoustic startle response.
Eric A. Miller, David B. Kastner, Michael Grzybowski, Melinda R. Dwinell, Aron M. Geurts, Loren M. Frank> ;Molecular Psychiatry. 2021 Jun 1
57 citations
Dorsal and Ventral Hippocampal Sharp-Wave Ripples Activate Distinct Nucleus Accumbens Networks
Marielena Sosa, Hannah R. Joo, Loren M. Frank> ;Neuron. 2020 Feb 19
113 citations
Constant Sub-second Cycling between Representations of Possible Futures in the Hippocampus.
Kenneth Kay, Jason E. Chung, Marielena Sosa, Jonathan S. Schor, Mattias P. Karlsson, Margaret C. Larkin, Daniel F. Liu, Loren M. Frank> ;Cell. 2020 Feb 6
1 citations
Erratum: Litvina et al., "BRAIN Initiative: Cutting-Edge Tools and Resources for the Community".
Elizabeth Litvina, Amy Adams, Alison L. Barth, Marcel P. Bruchez, James P. Carson, Jason E. Chung, Kristin B. Dupre, Loren M. Frank, Kathleen M. Gates, Kristen M. Harr...> ;The Journal of Neuroscience. 2020 Jan 1
3 citations
HDMF: Hierarchical Data Modeling Framework for Modern Science Data Standards
Andrew Tritt, Oliver Rubel, Benjamin Dichter, Ryan Ly, Donghe Kang, Edward F. Chang, Loren M. Frank, Kristofer E. Bouchard> ;Proceedings. 2019 Dec 1
34 citations
Early Hippocampal Sharp-Wave Ripple Deficits Predict Later Learning and Memory Impairments in an Alzheimer's Disease Mouse Model.
Emily Jones, Anna K. Gillespie, Seo Yeon Yoon, Loren M. Frank, Yadong Huang> ;Cell Reports. 2019 Nov 19
26 citations
A microfabricated, 3D-sharpened silicon shuttle for insertion of flexible electrode arrays through dura mater into brain.
Hannah R. Joo, Jiang Lan Fan, Supin Chen, Jeanine A. Pebbles, Hexin Liang, Jason E. Chung, Allison M. Yorita, Angela C. Tooker, Vanessa Tolosa, Charlotte Geaghan-Brein...> ;Journal of Neural Engineering. 2019 Oct 29
14 citations
BRAIN Initiative: Cutting-Edge Tools and Resources for the Community
Elizabeth Litvina, Amy Adams, Alison L. Barth, Marcel P. Bruchez, James P. Carson, Jason E. Chung, Kristin B. Dupre, Loren M. Frank, Kathleen M. Gates, Kristen M. Harr...> ;The Journal of Neuroscience. 2019 Oct 16
12 citations
Chronic Implantation of Multiple Flexible Polymer Electrode Arrays.
Jason E. Chung, Hannah R. Joo, Clay Smyth, Jiang Lan Fan, Charlotte Geaghan-Breiner, Hexin Liang, Daniel Fan Liu, Demetris K. Roumis, Supin Chen, Kye Y Lee, Jeanine A....> ;Journal of Visualized Experiments. 2019 Oct 4
5 citations
Efficient Decoding of Multi-Dimensional Signals From Population Spiking Activity Using a Gaussian Mixture Particle Filter
Ali Yousefi, Anna K. Gillespie, Jennifer A. Guidera, Mattias P. Karlsson, Loren M. Frank, Uri T. Eden> ;IEEE Transactions on Bio-Medical Engineering. 2019 Mar 27
31 citations
Three brain states in the hippocampus and cortex.
Kenneth Kay, Loren M. Frank> ;Hippocampus. 2019 Mar 1
147 citations
High-Density, Long-Lasting, and Multi-region Electrophysiological Recordings Using Polymer Electrode Arrays.
, , , , , , , , , , , , , , , > ;Neuron. 2019 Jan 2
183 citations
The hippocampal sharp wave–ripple in memory retrieval for immediate use and consolidation
Hannah R. Joo, Loren M. Frank> ;Nature Reviews. Neuroscience. 2018 Dec 1
78 citations
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.
A. Jeremy Willsey, Montana T. Morris, Sheng Wang, Helen Rankin Willsey, Nawei Sun, Nia Teerikorpi, Tierney Baum, Gerard Cagney, Kevin J. Bender, Tejal A. Desai, Deepak...> ;Cell. 2018 Jul 26
1 citations
Are We There Yet? Identification of Reward-Selective Cells in the Hippocampus.
Marielena Sosa, Loren M. Frank> ;Neuron. 2018 Jul 11
5 citations
A Comparison Study of Point-Process Filter and Deep Learning Performance in Estimating Rat Position Using an Ensemble of Place Cells
Mohammad Reza Rezaei, Anna K. Gillespie, Jennifer A. Guidera, Behzad Nazari, Saeid Sadri, Loren M. Frank, Uri T. Eden, Ali Yousefi> ;Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2018 Jul 1
31 citations
Specific hippocampal representations are linked to generalized cortical representations in memory
Jai Y. Yu, Daniel F. Liu, Adrianna Loback, Irene Grossrubatscher, Loren M. Frank> ;Nature Communications. 2018 Jun 7
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Hospital Affiliations

Children's Hospital of The King's DaughtersNorfolk, Virginia