LeslieVBoyerMDFACMT

Pediatrics • Tucson, AZ

Medical Toxicology

Professor Emerita, Pathology, University of Arizona College of Medicine

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Office
1501 N Campbell Ave
Tucson, AZ 85724
Phone+1 520-874-3500
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Education & Training

University of Arizona College of Medicine-TucsonFellowship, Medical Toxicology (Emergency Medicine), 1989 - 1991
University of Arizona College of Medicine-TucsonChief Residency, Pediatrics, 1988 - 1989
University of Arizona College of Medicine-TucsonResidency, Pediatrics, 1987 - 1988
Children's Hospital/Boston Medical CenterResidency, Pediatrics, 1985 - 1987
Harvard Medical SchoolClass of 1985

Certifications & Licensure

AZ State Medical License 1989 - 2026
American Board of Medical ToxicologyMedical Toxicology

Clinical Trials

Treatment Protocol for Use of Anascorp™ in Patients With Scorpion Sting Envenomation Start of enrollment: 2005 May 01
Completed
Phase 2, Phase 3
Double-Blind, Alacramyn® vs. Placebo in Pediatric Patients Start of enrollment: 2004 May 01
Completed
Phase 2, Phase 3
A Comparison of Crotalinae Equine Immune F(ab)2 Antivenom (Anavip) and Crotalidae Polyvalent Immune Fab, Start of enrollment: 2005 Jan 01
Completed
Phase 2
A Trial of Equine F (ab')2 Antivenom for Treatment of Scorpion Envenomation in Morocco Start of enrollment: 2018 Jul 21
Completed
Phase 2, Phase 3
Emergency Treatment of Coral Snake Envenomation With Antivenom Start of enrollment: 2012 May 01
Completed
Phase 3
Open Label Study of Alacramyn® in Pediatric Patients With Scorpion Sting Envenomation Start of enrollment: 2005 May 01
Completed
Phase 3
Open Label Clinical Trial of Anascorp® in Pediatric Patients With Scorpion Sting Envenomation Start of enrollment: 2004 Apr 01
Completed
Phase 3
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Publications & Presentations

