GustavoDKinrysMD

Psychiatry • Boston, MA

Psychopharmacology, Clinical Pharmacology, Clinical Informatics

Medical Director

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Office
50 Staniford Street
Suite 580
Boston, MA 02114
Phone+1 617-643-6257

Fax+1 617-726-6768
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Education & Training

Massachusetts General HospitalFellowship, Research, 2001 - 2003
Massachusetts General Hospital/McLean HospitalChief Residency, Psychiatry, 2000 - 2002
Mayo Clinic College of Medicine and Science (Rochester)Residency, Psychiatry, 1998 - 2002
Faculdade de Medicina da Universidade Federal do Rio de JaneiroClass of 1996

Certifications & Licensure

MA State Medical License 2001 - 2024
MN State Medical License 2001 - 2002

Clinical Trials

rEEG Guided Pharmacotherapy of Subjects With Depression Treatment Failure Start of enrollment: 2006 Aug 01
Completed
Not Applicable
A 12-Week, Placebo Controlled Trial of Ziprasidone as Monotherapy for Major Depressive Disorder Start of enrollment: 2008 Mar 01
Completed
Phase 2
Adjunctive Quetiapine in the Treatment of Refractory Social Anxiety Disorder in Adults Start of enrollment: 2006 Mar 01
Completed
Phase 4
A Paroxetine- and Placebo-Controlled Study of 50 mg/Day and 100 mg/Day of EB-1010 Among Outpatients With Major Depressive Disorder Who Have Responded Inadequately to Prior Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin Norepinephrine Reuptake Inhibitors (SNRIs) Start of enrollment: 2011 Feb 01
Completed
Phase 2, Phase 3
Suvorexant (Belsomra) for the Treatment of Bipolar Depression With Insomnia Start of enrollment: 2019 Feb 26
Withdrawn
Phase 4
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Publications & Presentations

