LijunYangMD

PubMed

• Irisin protected hemopoietic stem cells and improved outcome of severe bone marrow failure.
  Hui Li, Dexiao Kong, Yi Zhao, Xia Liu, Fang Xiao, Xiaoyan Li, Jianting Hu, Yingjie Chen, Shengli Li, Baozhu Wang, Yuan Chen, Yang Jiang, Xiaoli Liu, Xiumei Feng, Yanan...> ;Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 2023 Dec 31
• Analysis of the Diagnosis of Burkitt-Like Lymphoma in a Patient With Atypical Cytogenetics and Molecular Markers.
  Jackson R Brunner, Ellery Altshuler, Li-Jun Yang> ;Cureus. 2022 Aug 1
• 6 citations
  GLP-1 Induces the Expression of FNDC5 Derivatives That Execute Lipolytic Actions
  Hui Li, William Donelan, Fang Wang, Peilan Zhang, Li-Jun Yang, Yousong Ding, Dongqi Tang, Shiwu Li> ;Frontiers in Cell and Developmental Biology. 2021 Nov 11
• Classical Hodgkin Lymphoma Presenting as a Sigmoid Mass
  Heather Caulkins, Alyaa Irhayyim, Lijun Yang> ;Gastroenterology Research. 2021 Jun 1
• Reply to comment on: Nrf2 regulates interferon receptor expression and alters macrophage polarization in lupus
  Shuhong Han, Haoyang Zhuang, Pui Y. Lee, Mingjia Li, Lijun Yang, Peter A. Nigrovic, Westley H. Reeves> ;Arthritis & Rheumatology. 2020 Aug 9
• 14 citations
  NF-E2-Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus.
  Shuhong Han, Haoyang Zhuang, Pui Y. Lee, Mingjia Li, Li-Jun Yang, Peter A. Nigrovic, Westley H. Reeves> ;Arthritis & Rheumatology. 2020 Aug 9
• 2 citations
  Langerhans cell sarcoma of the vulva: Case report and review of the literature.
  Stephanie M Tillit, Semiramis Carbajal-Mamani, Robert A. Zlotecki, Li-Jun Yang, Ashwini Esnakula, Jacqueline Castagno, Joel Cardenas-Goicoechea> ;Gynecologic Oncology Reports. 2020 Apr 15
• 18 citations
  Differential Responsiveness of Monocyte and Macrophage Subsets to Interferon.
  Shuhong Han, Haoyang Zhuang, Pui Y. Lee, Mingjia Li, Li-Jun Yang, Peter A. Nigrovic, Westley H. Reeves> ;Arthritis & Rheumatology. 2020 Jan 1
• 35 citations
  Effects of irisin on the differentiation and browning of human visceral white adipocytes.
  Hui Li, Yuan Zhang, Fang Wang, William Donelan, Melanie Christine Zona, Shiwu Li, Westley H. Reeves, Yousong Ding, Dongqi Tang, Li-Jun Yang> ;American Journal of Translational Research. 2019 Dec 15
• 3 citations
  MIST1, an Inductive Signal for Salivary Amylase in Mesenchymal Stem Cells
  Mahmoud Mona, Rehae Miller, Hui Li, Yun-Jong Park, Raafi Zaman, Li-Jun Yang, Seunghee Cha> ;International Journal of Molecular Sciences. 2019 Feb 12
• 3 citations
  Primary Gastric EBV-positive Diffuse Large B Cell Lymphoma (DLBCL) of the Elderly with Plasmablastic Differentiation
  Ming Hu, Jose G. Trevino, Lijun Yang, Dengfeng Cao, Jinping Lai> ;In Vivo. 2018 Mar 1
• 31 citations
  Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages.
  Shuhong Han, Haoyang Zhuang, Stepan Shumyak, Jingfan Wu, Chao Xie, Hui Li, Li-Jun Yang, Westley H. Reeves> ;Frontiers in Immunology. 2018 Feb 2
• 13 citations
  Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity
  Peilan Zhang, Kunhua Li, Guang Yang, Changqing Xia, Jane E. Polston, Gengnan Li, Shiwu Li, Zhao Lin, Li-Jun Yang, Steven D. Bruner, Yousong Ding> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Aug 22
• 22 citations
  A Novel Subset of Anti-Inflammatory CD138+ Macrophages Is Deficient in Mice with Experimental Lupus.
