LeeSCohenMD

Psychiatry • Boston, MA

Edmund and Carroll Carpenter Professor of Psychiatry , Massachusetts General Hospital, Harvard Medical School

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Office
185 Cambridge Street
Suite 220
Boston, MA 02114
Phone+1 617-724-5600

Fax+1 617-643-3080
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Education & Training

Massachusetts General Hospital/McLean HospitalResidency, Psychiatry, 1984 - 1986
St Elizabeth's Medical CenterInternship, Internal Medicine, 1983 - 1984
Albany Medical CollegeClass of 1983

Certifications & Licensure

MA State Medical License 1984 - 2025
American Board of Psychiatry and Neurology Psychiatry

Clinical Trials

Bipolar Disorder in Pregnancy and the Postpartum Period: Predictors of Morbidity Start of enrollment: 2005 Aug 01
The Treatment of Insomnia in Symptomatic Peri- and Postmenopausal Women Start of enrollment: 2006 Feb 01
Completed
Not Applicable
The Oral Contraceptive Pill for Premenstrual Worsening of Depression Start of enrollment: 2008 Feb 01
Completed
Not Applicable
Omega-3 for Peri- and Postmenopausal Depression Start of enrollment: 2008 Nov 01
Completed
Not Applicable
MsFLASH-02: Interventions for Relief of Menopausal Symptoms: A 3-by-2 Factorial Design Examining Yoga, Exercise, and Omega-3 Supplementation Start of enrollment: 2010 Nov 01
Completed
Not Applicable
National Pregnancy Registry for Psychiatric Medications Start of enrollment: 2008 Nov 01
Recruiting
MsFLASH-03: Comparative Efficacy of Low-Dose Estradiol and Venlafaxine XR for Treatment of Menopausal Symptoms Start of enrollment: 2011 Nov 01
Completed
Not Applicable
Cognitive-Behavioral Therapy (CBT) in Women Discontinuing Antidepressant for Pregnancy Start of enrollment: 2008 Nov 01
Completed
Not Applicable
Symptom Tracking in Assisted Reproductive Technologies Start of enrollment: 2012 Oct 01
Completed
Gabapentin for Insomnia Symptoms and Nighttime Vasomotor Symptoms (VMS) in Peri- and Postmenopausal Women Start of enrollment: 2014 Jan 01
Completed
Not Applicable
Vortioxetine for Menopausal Depression Start of enrollment: 2015 Jun 12
Completed
Phase 4
Preventing Depressive Relapse in Pregnant Women With Recurrent Depression Start of enrollment: 2019 Mar 12
Completed
Not Applicable
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Publications & Presentations

