LaineJMurpheyMDPhD

PubMed

• 26 citations
  Urinary free cortisol: an intermediate phenotype and a potential genetic marker for a salt-resistant subset of essential hypertension.
  Bindu Chamarthi, Nikheel S. Kolatkar, Steven C. Hunt, Jonathan S. Williams, Ellen W. Seely, Nancy J. Brown, Laine J. Murphey, Xavier Jeunemaitre, Gordon H. Williams> ;The Journal of Clinical Endocrinology and Metabolism. 2007 Apr 1
• 61 citations
  Urinary Prostaglandin F2α Is Generated from the Isoprostane Pathway and Not the Cyclooxygenase in Humans
  Huiyong Yin, Ling Gao, Hsin-Hsiung Tai, Laine J. Murphey, Ned A. Porter, Jason D. Morrow> ;The Journal of Biological Chemistry. 2007 Jan 5
• 8 citations
  Bradykinin B2 Receptor Does Not Contribute to Blood Pressure Lowering during AT1 Receptor Blockade
  Jean LeFebvre, Ayumi Shintani, Tebeb Gebretsadik, Jeffery R. Petro, Laine J. Murphey, Nancy J. Brown> ;The Journal of Pharmacology and Experimental Therapeutics. 2007 Mar 1
• 114 citations
  Angiotensin II induces interleukin-6 in humans through a mineralocorticoid receptor-dependent mechanism.
  James M. Luther, James V. Gainer, Laine J. Murphey, Chang Yu, Douglas E. Vaughan, Jason D. Morrow, Nancy J. Brown> ;Hypertension. 2006 Dec 1
• 33 citations
  Bradykinin and Its Metabolite Bradykinin 1-5 Inhibit Thrombin-Induced Platelet Aggregation in Humans
  Laine J. Murphey, Hector A. Malave, Jeff Petro, Italo Biaggioni, Daniel W. Byrne, Douglas E. Vaughan, James M. Luther, Mias Pretorius, Nancy J. Brown> ;The Journal of Pharmacology and Experimental Therapeutics. 2006 Sep 1
• 67 citations
  Bradykinin B2 receptor knockout mice are protected from thrombosis by increased nitric oxide and prostacyclin.
  Zia Shariat-Madar, Fakhri Mahdi, Mark Warnock, Jonathon W. Homeister, Sujata Srikanth, Yelena Krijanovski, Laine J. Murphey, Ayad A. Jaffa, Alvin H. Schmaier> ;Blood. 2006 Jul 1
• 35 citations
  A single dose, three-arm, placebo-controlled, phase I study of the bradykinin B2 receptor antagonist Anatibant (LF16-0687Ms) in patients with severe traumatic brain in...
  Anthony Marmarou, Martine Guy, Laine Murphey, Francis Roy, Laure Layani, Jean-Philippe Combal, Claude Marquer, Study Investigators> ;Journal of Neurotrauma. 2005 Dec 27
• 17 citations
  Angiotensin-Converting Enzyme Inhibition Increases Basal Vascular Tissue Plasminogen Activator Release in Women But Not in Men
  Mias Pretorius, James M. Luther, Laine J. Murphey, Douglas E. Vaughan, Nancy J. Brown> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2005 Nov 1
• 13 citations
  A pilot study indicating that bradykinin B2 receptor antagonism attenuates protamine‐related hypotension after cardiopulmonary bypass
  Mias Pretorius, Frank G. Scholl, Julie A. McFarlane, Laine J. Murphey, Nancy J. Brown> ;Clinical Pharmacology and Therapeutics. 2005 Nov 1
• 29 citations
  The preparation and characterization of novel peptide antagonists to thrombin and factor VIIa and activation of protease-activated receptor 1.
  Marvin T. Nieman, Mark Warnock, Ahmed A. K. Hasan, Fakhri Mahdi, Benedict R. Lucchesi, Nancy J. Brown, Laine J. Murphey, Alvin H. Schmaier> ;The Journal of Pharmacology and Experimental Therapeutics. 2004 Nov 1
• 143 citations
  Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE2 synthesis in...
