Loren Anthony Laine MD

Gastroenterology•West Haven, CT

Physician

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950 Campbell AveWest Haven, CT 06516
Phone+1 203-937-3462

Education & Training

University of California (San Diego) Medical CenterFellowship, Gastroenterology, 1982 - 1985
UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Internal Medicine, 1979 - 1982
David Geffen School of Medicine at UCLAClass of 1979

Certifications & Licensure

CT State Medical License 2013 - 2025
CA State Medical License 1980 - 2021
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Gastroenterology

Awards, Honors, & Recognition

Fellow (AGAF) American Gastroenterological Association, 2009
Super Doctor SuperDoctors.com

Clinical Trials

A Randomized Comparative Pharmacokinetic Study of Oral Ganciclovir After Treatment With Intravenous Ganciclovir for Cytomegalovirus Gastrointestinal Disease in AIDS Patients
Completed
Phase 1
Trial of Oral Versus Intravenous Proton Pump Inhibitor on Intragastric pH in Patients With Bleeding Ulcers Start of enrollment: 2006 Feb 01
Completed
Not Applicable
Trial of Wireless Capsule Endoscopy in the Evaluation of Obscure Gastrointestinal Bleeding Start of enrollment: 2003 Mar 01
Completed
Phase 4
Early Colonoscopy for Lower Gastrointestinal (GI) Bleeding Start of enrollment: 2002 Aug 01
Terminated
Not Applicable
A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors Start of enrollment: 2012 Aug 13
Completed
Phase 3
Time Interval for Endoscopic Variceal Ligation Start of enrollment: 2008 Aug 01
Completed
Phase 4
Randomized Trial of Diphenhydramine Versus Continued Midazolam in "Difficult-to-sedate" Patients Undergoing Colonoscopy Start of enrollment: 2013 Feb 01
Completed
Not Applicable
Randomized Trial of Outpatient vs. Inpatient Management of Low-risk Patients With Upper Gastrointestinal Bleeding. Start of enrollment: 2013 Dec 01
Terminated
Not Applicable
Image-Enhanced Endoscopy (IEE) for Diagnosis of Non-Erosive Reflux Disease Start of enrollment: 2015 Mar 01
Completed
Evaluation of the National Randomized Proton Pump Inhibitor De-prescribing (RaPPID) Program Start of enrollment: 2019 Sep 16
COMPLETED
NA
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Publications & Presentations

PubMed

Canadian Association of Gastroenterology Clinical Practice Guideline for the Endoscopic Management of Nonvariceal Nonpeptic Ulcer Upper Gastrointestinal Bleeding.
Alan N Barkun, Loren Laine, Grigorios I Leontiadis, Ian M Gralnek, Nicholas Carman
Gastroenterology. 2025-08-08
1 citations
Expert of Experts Verification and Alignment (EVAL) Framework for Large Language Models Safety in Gastroenterology.
Mauro Giuffrè, Kisung You, Ziteng Pang, Simone Kresevic, Sunny Chung
NPJ Digital Medicine. 2025-05-03
Reply.
Amit Patel, Loren Laine, Paul Moayyedi
Gastroenterology. 2025-04-01

Journal Articles

Outcomes with Bloody vs. Coffee-Grounds Hematemesis
Loren Laine, MD, Nature
Analyses of Bloody vs. Coffee-Grounds Hematemesis
Loren Laine, MD, Nature

Press Mentions

Listen to "Yale Researchers Use Large Language Models to Detect Gastrointestinal Bleeding"February 28th, 2025
Vonoprazan Offers PPI Alternative for Heartburn with Non-Erosive RefluxOctober 10th, 2024
Listen to, "The First EHR-Based Machine Learning Model for GI Bleeding"September 9th, 2024
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Grant Support

Fecal Microbiota Transplant National RegistryAMERICAN GASTROENTEROLOGICAL ASSN/INST2016–2027

Professional Memberships

American Gastroenterological Association - AGA
Fellow