PubMed

4 citations
Psychotic symptoms during bipolar depressive episodes and suicidal ideation.
Maya Kuperberg, Douglas I. Katz, Sophie L. A. Greenebaum, Nevita George, Louisa G. Sylvia, Gustavo Kinrys, Astrid Desrosiers, Andrew A. Nierenberg> ;Journal of Affective Disorders. 2021 Mar 1
6 citations
An evaluation of suicidal risk in bipolar patients with comorbid posttraumatic stress disorder.
Douglas I. Katz, Timothy Petersen, Selen Amado, Maya Kuperberg, Steven Dufour, Marina Rakhilin, Nathan Hall, Gustavo Kinrys, Astrid Desrosiers, Thilo Deckersbach, Loui...> ;Journal of Affective Disorders. 2020 Apr 1
10 citations
Bipolar depression and suicidal ideation: Moderators and mediators of a complex relationship.
Masoud Kamali, Noreen A. Reilly-Harrington, Weilynn C. Chang, Melvin G. McInnis, Susan L. McElroy, Terence A. Ketter, Richard C. Shelton, Thilo Deckersbach, Mauricio T...> ;Journal of Affective Disorders. 2019 Dec 1
24 citations
Clinical applications of transcranial magnetic stimulation in bipolar disorder.
Alexandra K. Gold, Ana Claudia Ornelas, Patricia Cirillo, Marco Antonio Knob Caldieraro, Antonio Egidio Nardi, Andrew A. Nierenberg, Gustavo Kinrys> ;Brain and Behavior. 2019 Sep 30
70 citations
Transcranial magnetic stimulation in anxiety and trauma-related disorders: A systematic review and meta-analysis.
Patricia Cirillo, Alexandra K. Gold, Antonio Egidio Nardi, Ana Claudia Ornelas, Andrew A. Nierenberg, Joan A. Camprodon, Gustavo Kinrys> ;Brain and Behavior. 2019 Jun 1
40 citations
Treating Circadian Rhythm Disruption in Bipolar Disorder.
Alexandra K. Gold, Gustavo Kinrys> ;Current Psychiatry Reports. 2019 Mar 2
7 citations
Comorbid anxiety in bipolar CHOICE: Insights from the bipolar inventory of symptoms scale.
Gustavo Kinrys, Charles L. Bowden, Andrew A. Nierenberg, Casey M. Hearing, Alexandra K. Gold, Dustin J. Rabideau, Louisa G. Sylvia, Keming Gao, Masoud Kamali, William ...> ;Journal of Affective Disorders. 2019 Mar 1
19 citations
Tachyphylaxis in major depressive disorder: A review of the current state of research.
Gustavo Kinrys, Alexandra K. Gold, Vincent D. Pisano, Marlene P. Freeman, George I. Papakostas, David Mischoulon, Andrew A. Nierenberg, Maurizio Fava> ;Journal of Affective Disorders. 2019 Feb 15
11 citations
The impact of binge eating behavior on lithium- and quetiapine-associated changes in body weight, body mass index, and waist circumference during 6 months of treatment...
Satyanarayana R. Yaramala, Susan L. McElroy, Jennifer R. Geske, Stacey J. Winham, Keming Gao, Noreen A. Reilly-Harrington, Terence A. Ketter, Thilo Deckersbach, Gustav...> ;Journal of Affective Disorders. 2020 Apr 1
28 citations
Substance use comorbidity in bipolar disorder: A qualitative review of treatment strategies and outcomes.
Alexandra K. Gold, Michael W. Otto, Thilo Deckersbach, Louisa G. Sylvia, Andrew A. Nierenberg, Gustavo Kinrys> ;The American Journal on Addictions. 2018 Apr 1
27 citations
Medication disposal practices: Increasing patient and clinician education on safe methods.
Gustavo Kinrys, Alexandra K. Gold, John J. Worthington, Andrew A. Nierenberg> ;The Journal of International Medical Research. 2018 Jan 11
16 citations
Sleep disturbance may impact treatment outcome in bipolar disorder: A preliminary investigation in the context of a large comparative effectiveness trial.
Louisa G. Sylvia, Weilynn C. Chang, Masoud Kamali, Mauricio Tohen, Gustavo Kinrys, Thilo Deckersbach, Joseph R. Calabrese, Michael E. Thase, Noreen A. Reilly-Harringto...> ;Journal of Affective Disorders. 2018 Jan 1
17 citations
L-Methylfolate For Bipolar I depressive episodes: An open trial proof-of-concept registry.
Andrew A. Nierenberg, Rebecca E. Montana, Gustavo Kinrys, Thilo Deckersbach, Steven Dufour, Ji Hyun Baek> ;Journal of Affective Disorders. 2017 Jan 1
6 citations
Tracking medication changes to assess outcomes in comparative effectiveness research: A bipolar CHOICE study.
Noreen A. Reilly-Harrington, Louisa G. Sylvia, Dustin J. Rabideau, Alexandra K. Gold, Thilo Deckersbach, Charles L. Bowden, William V. Bobo, Vivek Singh, Joseph R. Cal...> ;Journal of Affective Disorders. 2016 Nov 15
A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients.
