LanG.CoffmanMD

PubMed

• Alternative splice variants of the mitochondrial fission protein/Drp1 regulate mitochondrial dynamics and tumor progression in ovarian cancer.
  Javed, Z., Shin, D., Pan, W., White, S., Kim, Y., Elhaw, A., Kamlapurkar, S., Cheng, Y., Benson, J., Abdelnaby, A., Phaëton, R., Wang, H., Yang, S., Sullivan, M., St C...> ;Biorxiv. 2024 Jan 24
• Stromal-Modulated Epithelial-to-Mesenchymal Transition in Cancer Cells.
  Huda I Atiya, Grace Gorecki, Geyon L Garcia, Leonard G Frisbie, Roja Baruwal, Lan Coffman> ;Biomolecules. 2023 Nov 1
• 2 citations
  Insights into the tumor-stromal-immune cell metabolism cross talk in ovarian cancer.
  Priscilla W Tang, Leonard Frisbie, Nadine Hempel, Lan Coffman> ;American Journal of Physiology. Cell Physiology. 2023 Sep 1
• 2 citations
  The role of adjuvant treatment for early-stage uterine clear cell carcinomas.
  T J Orellana, A A Garrett, T R Soong, T Rives, M Courtney-Brooks, S E Taylor, J Lesnock, J Berger, M Boisen, L Coffman, R Buckanovich, H Mahdi, J C Comerci, S Beriwal,...> ;Gynecologic Oncology. 2023 Mar 1
• 1 citations
  Clinical factors associated with failed sentinel lymph node mapping in endometrial cancer.
  Alison A Garrett, Alyssa Wield, Brigid Mumford, Isabel Janmey, Li Wang, Philip Grosse, Emily MacArthur, Ronald Buckanovich, Madeleine Courtney-Brooks, Paniti Sukumvani...> ;Gynecologic Oncology Reports. 2022 Dec 1
• 10 citations
  Endometriosis-Associated Mesenchymal Stem Cells Support Ovarian Clear Cell Carcinoma through Iron Regulation.
  Huda I Atiya, Leonard Frisbie, Ester Goldfeld, Taylor Orellana, Nicole Donnellan, Francesmary Modugno, Michael Calderon, Simon Watkins, Rugang Zhang, Esther Elishaev, ...> ;Cancer Research. 2022 Dec 16
• 7 citations
  Call for action: expanding global access to hereditary cancer genetic testing.
  Brittany Bychkovsky, Huma Q Rana, Foluso Ademuyiwa, Jennifer Plichta, Karen Anderson, Angélica Nogueira-Rodrigues, Cesar A Santa-Maria, Lan G Coffman, Carol Marquez, A...> ;The Lancet. Oncology. 2022 Sep 1
• 6 citations
  Phase I trial of ribociclib with platinum chemotherapy in ovarian cancer.
  Lan G Coffman, Taylor J Orellana, Tianshi Liu, Leonard G Frisbie, Daniel Normolle, Kent Griffith, Shitanshu Uppal, Karen McLean, Jessica Berger, Michelle Boisen, Madel...> ;JCI Insight. 2022 Sep 22
• 27 citations
  Carcinoma-Associated Mesenchymal Stem/Stromal Cells: Architects of the Pro-tumorigenic Tumor Microenvironment.
  Len Frisbie, Ronald J Buckanovich, Lan Coffman> ;Stem Cells. 2022 Aug 25
• 5 citations
  Shifting the Soil: Metformin Treatment Decreases the Protumorigenic Tumor Microenvironment in Epithelial Ovarian Cancer.
  Sarah E Taylor, Daniel K Chan, Dongli Yang, Tulia Bruno, Richard Lieberman, Javed Siddiqui, Thing Rinda Soong, Lan Coffman, Ronald J Buckanovich> ;Cancers. 2022 May 5
• 4 citations
  Novel Therapies in Gynecologic Cancer.
  Francisco Grau Bejar, Ana Oaknin, Casey Williamson, Jyoti Mayadev, Pamela N Peters, Angeles Alvarez Secord, Alyssa M Wield, Lan G Coffman> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2022 Apr 1
• 6 citations
  Metformin and survival: Is there benefit in a cohort limited to diabetic women with endometrial, breast, or ovarian cancer?
  Lara S Lemon, Brian Orr, Francesmary Modugno, Ronald J Buckanovich, Lan Coffman, Robert P Edwards, Sarah Taylor> ;Gynecologic Oncology. 2022 Apr 1
• 16 citations
  Prevalence of intratumoral regulatory T cells expressing neuropilin-1 is associated with poorer outcomes in patients with cancer.