  Shuhong Han, Haoyang Zhuang, Stepan Shumyak, Jingfan Wu, Hui Li, Li-Jun Yang, Westley H. Reeves> ;Journal of Immunology. 2017 Aug 15
• 37 citations
  Pathogenesis of Diffuse Alveolar Hemorrhage in Murine Lupus
  Haoyang Zhuang, Shuhong Han, Pui Y. Lee, Ravil Khaybullin, Stepan Shumyak, Li Lu, Amina Chatha, Anan B. Afaneh, Yuan Zhang, Chao Xie, Dina C. Nacionales, Lyle L. Molda...> ;Arthritis & Rheumatology. 2017 May 5
• 6 citations
  Uncovering stem cell differentiation factors for salivary gland regeneration by quantitative analysis of differential proteomes
  Yun-Jong Park, Jin Koh, Jin Teak Kwon, Yong-Seok Park, Li-Jun Yang, Seunghee Cha> ;Plos One. 2017 Feb 3
• 15 citations
  A Novel Mechanism for Generating the Interferon Signature in Lupus: Opsonization of Dead Cells by Complement and IgM.
  Haoyang Zhuang, Shuhong Han, Yi Li, Deborah Kienhöfer, Pui Lee, Stepan Shumyak, Richard Meyerholz, Krzysztof Rosadzinski, Danielle Rosner, Annie Chan, Yuan Xu, Mark S....> ;Arthritis & Rheumatology. 2016 Dec 1
• 5 citations
  "Lupoid hepatitis" in SLE patients and mice with experimental lupus.
  Stepan Shumyak, Li-Jun Yang, Shuhong Han, Haoyang Zhuang, Westley H. Reeves> ;Clinical Immunology. 2016 Nov 1
• 55 citations
  Irisin Inhibits Atherosclerosis by Promoting Endothelial Proliferation Through microRNA126-5p.
  Yuzhu Zhang, Haibo Song, Yuan Zhang, Fei Wu, Qian Mu, Miao Jiang, Fang Wang, Wen Zhang, Liang Li, Lei Shao, Shiwu Li, Li-Jun Yang, Mingxiang Zhang, Qi Wu, Dongqi Tang> ;Journal of the American Heart Association. 2016 Sep 1
• 114 citations
  Irisin exerts dual effects on browning and adipogenesis of human white adipocytes.
  Yuan Zhang, Chao Xie, Hai Wang, Robin M. Foss, Morgan Clare, Eva Vertes George, Shiwu Li, Adam J. Katz, Henrique Cheng, Yousong Ding, Dongqi Tang, Westley H. Reeves, L...> ;American Journal of Physiology. Endocrinology and Metabolism. 2016 Aug 1
• 5 citations
  Cell-Permeable Peptide Blocks TLR4 Signaling and Improves Islet Allograft Survival.
  Huansheng Dong, Yong Zhang, Lili Song, Do-Sung Kim, Hongju Wu, Lijun Yang, Shiwu Li, Katherine A. Morgan, David B. Adams, Hongjun Wang> ;Cell Transplantation. 2016 Jul 1
• 80 citations
  Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction.
  Yuzhu Zhang, Qian Mu, Zheng Zhou, Haibo Song, Yuan Zhang, Fei Wu, Miao Jiang, Fang Wang, Wen Zhang, Liang Li, Lei Shao, Xingli Wang, Shiwu Li, Li-Jun Yang, Qi Wu, Ming...> ;Plos One. 2016 Jun 29
• 32 citations
  Angiopoietin-like protein 8 (betatrophin) is a stress-response protein that down-regulates expression of adipocyte triglyceride lipase.
  Yuan Zhang, Shiwu Li, William Donelan, Chao Xie, Hai Wang, Qi Wu, Daniel L. Purich, Westley H. Reeves, Dongqi Tang, Li-Jun Yang> ;Biochimica Et Biophysica Acta. 2016 Feb 1
• 16 citations
  Maintenance of autoantibody production in pristane-induced murine lupus
  Shuhong Han, Haoyang Zhuang, Yuan Xu, Pui Lee, Yi Li, Joseph C. Wilson, Osvaldo Vidal, Hong Seok Choi, Yu Sun, Li-Jun Yang, Westley H. Reeves> ;Arthritis Research & Therapy. 2015 Dec 30
• 2 citations
  Csf2 and Ptgs2 Epigenetic Dysregulation in Diabetes-prone Bicongenic B6.NODC11bxC1tb Mice.