Fava M, Johe K, Ereshefsky L, Gertsik LG, English BA, Bilello JA, Thurmond LM, Johnstone J, Dickerson BC, Makris N, Hoeppner BB, Flynn M, Mischoulon D, Kinrys G, Freem...> ;Mol. Psychiatry. 2016-10-01
20 citations
A tool to predict suicidal ideation and behavior in bipolar disorder: The Concise Health Risk Tracking Self-Report
Noreen A. Reilly-Harrington, Richard C. Shelton, Masoud Kamali, Dustin J. Rabideau, Leah W. Shesler, Madhukar H. Trivedi, Susan L. McElroy, Louisa G. Sylvia, Charles L...> ;Journal of Affective Disorders. 2016 Mar 1
40 citations
Obesity, but not metabolic syndrome, negatively affects outcome in bipolar disorder
Susan L. McElroy, David E. Kemp, Edward S. Friedman, Noreen A. Reilly-Harrington, Louisa G. Sylvia, Joseph R. Calabrese, Dustin J. Rabideau, Terence A. Ketter, Michael...> ;Acta Psychiatrica Scandinavica. 2016 Feb 1
17 citations
Baseline disability and poor functioning in bipolar disorder predict worse outcomes: results from the Bipolar CHOICE study.
Thilo Deckersbach, Andrew A. Nierenberg, Melvin G. McInnis, Stephanie Salcedo, Emily E. Bernstein, David E. Kemp, Richard C. Shelton, Susan L. McElroy, Louisa G. Sylvi...> ;The Journal of Clinical Psychiatry. 2016 Jan 27
54 citations
Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness): A Pragmatic 6-Month Trial of Lithium Versus Quetiapine for Bipolar Disorder
Andrew A. Nierenberg, Susan L. McElroy, Edward S. Friedman, Terence A. Ketter, Richard C. Shelton, Thilo Deckersbach, Melvin G. McInnis, Charles L. Bowden, Mauricio To...> ;The Journal of Clinical Psychiatry. 2016 Jan 1
4 citations
A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients.
M Fava, K Johe, L Ereshefsky, L G Gertsik, B A English, J A Bilello, L M Thurmond, J Johnstone, B C Dickerson, N Makris, B B Hoeppner, M Flynn, D Mischoulon, G Kinrys,...> ;Molecular Psychiatry. 2016 Oct 1
60 citations
Medical burden in bipolar disorder: findings from the Clinical and Health Outcomes Initiative in Comparative Effectiveness for Bipolar Disorder study (Bipolar CHOICE)
Louisa G. Sylvia, Richard C. Shelton, David E. Kemp, Emily E. Bernstein, Edward S. Friedman, Benjamin D. Brody, Susan L. McElroy, Vivek Singh, Mauricio Tohen, Charles ...> ;Bipolar Disorders. 2015 Mar 1
6 citations
Psychotherapy use in bipolar disorder: Association with functioning and illness severity.
Louisa G. Sylvia, Michael E. Thase, Noreen A. Reilly-Harrington, Stephanie Salcedo, Benjamin D. Brody, Gustavo Kinrys, David E. Kemp, Richard C. Shelton, Susan L. McEl...> ;The Australian and New Zealand Journal of Psychiatry. 2015 Feb 13
13 citations
A randomized, double-blind, placebo-controlled phase 2 study of the augmentation of a nicotinic acetylcholine receptor partial agonist in depression: is there a relati...
Maurizio Fava, Tanya Ramey, Eve H. Pickering, Gustavo Kinrys, Stacey Boyer, Larry Altstiel> ;Journal of Clinical Psychopharmacology. 2015 Feb 1
15 citations
Complexity of illness and adjunctive benzodiazepine use in outpatients with bipolar i or II disorder results from the bipolar CHOICE study
William V. Bobo, Noreen A. Reilly-Harrington, Terence A. Ketter, Benjamin D. Brody, Gustavo Kinrys, David E. Kemp, Richard C. Shelton, Susan L. McElroy, Louisa G. Sylv...> ;Journal of Clinical Psychopharmacology. 2015 Feb 1
Corrigendum to "Effect of adjunctive benzodiazepines on clinical outcomes in lithium- or quetiapine-treated outpatients with bipolar I or II disorder: Results from the...
Bobo, W. V.,Reilly-Harrington, N. A.,Ketter, T. A.,Brody, B. D.,Kinrys, G.,Kemp, D. E.,Shelton, R. C.,McElroy, S. L.,Sylvia, L. G.,Kocsis, J. H.,McInnis, M. G.,Friedma...> ;J Affect Disord. 2014 Jul 08
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Journal Articles

Research Paper Tachyphylaxis in Major Depressive Disorder: A Review of the Current State of Research
Gustavo Kinrys, Andrew A Nierenberg, George I Papakostas, David Mischoulon, Maurizio Fava, Marlene P Freeman, ScienceDirect

Press Mentions

Demand for Virtual Mental Healthcare Is Soaring. Here Are Key Trends on Who Is Using It and WhyOctober 23rd, 2020
Teladoc Health Data Shows Broadening Mental Health Care DemandOctober 21st, 2020
Antidepressant with Novel Mechanism of Action Appears Safe and Effective in Phase 1b Clinical TrialDecember 8th, 2015