  Laine J. Murphey, Myles K. Williams, Stephanie C. Sanchez, Loretta M. Byrne, Ildiko Csiki, John A. Oates, David H. Johnson, Jason D. Morrow> ;Analytical Biochemistry. 2004 Nov 15
• 145 citations
  Uric acid and the state of the intrarenal renin-angiotensin system in humans
  Todd S. Perlstein, Olga Gumieniak, Paul N. Hopkins, Laine J. Murphey, Nancy J. Brown, Gordon H. Williams, Norman K. Hollenberg, Naomi D.L. Fisher> ;Kidney International. 2004 Oct 1
• 9 citations
  Angiotensin‐converting enzyme inhibition and smoking potentiate the kinin response to cardiopulmonary bypass
  Mias Pretorius, Julie A. McFarlane, Douglas E. Vaughan, Nancy J. Brown, Laine J. Murphey> ;Clinical Pharmacology and Therapeutics. 2004 Oct 1
• 78 citations
  Thyroid function and blood pressure homeostasis in euthyroid subjects
  Olga Gumieniak, Todd S. Perlstein, Paul N. Hopkins, Nancy J. Brown, Laine J. Murphey, Xavier Jeunemaitre, Norman K. Hollenberg, Gordon H. Williams> ;The Journal of Clinical Endocrinology and Metabolism. 2004 Jul 1
• 10 citations
  Loss of Sodium Modulation of Plasma Kinins in Human Hypertension
  Laine J. Murphey, Wendy K. Eccles, Gordon H. Williams, Nancy J. Brown> ;The Journal of Pharmacology and Experimental Therapeutics. 2004 Mar 1
• 22 citations
  Angiotensin-Converting Enzyme Inhibition Alters the Fibrinolytic Response to Cardiopulmonary Bypass
  Mias Pretorius, Laine J. Murphey, Julie A. McFarlane, Douglas E. Vaughan, Nancy J. Brown> ;Circulation. 2003 Dec 23
• 17 citations
  Acute angiotensin II increases plasma F2-isoprostanes in salt-replete human hypertensives.
  Laine J. Murphey, Jason D. Morrow, Pairunyar Sawathiparnich, Gordon H. Williams, Douglas E. Vaughan, Nancy J. Brown> ;Free Radical Biology & Medicine. 2003 Oct 1
• 34 citations
  Effect of combined AT1 receptor and aldosterone receptor antagonism on plasminogen activator inhibitor-1.
  Pairunyar Sawathiparnich, Laine J. Murphey, Sandeep Kumar, Douglas E. Vaughan, Nancy J. Brown> ;The Journal of Clinical Endocrinology and Metabolism. 2003 Aug 1
• 71 citations
  Formation of highly reactive A-ring and J-ring isoprostane-like compounds (A4/J4-neuroprostanes) in vivo from docosahexaenoic acid.
  Samuel S. Fam, Laine J. Murphey, Erin S. Terry, William E. Zackert, Yan Chen, Ling Gao, Saurabh Pandalai, Ginger L. Milne, L. Jackson Roberts, Ned A. Porter, Thomas J....> ;The Journal of Biological Chemistry. 2002 Sep 27
• 23 citations
  Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J2, to glutathione
  Brian E. Cox, Laine J. Murphey, William E. Zackert, Rebecca Chinery, Ramona Graves-Deal, Olivier Boutaud, John A. Oates, Robert J. Coffey, Jason D. Morrow> ;Biochimica Et Biophysica Acta. 2002 Sep 5
• 35 citations
  Ethnicity Affects Vasodilation, but Not Endothelial Tissue Plasminogen Activator Release, in Response to Bradykinin
  David A. Rosenbaum, Mias Pretorius, James V. Gainer, Daniel W. Byrne, Laine J. Murphey, Corrie A. Painter, Douglas E. Vaughan, Nancy J. Brown> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2002 Jun 1
• 93 citations
  Dipeptidyl Peptidase IV Activity in Patients With ACE-Inhibitor-Associated Angioedema
  Jean Lefebvre, Laine J. Murphey, Tina V. Hartert, Ru Jiao Shan, William H. Simmons, Nancy J. Brown> ;Hypertension. 2002 Feb 1
• 29 citations
  Interactive Effect of PAI-1 4G/5G Genotype and Salt Intake on PAI-1 Antigen
  Nancy J. Brown, Laine J. Murphey, Nadarajah Srikuma, Natapong Koschachuhanan, Gordon H. Williams, Douglas E. Vaughan> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2001 Jun 1
• 29 citations
  Quantification of BK1-5, the Stable Bradykinin Plasma Metabolite in Humans, by a Highly Accurate Liquid-Chromatographic Tandem Mass Spectrometric Assay
  Laine J. Murphey, David L. Hachey, Douglas E. Vaughan, Nancy J. Brown, Jason D. Morrow> ;Analytical Biochemistry. 2001 May 1
• 32 citations
  Angiotensin-(1-7) Does Not Affect Vasodilator or TPA Responses to Bradykinin in Human Forearm
  James V. Gainer, Laine J. Murphey, Douglas E. Vaughan, Nancy J. Brown, Terry Wilsdorf> ;Hypertension. 2001 Apr 1
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