  Erin Garrigan, Nicole S. Belkin, Federica Seydel, Zhao Han, Jamal Carter, Marcia McDuffie, Laurence Morel, Ammon B. Peck, Michael J. Clare-Salzler, Mark A. Atkinson, C...> ;Genetics & Epigenetics. 2015 Oct 11
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Journal Articles

• Transient receptor potential melastatin 4 channel is required for rat dental pulp stem cell proliferation and survival  
  Ngoc Tran TD, Stovall KE, Suantawee T, Hu Y, Yao S, Yang LJ, Adisakwattana S, Cheng H, Cell Prolif, 1/1/2017
• Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction  
  Zhang Y, Mu Q, Zhou Z, Song H, Zhang Y, Wu F, Jiang M, Wang F, Zhang W, Li L, Shao L, Wang X, Li S, Yang LJ, Wu Q, Zhang M, Tang D, PLoS One, 1/29/2016
• Cell-permeable Peptide Blocks TLR4 signaling and Improves Islet Allograft Survival  
  Dong H, Zhang Y, Song L, Kim D, Wu H, Yang LJ, Li S, Morgan KA, Adams, DB, Wang H, Cell Transplantation, 1/13/2016
• Angiopoietin-like protein 8 (betatrophin) is a stress-response protein that down-regulates expression of adipocyte triglyceride lipase  
  Zhang Y, Li S, Donelan W, Xie C, Wang H, Wu Q, Purich DL, Reeves WH, Tang D, Yang LJ, Biochimica Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1/1/2016
• Irisin Controls Growth, Intracellular Ca2+ Signals, and Mitochondrial Thermogenesis in Cardiomyoblasts  
  Xie C, Zhang Y, Tran TD, Wang H, Li S, George EV, Zhuang H, Zhang P, Kandel A, Lai Y, Tang D, Reeves WH, Cheng H, Ding Y, Yang LJ, PLoS One, 1/25/2015
• Pancreatic and Duodenal Homeobox Gene 1 (Pdx1) Suppresses hepatic transcription factor 1 alpha (HNF1alpha) Expression during Reprogramming of Human Hepatic Cells into ...  
  Donelan W, Li SW, Wang H, Lu S, Xie C, Tang DQ, Chang LJ, and Yang LJ, American J Translational Research, 1/15/2015
• Csf2 and Ptgs2 Epigenetic Dysregulation in Diabetes-prone Bicongenic B6NODC11bxC1tb Mice  
  Garrigan E, Belkin NS, Seydel F, Han Z, Carter J, McDuffie M, Morel L, Peck AB, Clare-Salzler MJ, Atkinson M, Wasserfall C, Davoodi-Semiromi A, Shi JD, Haskell-Luevano..., Genetic Epigenetics, 1/11/2015
• Irisin Induces Angiogenesis in Human Umbilical Vein Endothelial Cells In Vitro and in Zebrafish Embryos In Vivo via Activation of the ERK Signaling Pathway  
  Wu F, Song H, Zhang Y, Zhang Y, Mu Q, Jiang M, Wang F, Zhang W, Li L, Li H, Wang Y, Zhang M, Li S, Yang LJ, Meng Y, Tang D, PLoS One, 1/4/2015
• Maintenance of autoantibody production in pristane-induced murine lupus  
  Han S, Zhuang H, Xu Y, Lee P, Li Y, Wilson JC, Vidal O, Choi HS, Sun Y, Yang LJ, and Reeves WH, Arthritis Research Therapy, 1/1/2015
• Mechanisms of autoantibody production in systemic lupus erythematosus  
  Han S, Zhuang H, Shumyak S, Yang LJ, Reeves WH, Frontiers Immunology, 1/1/2015
• Animal models of interferon signature positive lupus  
  Zhuang H, Szeto C, Han S, Yang LJ, and Reeves WH, Frontiers Immunology, 1/1/2015
• Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis  
  Cho J, Seo J, Lim CH, Yang LJ, Shiratsuchi T, Lee MH, Chowdhury RR, Kasahara H, Kim JS, Oh SP, Lee YJ, Terada N, Cell Death Differentiation, 1/1/2015
