MargaretMO'NeillMD

PubMed

• Mitigation of Off Target Adrenergic Inhibition and Effects on Cardiovascular Function in the Discovery Novel RSK2 Inhibitors.
  Fryer, R.M., Muthukumarana, A., Chen, R.R., Smith, J.D., Nodop Mazurek, S., Harrington, K.E., Dinallo, R.M., Burke, J., Dicapua, F.M., Guo, X., Kirrane, T.M., Snow, R....> ;J Pharmacol Exp Ther. 2012 Mar
• Indole RSK inhibitors. Part 2: Optimization of cell potency and kinase selectivity.
  Kirrane, T.M., Boyer, S.J., Burke, J., Guo, X., Snow, R.J., Soleymanzadeh, L., Swinamer, A., Zhang, Y., Madwed, J.B., Kashem, M., Kugler, S., O'Neill, M.M.> ;Bioorg Med Chem Lett. 2012 Jan 1
• Indole RSK inhibitors. Part 1: Discovery and initial SAR.
  Boyer, S.J., Burke, J., Guo, X., Kirrane, T.M., Snow, R.J., Zhang, Y., Sarko, C., Soleymanzadeh, L., Swinamer, A., Westbrook, J., Dicapua, F., Padyana, A., Cogan, D., ...> ;Bioorg Med Chem Lett. 2012 Jan 1
• Identification of pharmacological inhibitors of the MEK5/ERK5 pathway.
  Tatake, R.J., O'Neill, M.M., Kennedy, C.A., Wayne, A.L., Jakes, S., Wu, D., Kugler, S.Z., Kashem, M.A., Kaplita, P., Snow, R.J.> ;Biochem Biophys Res Commun. 2008-12-05
• Glucose-regulated insulin production from genetically engineered human non-beta cells.
  Tatake, R. J., O'Neill, M. M., Kennedy, C. A., Reale, V. D., Runyan, J. D., Monaco, K. A., Yu, K., Osborne, W. R., Barton, R. W., Schneiderman, R. D.> ;Life Sci. 2007 Oct 13
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