MarkGAngelosMD

Emergency Medicine • Columbus, OH

Undersea & Hyperbaric Medicine, Critical Care Medicine

Professor and Chair Department of Emergency Medicine, Ohio State University College of Medicine

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Office
376 W 10th Ave
760 Prior Hall
Columbus, OH 43210
Phone+1 614-293-8305

Fax+1 614-293-6570
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Education & Training

UPMC Medical Education/Presbyterian Shadyside HospitalFellowship, Critical Care Medicine, 1985 - 1987
Wright State UniversityResidency, Emergency Medicine, 1982 - 1985
University of Utah School of MedicineClass of 1982

Certifications & Licensure

UT State Medical License 2021 - 2026
OH State Medical License 1983 - 2023
NY State Medical License 2015 - 2017
American Board of Emergency Medicine Emergency Medicine

Awards, Honors, & Recognition

Fellow (FACEP) American College of Emergency Physicians

Publications & Presentations

PubMed

16 citations
Scalable Biomimetic Coaxial Aligned Nanofiber Cardiac Patch: A Potential Model for "Clinical Trials in a Dish".
Naresh Kumar, Arunkumar Palaniappan, Julie A. Dougherty, Andras Czirok, Dona Greta Isai, Muhamad Mergaye, Mark G. Angelos, Heather M. Powell, Mahmood Khan, Divya Sridh...> ;Frontiers in Bioengineering and Biotechnology. 2020 Sep 16
2 citations
The Impact of Selecting Specific Cohorts for Benchmarking and Interpretation of Emergency Department Patient Satisfaction Scores
Gregory M. Archual, Ashish R. Panchal, Mark G. Angelos, David P. Way> ;Academic Emergency Medicine. 2020 May 1
19 citations
Human Cardiac Progenitor Cells Enhance Exosome Release and Promote Angiogenesis Under Physoxia.
Julie A. Dougherty, Nil Patel, Naresh Kumar, Shubha Gururaja Rao, Mark G. Angelos, Harpreet Singh, Chuanxi Cai, Mahmood Khan> ;Frontiers in Cell and Developmental Biology. 2020 Mar 6
23 citations
Assessment of temporal functional changes and miRNA profiling of human iPSC-derived cardiomyocytes.
Naresh Kumar, Julie A. Dougherty, Heather R. Manring, Ibrahim Elmadbouh, Muhamad Mergaye, Andras Czirok, Dona Greta Isai, Andriy E. Belevych, Lianbo Yu, Paul M.L. Jans...> ;Scientific Reports. 2019 Sep 12
19 citations
Sustained Release of Basic Fibroblast Growth Factor (bFGF) Encapsulated Polycaprolactone (PCL) Microspheres Promote Angiogenesis In Vivo.
P. Arunkumar, Julie A. Dougherty, Jessica Weist, Naresh Kumar, Mark G. Angelos, Heather M. Powell, Mahmood Khan> ;Nanomaterials. 2019 Jul 20
38 citations
Extracellular Vesicles Released by Human Induced-Pluripotent Stem Cell-Derived Cardiomyocytes Promote Angiogenesis.
Julie A. Dougherty, Naresh Kumar, Mohammad Noor, Mark G. Angelos, Mohsin Khan, Chun-An Chen, Mahmood Khan> ;Frontiers in Physiology. 2018 Dec 14
38 citations
Potential Role of Exosomes in Mending a Broken Heart: Nanoshuttles Propelling Future Clinical Therapeutics Forward.
Julie A. Dougherty, Muhamad Mergaye, Naresh Kumar, Chun-An Chen, Mark G. Angelos, Mahmood Khan> ;Stem Cells International. 2017 Oct 15
18 citations
Dual-Specificity Phosphatase 4 Overexpression in Cells Prevents Hypoxia/Reoxygenation-Induced Apoptosis via the Upregulation of eNOS
Julie A. Dougherty, Joanna Kilbane Myers, Mahmood Khan, Mark G. Angelos, Chun-An Chen> ;Frontiers in Cardiovascular Medicine. 2017 Apr 24
33 citations
Modulation of p38 kinase by DUSP4 is important in regulating cardiovascular function under oxidative stress.
Alma Barajas-Espinosa, Ariel Basye, Mark G. Angelos, Chun-An Chen> ;Free Radical Biology & Medicine. 2015 Dec 1
51 citations
MicroRNA-133a engineered mesenchymal stem cells augment cardiac function and cell survival in the infarct heart.
Duaa Dakhlallah, Jianying Zhang, Lianbo Yu, