Lewis A Chodosh MD
Diabetes, Lipid Metabolism
Chairman, Dept of Cancer Biology
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3400 Spruce StFl 1Philadelphia, PA 19104
Phone+1 215-662-2300
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Education & Training
Mass General Brigham/Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 1991 - 1994- Mass General Brigham/Massachusetts General HospitalResidency, Internal Medicine, 1989 - 1991
Harvard Medical SchoolClass of 1989
Certifications & Licensure
MA State Medical License 1991 - 2026
PA State Medical License 1994 - 2026
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2002
Publications & Presentations
PubMed
- Residual Breast Cancer Cells Co-opt SOX5-driven Endochondral Ossification to Maintain Dormancy.Amulya Sreekumar, Eric Blankemeyer, Christopher J Sterner, Tien-Chi Pan, Dhruv K Pant
Biorxiv. 2025-05-10 - Ternary Complex Components Responsible for Rapid LDL Internalization as Biomarkers for Breast Cancer Associated with Proliferation and Early Recurrence.Elizabeth S McDonald, Tien-Chi Pan, Dhruv K Pant, Melissa A Troester, Andrew V Kossenkov
Cancer Research Communications. 2025-02-01 - 12 citationsOsteopontin is a therapeutic target that drives breast cancer recurrence.Yu Gu, Tarek Taifour, Tung Bui, Dongmei Zuo, Alain Pacis
Nature Communications. 2024-10-24
Press Mentions
Keeping Cancer ConqueredMay 20th, 2025- Penn Medicine Researchers Receive $10 Million Grant for Preventing Breast Cancer RecurrenceOctober 23rd, 2023
- Dormant Cancer Cells May 'Reawaken' Due to Change in This Key ProteinDecember 14th, 2021
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Grant Support
- In Vivo Oncogene-Induced Tumorigenesis and EscapeUNIVERSITY OF PENNSYLVANIA2003–2029
- In Vivo Oncogene-Induced Tumorigenesis and EscapeUNIVERSITY OF PENNSYLVANIA2003–2029
- Role Of SNF1 Kinase Hunk In Breast Cancer ProgressionNational Cancer Institute2010–2012
- Minimal Residual Disease And Mechanisms Of Breast Cancer RecurrenceNational Cancer Institute2010–2012
- The Impact Of Exercise And Caloric Restriction On Cancer Recurrence In MiceNational Cancer Institute2011
- Novel PET Imaging Agents For Understanding Glutamine Addiction In CancerNational Cancer Institute2011
- Developmental Research CoreNational Cancer Institute2011
- Survival And Recurrence Of Dormant Cancer CellsNational Cancer Institute2010–2011
- Mechanisms Of Breast Cancer ProgressionNational Cancer Institute2009–2011
- PENN Small Animal Imaging Resource (Penn-Sair)National Cancer Institute2007–2011
- Analysis Of Tumor Dynamics In Progression And MetastasisNational Cancer Institute2004–2009
- Mechanisms Of Progression In C-Myc-Induced Breast CancerNational Cancer Institute2002–2006
- Temporal Analysis Of Mammary CarcinogenesisNational Cancer Institute2003–2005
- Mammary Development And Breast Cancer SusceptibilityNational Cancer Institute2001–2005
- Hunk And Punc Function In Mammary Epithelial BiologyNational Cancer Institute2000–2004
- Temporal Analysis Of Mammary CarcinogenesisNational Cancer Institute2002
- Modulation Of Breast Cancer Susceptibility By Reproductive HistoryNational Cancer Institute1998–2002
- BRCA2 Function In Mammary Epithelial BiologyNational Cancer Institute1998–2002
- BRCA1 And Differentiation And Endocrine Risk FactorNational Cancer Institute1996–2000
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