• Irisin Promotes Human Umbilical Vein Endothelial Cell Proliferation through the ERK Signaling Pathway and Partly Suppresses High Glucose-Induced Apoptosis  
  Song H, Wu F, Zhang Y, Zhang YZ, Wang F, Jiang M, Wang Z, Zhang MX, Li SW, Yang LJ, Wang XL, Cui T, Tang D, PLoS One, 1/22/2014
• Histamine-induced Ca2+ signaling is mediated by TRPM4 channels in human adipose-derived stem cells  
  Tran TD, Zolochevska O, Figueiredo ML, Wang H, Yang LJ, Gimble JM, Yao S, Cheng H, Biochemistry Journal, 1/1/2014
• High level expression, efficient purification, and bioactivity of recombinant human metallothionein 3 (rhMT3) from methylotrophic yeast Pichia pastoris  
  Wu Q, Li B, Wu F, Yang LJ, Li SW, Li H, Wu D, Cui T, Tang D, Protein Expression & Purification, 1/1/2014
• Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling  
  Zhang Y, Li R, Meng Y, Li S, Donelan W, Zhao Y, Qi L, Zhang M, Wang X, Cui T, Yang LJ, Tang D, Diabetes, 1/1/2014
• TLR7/TNFalpha-mediated bone marrow damage in systemic lupus erythematosus  
  Zhuang H, Han S, Xu Y, Wang H, Li Y, Yang LJ, and Reeves WH, Arthritis & Rheumatism, 1/1/2014
• Genetically reprogrammed, liver-derived insulin-producing cells are glucose-responsive, but susceptible to autoimmune destruction in settings of type 1 diabetes  
  Tang DQ, Lu S, Koya V, Qian K, Sun Y, Wang Q, Wang H, Li SW, Zhang C, Hansen B, Atkinson M, Phillips IM, and Yang LJ, American Journal of Translational Research, 1/28/2013
• The Novel Autoantigens in Type 1 Diabetes  
  Han S, Donelan W, Wang H, Reeves W, and Yang LJ, American Journal of Translational Research, 1/24/2013
• Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells  
  Weinstein JS, Delano MJ, Kelly-Scumpia KM, DC Nacionales DC, Li Y, Lee PY, Scumpia PO, Yang LJ, Sobel E, Moldawer LL, and Reeves WH, The Journal of Immunology, 1/15/2013
• Reprogrammed intermediate state of hepatic cells is more susceptible to pancreatic beta cell differentiation  
  Wang Q, Wang H, Li SW, Yu Sun, Wang X, Donelan W, Chang LJ, Jin S, Terada N, Reeves WH, and Yang LJ, Journal of Cell Science, 1/1/2013
• miR-375 regulation of CIP2A controls oral cancer cell proliferation and survival  
  Jung HM, Wang H, Rushi S, Patel, BL. Phillips WC, Reinhold DM, Chang LJ, Yang LJ, and Chan E, Molecular Biology of the Cell, 1/1/2013
• Breast implant-associated ALK-negative anaplastic large cell lymphoma: Case report and discussion of possible pathogenesis  
  George Vertes E, Pharm J, Houston C, Brian G, Al-Quran S, Dong H, Wang H, Reeves WH and Yang LJ, International Journal of Clinical Experimental Pathology, 1/1/2013
• High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pi...  
  Li H, Hui X, Yang S, Hu X, Tang X, Li P, Li S, Yang L, Jin S, Wang Y, Xu A, Wu D, Protein Expression & Purification, 1/1/2013
• Novel detection of pancreatic and duodenal homeobox 1 autoantibodies (PAA) in human sera using luciferase immunoprecipitation systems (LIPS) assay  
  Donelan W, Wang H, Li SW, Pittman D, Li Y, Han S, Sun Y, Carter C, Atkinson MA, Reeves WH, Winter WE, and Yang LJ, Int J Clin Exp Pathol, 1/1/2013
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Books/Book Chapters

• "Systemic Lupus Erythematosus (SLE)" 
  Chapter: "Origins of antinuclear antibodies." 