PubMed

10 citations
Single-Arm, Multicenter Phase I/II Clinical Trial for the Treatment of Envenomings by Massive Africanized Honey Bee Stings Using the Unique Apilic Antivenom
Alexandre Naime Barbosa, Rui Seabra Ferreira, Francilene Capel Tavares de Carvalho, Fabiana Schuelter-Trevisol, Mônica Bannwart Mendes, Bruna Cavecci Mendonça, José Ni...> ;Frontiers in Immunology. 2021 Mar 23
10 citations
Neotropical rattlesnake (Crotalus simus) venom pharmacokinetics in lymph and blood using an ovine model
Edgar Neri-Castro, Melisa Bénard-Valle, Dayanira Paniagua, Leslie V. Boyer, Lourival D. Possani, Fernando López-Casillas, Alejandro Olvera, Camilo Romero, Fernando Z. ...> ;Toxins. 2020 Jul 17
12 citations
Snake bites and antivenom shortage in Africa
Jean-Philippe Chippaux, Achille Massougbodji, Amadou Diouf, C. Balde, Leslie V. Boyer> ;Lancet. 2015 Dec 5
17 citations
Thrombelastographic characterization of the thrombin-like activity of Crotalus simus and Bothrops asper venoms.
Vance G. Nielsen, Leslie V. Boyer, Daniel T. Redford, Paul M. Ford> ;Blood Coagulation & Fibrinolysis. 2017 Apr 1
4 citations
Iron and carbon monoxide attenuate Crotalus atrox venom-enhanced tissue-type plasminogen activator-initiated fibrinolysis.
Vance G. Nielsen, Leslie V. Boyer, Ryan W. Matika, Quinlan Amos, Daniel T. Redford> ;Blood Coagulation & Fibrinolysis. 2016 Jul 1
15 citations
Iron and carbon monoxide attenuate degradation of plasmatic coagulation by Crotalus atrox venom.
Vance G. Nielsen, Leslie V. Boyer> ;Blood Coagulation & Fibrinolysis. 2016 Jul 1
15 citations
Antivenom effect on lymphatic absorption and pharmacokinetics of coral snake venom using a large animal model.
Dayanira Paniagua, Irene Vergara, R. Roman, Camilo Romero, Melisa Bénard-Valle, Arlene Calderón, Lucía Jiménez, Michael Bernas, Marlys H. Witte, Leslie V. Boyer, Aleja...> ;Clinical Toxicology. 2019 Feb 18
18 citations
The Bold and the Beautiful: a Neurotoxicity Comparison of New World Coral Snakes in the Micruroides and Micrurus Genera and Relative Neutralization by Antivenom
Daryl C. Yang, James Dobson, Chip Cochran, Daniel Dashevsky, Kevin Arbuckle, Melisa Benard, Leslie V. Boyer, Alejandro Alagón, Iwan Hendrikx, Wayne C. Hodgson, Bryan G...> ;Neurotoxicity Research. 2017 Jul 3
39 citations
A clinical trial protocol to treat massive Africanized honeybee ( Apis mellifera ) attack with a new apilic antivenom
Alexandre Naime Barbosa, Leslie V. Boyer, Jean-Philippe Chippaux, Natália Bronzatto Medolago, Carlos Antonio Caramori, Ariane Gomes Paixão, João Paulo Vasconcelos Poli...> ;The Journal of Venomous Animals and Toxins Including Tropical Diseases. 2017 Mar 16
7 citations
Venom yield and its relationship with body size and fang separation of pit vipers from Argentina
Adolfo Rafael de Roodt, Leslie V. Boyer, Laura Cecilia Lanari, Lucia Irazu, Rodrigo Daniel Laskowicz, Paula Leticia Sabattini, Carlos Fabián Damin> ;Toxicon. 2016 Oct 1
The Reply.
Boyer LV> ;Am. J. Med.. 2016-06-01
2 citations
Pitviper Envenomation Guidelines Should Address Choice Between FDA-approved Treatments for Cases at Risk of Late Coagulopathy
Leslie V. Boyer, Anne Michelle Ruha> ;Wilderness & Environmental Medicine. 2016 Jun 1
7 citations
Biodistribution and Lymphatic Tracking of the Main Neurotoxin of Micrurus fulvius Venom by Molecular Imaging.
Irene Vergara, Erick Y. Castillo, Mario E. Romero-Piña, Itzel Torres-Viquez, Dayanira Paniagua, Leslie V. Boyer, Alejandro Alagón, Luis A. Medina> ;Toxins. 2016 Mar 26
11 citations
On 1000-Fold Pharmaceutical Price Markups and Why Drugs Cost More in the United States than in Mexico
Leslie V. Boyer> ;The American Journal of Medicine. 2015 Dec 1
In Reply re: "Comparison of F(ab')2 versus Fab antivenom for Pit Viper Envenomation: A Prospective, Blinded, Multicenter, Randomized Clinical Trial".
Bush, S. P.,Ruha, A. M.,Seifert, S. A.,Sollee, D. R.,Boyer, L. V.> ;Clin Toxicol (Phila). 2015 Feb 24
7 citations
Post-exposure treatment of Ebola virus using passive immunotherapy: proposal for a new strategy
Jean-Philippe Chippaux, Leslie V. Boyer, Alejandro Alagón> ;The Journal of Venomous Animals and Toxins Including Tropical Diseases. 2015 Feb 15
43 citations
Comparison of F(ab')2 versus Fab antivenom for pit viper envenomation: a prospective, blinded, multicenter, randomized clinical trial.
Sean P Bush, Anne-Michelle Ruha, Steven A Seifert, David L Morgan, Brandon J Lewis, Thomas C Arnold, Richard F Clark, William J Meggs, Eric A Toschlog, Stephen W Borro...> ;Clinical Toxicology. 2015 Jan 1
14 citations
Is scorpion antivenom cost-effective as marketed in the United States?
Edward P. Armstrong, Maja Bakall, Grant H. Skrepnek, Leslie V. Boyer> ;Toxicon. 2013 Dec 15
23 citations
Non-Native (Exotic) Snake Envenomations in the U.S., 2005–2011
Brandon J. Warrick, Leslie V. Boyer, Steven A. Seifert> ;Toxins. 2014 Sep 29
5 citations
Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops (Rhinocerophis) alternatus by specific experimental an...
Laura Cecilia Lanari, Alejandro Olvera, Vanessa Costa de Oliveira, Rodrigo Daniel Laskowicz, Leslie V. Boyer, Néstor Lago, Alagon Alejandro, Adolfo Rafael de Roodt> ;Toxicon. 2014 Jul 1
6 citations
Protein content of antivenoms and relationship with their immunochemical reactivity and neutralization assays
A.R. de Roodt, Herlinda Clement, Jorge A. Dolab, Silvana Litwin, Silvia E. Hajos, Leslie V. Boyer, Alejandro Alagón> ;Clinical Toxicology. 2014 Jun 18
12 citations
Effectiveness of Centruroides scorpion antivenom compared to historical controls.
Leslie V. Boyer, Andreas A. Theodorou, Peter B. Chase, N. Osnaya, M. Berg, Joanne Mallie, Y. Carbajal, T. de Jesus-Hernandez, Felipe Olvera, Alejandro Alagón> ;Toxicon. 2013 Dec 15
39 citations
Subacute coagulopathy in a randomized, comparative trial of Fab and F(ab')2 antivenoms.
Leslie V. Boyer, Peter B. Chase, Janice A. Degan, Gary R. Figge, Alma Buelna-Romero, Cynthia Luchetti, Alejandro Alagón> ;Toxicon. 2013 Nov 1
Editorial: scorpion venom and antivenom.
Leslie V. Boyer> ;Toxicon. 2013 Dec 15
32 citations
Safety of intravenous equine F(ab')2: insights following clinical trials involving 1534 recipients of scorpion antivenom.
Leslie V. Boyer, Janice A. Degan, Anne Michelle Ruha, Joanne Mallie, Emmanuelle F M Mangin, Alejandro Alagón> ;Toxicon. 2013 Dec 15
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Press Mentions

An ER Doctor’s Search for a Snakebite Drug Might Lead to a COVID-19 TreatmentNovember 6th, 2020
A Pill for Heavy Metal Poisoning May Also Save Snakebite VictimsMay 6th, 2020
Researchers Have Already Grown Miniature Brains and Lungs. Next up: Snake Venom Gland OrganoidsJanuary 23rd, 2020
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External Links

Bloghttp://scorpiondoc.silvrback.com