  Christopher A Chuckran, Anthony R Cillo, Jessica Moskovitz, Abigail Overacre-Delgoffe, Ashwin S Somasundaram, Feng Shan, Grant C Magnon, Sheryl R Kunning, Irina Abecas...> ;Science Translational Medicine. 2021 Dec 8
• 31 citations
  Cancer-associated MSC drive tumor immune exclusion and resistance to immunotherapy, which can be overcome by Hedgehog inhibition
  Sandra Cascio, Chelsea Chandler, Linan Zhang, Sarah Sinno, Bingsi Gao, Sayali Onkar, Tullia C. Bruno, Dario A. A. Vignali, Haider Mahdi, Hatice U. Osmanbeyoglu, Anda M...> ;Science Advances. 2021 Nov 12
• 7 citations
  Cost-effectiveness analysis of tumor molecular classification in high-risk early-stage endometrial cancer.
  Taylor Orellana, Hyun Soo Kim, Sushil Beriwal, Rohit Bhargava, Jessica Berger, Ronald J. Buckanovich, Lan G. Coffman, Madeleine Courtney-Brooks, H. Mahdi, Alexander B....> ;Gynecologic Oncology. 2021 Nov 2
• 123 citations
  B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma
  Ayana T. Ruffin, Anthony R. Cillo, Tracy Tabib, Angen Liu, Sayali Onkar, Sheryl Kunning, Caleb Lampenfeld, Huda Atiya, Irina Abecassis, Cornelius H. L. Kürten, Zengbia...> ;Nature Communications. 2021 Jun 7
• 2 citations
  An Orthotopic Mouse Model of Ovarian Cancer using Human Stroma to Promote Metastasis.
  Huda Atiya, Taylor Orellana, Alyssa Wield, Leonard Frisbie, Lan G. Coffman> ;Journal of Visualized Experiments. 2021 Mar 23
• 28 citations
  Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis
  Huihui Fan, Huda Atiya, Yeh Wang, Thomas R. Pisanic, Tza-Huei Wang, Ie Ming Shih, Kelly K. Foy, Leonard Frisbie, Ronald J. Buckanovich, Alison A. Chomiak, Rochelle L. ...> ;Cell Reports. 2020 Dec 8
• 101 citations
  Phase II clinical trial of metformin as a cancer stem cell–targeting agent in ovarian cancer
  Jason Brown, Daniel K Chan, Jessica J. Shank, Kent A. Griffith, Huihui Fan, Robert Szulawski, Kun Yang, R. Kevin Reynolds, Carolyn Johnston, Karen McLean, Shitanshu Up...> ;JCI Insight. 2020 Jun 4
• 46 citations
  Mesenchymal Stem Cells in the Tumor Microenvironment.
  Huda Atiya, Leonard Frisbie, Catherine A. Pressimone, Lan G. Coffman> ;Advances in Experimental Medicine and Biology. 2020 Jan 1
• 17 citations
  CD105 Is Expressed in Ovarian Cancer Precursor Lesions and Is Required for Metastasis to the Ovary.
  Shoumei Bai, Wanhong Zhu, Lan G. Coffman, Anda M. Vlad, Lauren E. Schwartz, Esther Elishaev, Ronny Drapkin, Ronald J. Buckanovich> ;Cancers. 2019 Nov 2
• 112 citations
  The double edge sword of fibrosis in cancer
  Chelsea Chandler, Tianshi Liu, Ronald J. Buckanovich, Lan G. Coffman> ;Translational Research. 2019 Jul 1
• 53 citations
  Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth
  Karen McLean, Lijun Tan, Danielle E. Bolland, Lan G. Coffman, Luke F. Peterson, Moshe Talpaz, Nouri Neamati, Ronald J. Buckanovich> ;Oncogene. 2019 Feb 28
• 52 citations
  Ovarian Carcinoma-Associated Mesenchymal Stem Cells Arise from Tissue-Specific Normal Stroma.
  Lan G. Coffman, Alexander T. Pearson, Leonard Frisbie, Zachary T. Freeman, Elizabeth L. Christie, David D.L. Bowtell, Ronald J. Buckanovich> ;Stem Cells. 2019 Feb 1
• 40 citations
  CDK4/6 inhibition as maintenance and combination therapy for high grade serous ovarian cancer
  Mangala Iyengar, Patrick O'Hayer, Alexander J. Cole, Tara Sebastian, Kun Yang, Lan G. Coffman, Ronald J. Buckanovich> ;Oncotarget. 2018 Feb 26
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