PubMed

Effects of Prenatal Exposure to Second-Generation Antipsychotics on Development and Behavior Among Preschool-Aged Children: Preliminary Results From the National Pregn...
Carol Swetlik, Lee S Cohen, Lauren A Kobylski, Ellen T Sojka, Parker C Killenberg, Marlene P Freeman, Adele C Viguera> ;The Journal of Clinical Psychiatry. 2024 Mar 13
1 citations
The lived experiences of individuals with postpartum psychosis: A qualitative analysis.
Vanderkruik, R., Kobylski, L., Dunk, M., Arakelian, M., Gaw, M., Dineen, H., Kanamori, M., Freeman, M., Cohen, L.> ;Journal of Affective Disorders. 2024 Mar 1
Stressors and coping mechanisms among pregnant women with psychiatric disorders during the COVID-19 pandemic.
Rebecca S Hock, Anna Feeney, Heather A Harmon, Phoebe S Caplin, Lauren A Kobylski, Ella T Rossa, Adele C Viguera, Lee S Cohen, Marlene P Freeman> ;Annals of Clinical Psychiatry. 2023 Aug 1
1 citations
The Challenge of Clinical Research and Suicidality: Participant Feedback on a Safety Protocol.
Rachel Vanderkruik, Marlene P Freeman, Katherine A Dunn, Charlotte A Clifford, Sona Dimidjian, Lee S Cohen> ;The Journal of Clinical Psychiatry. 2023 May 15
To screen or not to screen: Are we asking the right question? In response to considering de-implementation of universal perinatal depression screening.
Rachel Vanderkruik, Marlene P Freeman, Ruta Nonacs, Michael Jellinek, Margaret L Gaw, Charlotte A Clifford, Stephen Bartels, Lee S Cohen> ;General Hospital Psychiatry. 2023 Apr 23
Risk of Major Malformations Following First-Trimester Exposure to Olanzapine: Preliminary Data From the Massachusetts General Hospital National Pregnancy Registry for ...
Adele C Viguera, Marlene P Freeman, Lauren A Kobylski, Ella T Rossa, Peter Gaccione, David Chitayat, Sonia Hernández-Díaz, Lee S Cohen> ;Journal of Clinical Psychopharmacology. 2023 Feb 24
2 citations
Risk of Poor Neonatal Adaptation Syndrome Among Infants Exposed to Second-Generation Atypical Antipsychotics Compared to Antidepressants: Results From the National Pre...
Adele C Viguera, Sara A McElheny, Phoebe S Caplin, Lauren A Kobylski, Ella T Rossa, Amanda V Young, Peter Gaccione, Lina Góez-Mogollón, Marlene P Freeman, Lee S Cohen> ;The Journal of Clinical Psychiatry. 2023 Jan 4
2 citations
Establishment of the MGH Postpartum Psychosis Project: MGHP3.
Lee S Cohen, Rachel Vanderkruik, Miranda Arakelian, Taylor R Church, Madison M Dunk, Marlene P Freeman> ;Plos One. 2023 Jan 1
2 citations
Risk of major malformations in infants after first-trimester exposure to benzodiazepines: Results from the Massachusetts General Hospital National Pregnancy Registry f...
Mercedes J Szpunar, Marlene P Freeman, Lauren A Kobylski, Phoebe S Caplin, Peter Gaccione, Adele C Viguera, David Chitayat, Sonia Hernández-Díaz, Lee S Cohen> ;Depression and Anxiety. 2022 Dec 1
Neurobehavioral follow-up of children exposed to selective serotonin reuptake inhibitors in utero.
Lee S Cohen, Sinéad M Rhodes, Lauren D Claypoole, Lina Góez-Mogollón, Alexandra Z Sosinsky, Danna Moustafa, Olivia B Noe, Sara A McElheny, Laura J Cheng, Johanna R Bic...> ;Annals of Clinical Psychiatry. 2022 Aug 1
5 citations
Body dissatisfaction and disordered eating in the perinatal period: an underrecognized high-risk timeframe and the opportunity to intervene.
Rachel Vanderkruik, Kalin Ellison, Margaux Kanamori, Marlene P Freeman, Lee S Cohen, Eric Stice> ;Archives of Women's Mental Health. 2022 Aug 1
1 citations
Perinatal experiences of pregnant women with psychiatric disorders during the COVID-19 pandemic.
Anna Feeney, Rebecca S. Hock, Heather A Harmon, Phoebe S. Caplin, Lauren A Kobylski, Adele C. Viguera, Marlene P. Freeman, Lee S. Cohen> ;General Hospital Psychiatry. 2021 Nov 6
3 citations
Postpartum depression screening: Treatment engagement, barriers to care, and change in depressive symptoms.
Rachel Vanderkruik, Marlene P. Freeman, Lauren D. Claypoole, Miranda Arakelian, Anjali J Kaimal, Hiyam Nadel, Lee S. Cohen> ;Annals of Clinical Psychiatry. 2021 Nov 1
