MaimonHubbiMD

PubMed

• An Unusual Case of Isolated Gastric Cap Polyposis.
  Hansol Kang, Cooper Schwartz, Emma E Furth, Maimon E Hubbi> ;The American Journal of Gastroenterology. 2023 Nov 10
• A Rare Cause of Chronic Diarrhea and Peripheral Neuropathy.
  Hansol Kang, Maimon E Hubbi> ;Gastroenterology. 2024 Jan 1
• Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.
  Hubbi ME, Gilkes DM, Hu H, Kshitiz, Ahmed I, Semenza GL> ;Proceedings of the National Academy of Sciences of the United States of America. 2014-07-28
• 63 citations
  A calcineurin–Hoxb13 axis regulates growth mode of mammalian cardiomyocytes
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Nature. 2020 Apr 22
• Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation.
  Hubbi ME, Hu H, Kshitiz, Ahmed I, Levchenko A, Semenza GL> ;The Journal of biological chemistry. 2013-03-01
• MCM proteins are negative regulators of hypoxia-inducible factor 1.
  Hubbi ME, Luo W, Baek JH, Semenza GL> ;Molecular cell.
• 7 citations
  Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins.
  , , , , , , , , , , , , , , , > ;Integrative Biology. 2015 Mar 9
• An essential role for chaperone-mediated autophagy in cell cycle progression.
  Hubbi ME, Semenza GL> ;Autophagy.
• Isolated Erythrocytosis Associated With 3 Novel Missense Mutations in the EGLN1 Gene.
  Moore JA, Hubbi ME, Wang C, Wang Y, Luo W, Hofmann S, Rambally S> ;Journal of investigative medicine high impact case reports.
• 2 citations
  Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.
  Sela, Y., Li, J., Maheswaran, S., Norgard, R., Yuan, S., Hubbi, M., Doepner, M., Xu, J., Ho, E., Mesaros, C., Sheehan, C., Croley, G., Muir, A., Blair, I., Shalem, O.,...> ;Cancer Research. 2022 May 16
• 9 citations
  Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1α activity promoting proliferation of hypoxic cells.
  Kshitiz, Junaid Afzal, Yasir Suhail, Maimon E Hubbi, Archer Hamidzadeh, Ruchi Goyal, Yamin Liu, Peng Sun, Stefania Nicoli, Chi V Dang, Andre Levchenko, Chang, H.> ;Cell Systems. 2022 Dec 21
• Regulation of cell proliferation by hypoxia-inducible factors.
  Hubbi ME, Semenza GL> ;American journal of physiology. Cell physiology. 2015-10-21
• 28 citations
  Huntington’s disease: Neural dysfunction linked to inositol polyphosphate multikinase
  Ishrat Ahmed, Juan I. Sbodio, Maged M. Harraz, Richa Tyagi, Jonathan C. Grima, Maimon E. Hubbi, Risheng Xu, Seyun Kim, Bindu D. Paul, Solomon H. Snyder> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Aug 4
• 148 citations
  Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells
  Daniele M. Gilkes, Lisha Xiang, Sun Joo Lee, Maimon E. Hubbi, Denis Wirtz, Gregg L. Semenza> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Jan 21
• Sirtuin-7 inhibits the activity of hypoxia-inducible factors.
  Hubbi ME, Hu H, Kshitiz, Gilkes DM, Semenza GL> ;The Journal of biological chemistry. 2013-06-09
• 209 citations
  Collagen Prolyl Hydroxylases are Essential for Breast Cancer Metastasis
  Daniele M. Gilkes, Pallavi Chaturvedi, Saumendra Bajpai, Carmen Chak-Lui Wong, Hong Wei, Maimon E. Hubbi, Denis Wirtz, Gregg L. Semenza> ;Cancer Research. 2013 Jun 1
• A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication.
  Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL> ;Science signaling. 2013-02-12
• 187 citations
  Procollagen Lysyl Hydroxylase 2 Is Essential for Hypoxia-Induced Breast Cancer Metastasis
  Daniele M. Gilkes, Saumendra Bajpai, Carmen Chak-Lui Wong, Maimon E. Hubbi, Denis Wirtz, Gregg L. Semenza> ;Molecular Cancer Research. 2013 May 1
• 51 citations
  Matrix Rigidity Controls Endothelial Differentiation and Morphogenesis of Cardiac Precursors
  Maimon E. Hubbi, Eun Hyun Ahn, John E. Downey, Junaid Afzal, Deok Ho Kim, Sergio Rey, Connie Y. Chang, Arnab Kundu, Gregg L. Semenza, Roselle Abraham, Andre Levchenko> ;Science Signaling. 2012 Jun 5
• 171 citations
  Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.
  Carmen Chak-Lui Wong, Huafeng Zhang, Daniele M. Gilkes, Jasper Chen, Hong Wei, Maimon E. Hubbi, Gregg L. Semenza> ;Journal of Molecular Medicine. 2012 Jan 10
• Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.
  Hubbi ME, Gilkes DM, Baek JH, Semenza GL> ;The Journal of biological chemistry. 2012-01-04
• 119 citations
  Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
  Maimon E. Hubbi, Fan Pan, Karin R. McDonald, Malini Mansharamani, Robert N. Cole, Jun O. Liu, Gregg L. Semenza> ;The Journal of Biological Chemistry. 2007 Dec 21
• 52 citations
  Spermidine/Spermine-N1-Acetyltransferase 2 Is an Essential Component of the Ubiquitin Ligase Complex That Regulates Hypoxia-inducible Factor 1α
  Jin Hyen Baek, Ye V. Liu, Karin R. McDonald, Maimon E. Hubbi, Hweejo Byun, Gregg L. Semenza> ;The Journal of Biological Chemistry. 2007 Aug 10
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