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Office
3636 Boulevard of the Allies
University of Pittsburgh Hemophilia Center of Western PA
Pittsburgh, PA 15213Phone+1 412-209-7288- Is this information wrong?
Education & Training
- University of Pittsburgh Graduate School of Public HealthMPH, Epidemiology, 1991 - 1993
- UPMC Medical EducationFellowship, Hematology and Medical Oncology, 1978 - 1982
- UPMC Medical EducationResidency, Internal Medicine, 1975 - 1978
- University of Pittsburgh School of MedicineClass of 1975
Certifications & Licensure
- PA State Medical License 1976 - 2024
Clinical Trials
- Phase II Study of IL-11 (Neumega) in Von Willebrand Disease Start of enrollment: 2004 Jul 01
- Rituximab to Treat Severe Hemophilia A Start of enrollment: 2006 Jun 01
- LTFU for Gene Transfer Subjects With Hemophilia B Start of enrollment: 2007 Aug 01
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Publications & Presentations
PubMed
- A Review of the Rationale for Gene Therapy for Hemophilia A With Inhibitors: One-Shot Tolerance and Treatment?Leonard A Valentino, Margareth C Ozelo, Roland W Herzog, Nigel S Key, Allyson M Pishko, Margaret V Ragni, Benjamin J Samelson-Jones, David Lillicrap> ;Journal of Thrombosis and Haemostasis. 2023 May 22
- 8 citationsBuilding the foundation for a community-generated national research blueprint for inherited bleeding disorders: facilitating research through infrastructure, workforce...Margaret V Ragni, Guy Young, Glaivy Batsuli, Emily Bisson, Shannon L Carpenter, Stacy E Croteau, Adam Cuker, Randall G Curtis, Michael Denne, Bruce Ewenstein, Amber Fe...> ;Expert Review of Hematology. 2023 Mar 1
- 1 citationsPost hoc longitudinal assessment of efficacy and safety of recombinant factor IX Fc fusion protein in hemophilia B.Amy D Shapiro, Roshni Daniel Kulkarni, Margaret V Ragni, Herve Chambost, Johnny N Mahlangu, Johannes Oldenburg, Beatrice Nolan, Margareth C Ozelo, Meredith C Foster, A...> ;Blood Advances. 2023 Feb 27
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Journal Articles
- BIVV001 Fusion Protein as Factor VIII Replacement Therapy for Hemophilia ADoris V Quon, Margaret V Ragni, The New England Journal of Medicine
Abstracts/Posters
- Innate Immune Mechanism of Hemarthrosis in Hemophilia-a MiceMargaret V. Ragni, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- Mechanism of Pulmonary Thrombosis in Hemolytic DisordersMargaret V. Ragni, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
- FVIII Protein Is Not Detectable in Human PBMCs or Livers from Dogs with an Intron-22 Inversion Mutation: Implications for FVIII Immunogenicity and ToleranceMargaret V. Ragni, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
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Lectures
- Hemostasis and Thrombosis61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
- Von Willebrand Disease Minimize Menorrhagia (VWDMin) Trial61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
- Coagulation Conundrum Roundtable: Case-based Discussion on the Implications of Exogenous Estrogens in Hemostasis and Thrombosis61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
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Authored Content
- Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX VariantDecember 2017
Press Mentions
- Coagulation Conundrums: Managing Hemostatic and Thrombotic Complications in Young WomenNovember 8th, 2019
- Gα13 Is Closely Related to Hematopoiesis in ZebrafishNovember 27th, 2010
- Gene Therapy Shows Promise in Hemophilia BDecember 5th, 2016
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Grant Support
- Training Students In Biomedical Research In HematologyNational Heart, Lung, And Blood Institute2005–2012
- Hemophilia Adult Prophylaxis StudyNational Heart, Lung, And Blood Institute2011
- Ph2 Comp Hemostatic Of Escal Doses Interleukin-11 W/Type 1 Von Willebrand DISNational Center For Research Resources2005
- Impact Of HIV On Hepatitis C In Hemophilia (3HS)National Center For Research Resources2004–2005
- Ph1 Sfy Sty PTS W/Severe Hemophilia B Using AavvNational Center For Research Resources2004
- Impact Of HIV On Hepatitis C Infection In HemophiliaNational Heart, Lung, And Blood Institute2001–2004
- Factor VIII Vector For Severe Hemophilia ANational Center For Research Resources2000–2002
- Epidemiology And Immunology Of Hemophilia A InhibitorsNational Heart, Lung, And Blood Institute1998–2001
- Safety/Efficacy Of Kogenate 2 Antihemophilic Factor Recombinant Free Of AlbuminNational Center For Research Resources1998–1999
- Safety And Efficacy Of Human Recombinant Factor (RHFIX) In Hemophilia B PatientsNational Center For Research Resources1998–1999
- Safety &Efficacy Of Kogenate-2 Antihemophilic Factor RecombinantNational Center For Research Resources1997
- Pharmacokinetic, Safety And Efficacy Study Of Human Recombinant Factor (RHFIX)National Center For Research Resources1997
- Three-Segment, Phase I/II Study Of RH Factor IX In Patients With Hemophilia BNational Center For Research Resources1996
- Study Of Hiv-Associated Malignancy In HemophiliacsNational Cancer Institute1989–1993
- Hiv-Associated Malignancy In HemophiliacsNational Cancer Institute1992
Hospital Affiliations
- UPMC PresbyterianPittsburgh, Pennsylvania
- UPMC Magee-Womens HospitalPittsburgh, Pennsylvania
- Shadyside CampusPittsburgh, Pennsylvania
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