MackTRuffinIVMDMPH
Family Medicine • Hershey, PAProfessor, Chair Department of Family and Community Medicine
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Office
500 University Drive
Mail Code H154
Hershey, PA 17033Phone+1 717-531-8297Fax+1 717-531-5024- Is this information wrong?
Summary
- Dr. Ruffin began academic career in Department of Family Medicine at the University of Michigan Medical School. He was the Associate Chair for Research for 12 years leading the department to the top 10 in research funding. He was the inaugural holder of the Dr. Max and Buena Lichter Research Professorship in Family Medicine. He was voted into the Michigan Research League of Excellence in 2014.
The main focus of Dr. Ruffin’s research is cancer prevention and early detection. He began his research funding with a KO7 Career Development Award from NCI focused on practice transformation in the 1990’s. He has had a series of RO1’s focused on colorectal cancer prevention. His research team demonstrated that a single daily dose of aspirin could have long term biological changes in the colon tissue that explained the observational data of aspiring protecting one from colorectal cancer. He was a member of NCI Early Detection Research Network for colorectal cancer. This has led to an ongoing large validation study of new early detection biomarkers for colorectal cancer in serum, urine, and stool. His current research is focused in stool microbiome as a new early detection biomarker for colorectal cancer. He partnered with the Center for Disease Control and Prevention to refine and test an automated system to collect and process family health history. With support from the State of Michigan, he developed an interactive shared decision tool to help patients determined their preferred method of getting checked for colorectal cancer.
In September 2016, Dr. Ruffin joined Penn State Milton S. Hershey Medical Center, Penn State College of Medicine as Chair and Professor of Family & Community Medicine. He is the holder of the The Hershey Company Professor and Dr. and Mrs. Forney George Fellowship. He now leads over 100 faculty in 15 clinical sites, two residency programs, and two fellowships. He is actively recruiting research and clinical faculty.
Education & Training
University of Minnesota/University of Minnesota Medical CenterResidency, Family Medicine, 1987 - 1989
University of MinnesotaMPH, Epidemiology, 1987 - 1989
Wake Forest University School of MedicineResidency, Family Medicine, 1984 - 1987
Virginia Commonwealth University School of MedicineClass of 1984
Duke UniversityBSE, Biomedical Engineering, Magna Cum Laude, 1978 - 1980
Certifications & Licensure
PA State Medical License 2016 - 2024
MI State Medical License 1989 - 2024
NC State Medical License 1985 - 1990
MN State Medical License 1987 - 1989- American Board of Family Medicine Family Medicine
Awards, Honors, & Recognition
- The Hershey Company Professor Milton S. Hershey Medical Center, 2016-2018
- Dr. and Mrs. Forney George Fellowship Milton S. Hershey Medical Center, 2016-2018
- Curtis Hames Research Award The Society of TEeachers of Family Medicine, 2017
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Clinical Trials
- UMCC 9609 Tretinoin in Preventing Cancer of the Cervix in Patients With Cervical Neoplasia Start of enrollment: 1999 Jan 01
- Community Awareness, Resources and Education (CARE II): Project 3 Start of enrollment: 2011 Feb 01
Publications & Presentations
PubMed
- Exploratory Analysis of Concordance Between Clinician-Collected and Self-Sampled Human Papillomavirus Tests in a Small Cohort of Average- and High-Risk Patients.Ashley Wong, Juliette Entenman, Jennifer L Moss, Rebecca Morgis, Sarah I Ramirez, Amy L Hays, Tonya S Wright, Christina M Scartozzi, Mack T Ruffin> ;Women's Health Reports. 2024 Jan 1
- Increasing the adoption of evidence-based communication practices for HPV vaccination in primary care clinics: The HPV ECHO study protocol for a cluster randomized con...William A Calo, Parth D Shah, Benjamin N Fogel, Mack T Ruffin Iv, Jennifer L Moss, Bernice L Hausman, Joel E Segel, Erica Francis, Eric Schaefer, Chelsea M Bufalini, N...> ;Contemporary Clinical Trials. 2023 Aug 1
- 5 citationsSupport for HPV vaccine school-entry requirements in the United States: The role of exemption policies.William A Calo, Robert P Lennon, Mack T Ruffin Iv, Chelsea Keller, Katherine Spanos, Gail D'Souza, Jennifer L Kraschnewski> ;Vaccine. 2022 Dec 5
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Journal Articles
- The human gut microbiome as a screening tool for colorectal cancerZackular JP, Rogers MA, Ruffin MT 4th, Schloss PD, Cancer Prev Res (Phila), 8/7/2014
- Screening and prevention in primary careRuffin MT 4th, Shultz CG, Prim Care, 6/1/2014
- Pilot clinical study of the effects of ginger root extract on eicosanoids in colonic mucosa of subjects at increased risk for colorectal cancerZick SM, Turgeon DK, Ren J, Ruffin MT, Wright BD, Sen A, Djuric Z, Brenner DE, Mol Carcinog, 4/24/2014
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Abstracts/Posters
- Decisions to share results and seek further information following online personal genetic testingWang C, Dalia A, Roberts JS, Kalia S, Chen C, Ruffin M, Lehmann L, Mountain J, Moreno T, Green RC, Ann Behav Med, 1/1/2014
- Screening for Lung CancerRuffin MT, Department of Family Medicine Updates in Family Medicine Conference (CME course), Ann Arbor, MI, 10/3/2013
- Integrating Lung Cancer Screening Into Your PracticeRuffin MT, Department of Family Medicine Updates in Family Medicine Conference (CME course), Ann Arbor, MI, 10/3/2013
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Lectures
- HPV and cancerColumbus, OH - 4/3/2014
- Ginger supplementation and the expression of NF-kB in the normal-appearing colorectal mucosa of patients at high risk of colorectal cancer: results from a pilot random...Hilo, HI - 12/12/2011
- Human Papillomavirus (HPV) vaccine acceptance in Ohio AppalachiaSan Diego, CA - 10/28/2008
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Press Mentions
Legislation May Help Identify Breast Cancer Earlier in Certain at-Risk WomenSeptember 8th, 2021
Tips to Help Parents Share Family Health History with ChildrenNovember 13th, 2019
Take the Time to Ask About Your Family’s Health HistoryNovember 21st, 2018- Join now to see all
Grant Support
- P2 - Markers Of Pancreatic Cancer Using A Glycoproteomic ApproachNational Cancer Institute2010–2011
- HPV Immunization Response And StressNational Cancer Institute2010–2011
- Cancer Chemoprevention And Mentoring Clinical ResearchersNational Cancer Institute2006–2010
- HPV Infection And High Fruit And Vegetable Diet: Pilot ProjectNational Center For Research Resources2004–2006
- Human Papillomavirus In Men "Him": Pilot StudyNational Center For Research Resources2005
- Cancer Chemoprevention &Mentoring Clinical ResearchersNational Cancer Institute1999–2003
- All-Trans-Retinoic Acid (ATRA) In Women With Cervical Intraepithelial NeoplasiaNational Center For Research Resources1997–2002
- Retiniods And Intermediate Biomarkers For CIN I And IINational Cancer Institute1995–1999
- Preventive Oncology Academic AwardNational Cancer Institute1994–1996
- Preventive Oncology Acacemic AwardNational Cancer Institute1992–1994
Professional Memberships
- Society of Teachers of Family MedicineMember
- American Society of Preventive OncologyMember
- North American Primary Care Research GroupMember
Hospital Affiliations
Penn State Milton S. Hershey Medical CenterHershey, Pennsylvania
External Links
- Home pagehttps://research.med.psu.edu/departments/family-and-community-medicine/
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