Marc A Pfeffer MD

Adult Congenital Heart Disease, Heart Failure & Transplantation

Victor J. Dzau Professor of Medicine, Brigham and Women's Hospital

75 Francis StreetBrigham & Women's HospBoston, MA 02115
Phone+1 617-732-5681

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Education & Training

Mass General Brigham/Brigham and Women's HospitalFellowship, Cardiovascular Disease, 1979 - 1980
Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 1976 - 1979
University of Oklahoma College of MedicineClass of 1976

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Certifications & Licensure

MA State Medical License 1980 - 2027
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 2 Certification Outgoing Public Health Reporting from EpicCare Functionality, Epic Systems Corporation, 2012, 2014-2017
CMS Meaningful Use Stage 2 Certification EpicCare Inpatient 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014-2017
CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2012, 2014-2017

Clinical Trials

ARISE - Aggressive Reduction of Inflammation Stops Events
UNKNOWN
PHASE3

Publications & Presentations

PubMed

Optimal serum potassium concentrations in heart failure: an individual patient data meta-analysis.
Ryohei Ono, Misato Chimura, Kieran F Docherty, Alasdair D Henderson, Ross Campbell
European Heart Journal. 2026-08-24
MRAs and Race in Heart Failure: An Individual Participant Data Meta-Analysis of Randomized Trials.
Jawad H Butt, Pardeep S Jhund, Alasdair D Henderson, Atefeh Talebi, Orly Vardeny
Circulation. Heart Failure. 2026-08-07
Using Days Alive and Out of Hospital as the Study Endpoint in Cardiovascular Heart Failure Clinical Trials.
Zachary R McCaw, Stephanie Armbruster, Lu Tian, Brian L Claggett, Garrett Fitzmaurice
JACC. Heart Failure. 2026-07-01

Journal Articles

Atrial Fibrillation in Heart Failure with Preserved Ejection Fraction
Amil M Shah, Nancy K Sweitzer, Akshay S Desai, James C Fang, Sanjeev Saksena, Bertram Pitt, Sanjiv J Shah, Marc A Pfeffer, Scott D Solomon, ScienceDirect

Lectures

Progression from Hypertension to Heart Failure: Mechanisms, Epidemiology, and Prevention
55th Annual Scientific Session & Expo, Atlanta, Georgia, USA
Progression from Hypertension to Heart Failure: Mechanisms, Epidemiology, and Prevention
American College of Cardiology, 55th Annual Scientific Session & Expo, Atlanta, Georgia, USA
TOPCAT: Effects of Spironolactone on CV Outcomes in Patients With Heart Failure With Preserved Ejection Fraction
American Heart Association, Scientific Sessions 2013, Dallas, Texas, USA

Other

Angiotensin II receptor blockers in heart failure due to systolic dysfunction: Therapeutic use
Pfeffer MA, Colucci WS
http://www.uptodate.com/contents/angiotensin-ii-receptor-blockers-in-heart-failure-due-to-systolic-d
UpToDate, Wolters Kluwer Health - 2012-06-29

Authored Content

Serum Phosphorus and Risk of Cardiovascular Disease, All-Cause Mortality, or Graft Failure in Kidney Transplant Recipients: An Ancillary Study of the FAVORIT Trial CohortJune 2017
Serum Phosphorus and Risk of Cardiovascular Disease, All-Cause Mortality, or Graft Failure in Kidney Transplant Recipients: An Ancillary Study of the FAVORIT Trial CohortJune 2017
Serum Phosphorus and Risk of Cardiovascular Disease, All-Cause Mortality, or Graft Failure in Kidney Transplant Recipients: An Ancillary Study of the FAVORIT Trial CohortJune 2017

Press Mentions

Experts Challenge Aspirin Guidelines Based on Their Undue Reliance on a Flawed TrialApril 2nd, 2025
PARADISE-MI: Sacubitril-Valsartan Fails to Outperform ACE Inhibitor After MINovember 11th, 2021
ACC.21: Late-Breaking Science Brings Practice-Changing InsightsJune 17th, 2021