  Page 213 - 233Reeves WH, Y Xu, H Zhuang, Y Li, and Yang LJEditors: RG Lahita, G Tsokos, J Buyon, and T Koike.Academic Press, LondonEdition 5th,2011
• "Type 1 Diabetes / Book 1" 
  Chapter: "Autoantigen-Specific Immunotherapy" 
  Page 425 - 452Suhong Han, William Donelan, Westley Reeves, and Li-Jun YangInTech2011
• Introduction to Clinical Immunology 
  Chapter: Autoimmunity 
  Page 91 - 118Zhuang H, M Kosboth, J Sipos, M Satoh, Yang LJ, and WH ReevesEditors: J Zabriskie.Cambridge University Press2009
• Progress in Stem Cell Research 
  Chapter: The many faces of adult stem cell-derived, in vitro-generated insulin-producing islet-like cells for the treatment of type 1 diabetes. 
  Peck AB, Petersen B, Ramiya V and Yang LJEditors: Markino M.Nova Science Publishers, Inc., NY2006
• Regulation of Hepatic Function 
  Chapter: Mechanism of receptor-mediated Ca2+ entry into rat hepatocytes. 
  Page 276 - 289Williamson, JR and Yang LJMunksgard Int. Publ.1991
• Biological Signal Transduction 
  Chapter: Epidermal growth factor mediated signal transduction in rat hepatocytes. 
  Page 511 - 525Yang LJ, Baffy G., Rhee SG and Williamson JREditors: K.Wirtz.Springer Verlag, New York1991
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Lectures

• "Irisin, burning fat to fight obesity." 
  1/21/2016
• "Pdx1 and protein therapy in treating diabetes." 
  Haikou, Hainan, China - 1/11/2013
• "Diabetes and Cancer: Is there a connection?" 
  Hunan Providence, China - 1/12/2012
• "Directed reprogramming hepatic stem cells into pancreatic beta cells." 
  Beijing, China - 1/11/2011
• "Stem cells and cell therapy for diabetes." 
  Tianjin, China - 1/3/2011
• "Role of Pdx1 in regenerative medicine for treatment of diabetes." 
  Winston-Salem, NC - 1/23/2010
• "Role of Pdx1 in pancreatic beta cell regeneration." 
  1/19/2010
• "Generation of Induced Pluripotent Stem Cells Using Lentiviral Vectors Encoding Reprogramming Factors plus Cell Growth and Survival Regulatory Genes as well as Several... 
  Salerno, Italy - 1/17/2010
• "Pdx1- A novel pancreatic beta cell-specific autoantigen." 
  1/16/2010
• "Liver cell reprogramming with protein transduction." 
  Tel Aviv, Israel - 1/5/2010
• "Roles of Pdx1 protein in treatment of type 1 diabetes." 
  Cairo, Egypt - 1/5/2010
• "Reprogramming bone marrow stem cells into insulin-producing cells for cell replacement therapy." 
  Cairo, Egypt - 1/4/2010
• "Cell fate and reprogramming with protein transduction technology" 
  Wudang, China - 1/30/2009
• "Reprogramming hepatocytes into beta cells." 
  1/15/2009
• "Penetrating Protein Therapy for treatment of Diabetes" 
  Gainesville, FL - 1/3/2008
• "Generation of Beta-Cell Surrogates for a Cure of Diabetes" 
  Cleveland, OH - 1/17/2006
• "Stem cell and gene therapy of Type I diabetes." 
  Gainesville, FL - 1/29/2005
• "Beta-cell surrogates and type 1 diabetes." 
  Tampa, FL - 1/28/2005
• "Liver cell transdifferentiation into insulin-producing cells by genetic modification." 
  1/13/2005
• "Liver to Endocrine Pancreas Transdifferentiation" 
  San Diego, CA - 1/9/2005
• "Transdifferentiation of bone marrow-derived stem cells into functional insulin-producing cells." 
  Somerville, NJ - 1/23/2004
• "From bone marrow to functional insulin-producing cells." 
  Baltimore, MD - 1/22/2004
• "Generating beta-cell surrogates for treatment of type 1 diabetes." 
  Philadelphia, PA - 1/22/2004
• "Toward generating Beta-Cell surrogate from adult stem cells" 
  1/20/2004
• "Dendritic cell and T-cell therapy targeting multiple myeloma." 
  1/19/2004
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