Correction. Reproductive Safety of Second-Generation Antipsychotics: Updated Data From the Massachusetts General Hospital National Pregnancy Registry for Atypical Anti...
Adele C Viguera, Marlene P Freeman, Lina Góez-Mogollón, Alexandra Z Sosinsky, Sara A McElheny, Taylor R Church, Amanda V Young, Phoebe S Caplin, David Chitayat, Sonia ...> ;The Journal of Clinical Psychiatry. 2021 Oct 5
3 citations
Perinatal depression screening using smartphone technology: Exploring uptake, engagement and future directions for the MGH Perinatal Depression Scale (MGHPDS).
Rachel Vanderkruik, Edwin R. Raffi, Marlene P. Freeman, Rebecca Wales, Lee S. Cohen> ;Plos One. 2021 Sep 29
7 citations
Low barrier perinatal psychiatric care for patients with substance use disorder: meeting patients across the perinatal continuum where they are.
Edwin R. Raffi, Jessica Gray, Nkechi Conteh, Martha Kane, Lee S. Cohen, Davida M. Schiff> ;International Review of Psychiatry. 2021 Aug 18
10 citations
Reproductive Safety of Second-Generation Antipsychotics: Updated Data From the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics.
Adele C Viguera, Marlene P Freeman, Lina Góez-Mogollón, Alexandra Z Sosinsky, Sara A McElheny, Taylor R Church, Amanda V Young, Phoebe S Caplin, David Chitayat, Sonia ...> ;The Journal of Clinical Psychiatry. 2021 Aug 3
1 citations
Breastfeeding practices among women taking second-generation antipsychotics: findings from the National Pregnancy Registry for Atypical Antipsychotics.
Adele C. Viguera, Rachel Vanderkruik, Peter Gaccione, Phoebe S. Caplin, Lauren A Kobylski, Marlene P. Freeman, Lee S. Cohen> ;Archives of Women's Mental Health. 2021 Jul 28
15 citations
Association of adverse prenatal exposure burden with child psychopathology in the Adolescent Brain Cognitive Development (ABCD) Study.
Joshua L. Roffman, Eren D. Sipahi, Kevin F. Dowling, Dylan Hughes, Casey Hopkinson, Hang Lee, Hamdi Eryilmaz, Lee S. Cohen, Jodi M. Gilman, Alysa E. Doyle, Erin C. Dunn> ;Plos One. 2021 Apr 28
Correction to: Reproductive safety of aripiprazole: data from the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics.
Marlene P Freeman, Adele C Viguera, Lina Góez-Mogollón, Amanda V Young, Phoebe S Caplin, Sara A McElheny, Taylor R Church, David Chitayat, Sonia Hernández-Díaz, Lee S ...> ;Archives of Women's Mental Health. 2021 Aug 1
7 citations
Reproductive safety of aripiprazole: data from the Massachusetts General Hospital National Pregnancy Registry for Atypical Antipsychotics.
Marlene P Freeman, Adele C Viguera, Lina Góez-Mogollón, Amanda V Young, Phoebe S Caplin, Sara A McElheny, Taylor R Church, David Chitayat, Sonia Hernández-Díaz, Lee S ...> ;Archives of Women's Mental Health. 2021 Aug 1
9 citations
The safety of asthma medications during pregnancy and lactation: Clinical management and research priorities.
Christina D. Chambers, Jerry A. Krishnan, Lorene Alba, Jessica D. Albano, Allison S. Bryant, Melanie Carver, Lee S. Cohen, Elena Gorodetsky, Sonia Hernandez-Diaz, Marg...> ;The Journal of Allergy and Clinical Immunology. 2021 Jun 1
Challenges in Determining Outcomes of Prenatal Exposure to Antidepressants
Ruta Nonacs, Lee S. Cohen> ;The Journal of Clinical Psychiatry. 2020 May 12
23 citations
Impact of Estradiol Variability and Progesterone on Mood in Perimenopausal Women With Depressive Symptoms
Hadine Joffe, Anouk E. de Wit, Jamie E. Coborn, Sybil L. Crawford, Marlene P. Freeman, Aleta Wiley, Geena Athappilly, Semmie Kim, Kathryn Sullivan, Lee S. Cohen, Janet...> ;The Journal of Clinical Endocrinology and Metabolism. 2020 Mar 1
15 citations
Lights on MsFLASH: a review of contributions.
Susan D. Reed, Andrea Z. LaCroix, Garnet L. Anderson, Kristine E. Ensrud, Bette J. Caan, Janet S. Carpenter, Lee S. Cohen, Susan J. Diem, Ellen W. Freeman, Hadine Joff...> ;Menopause. 2020 Apr 1
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Journal Articles

Course of Major Depressive Disorder After Pregnancy and the Postpartum Period
Lee S Cohen, Vivien K Burt, Marlene P Freeman, Danna Moustafa, Depression and Anxiety

Hospital Affiliations

Massachusetts General HospitalBoston, Massachusetts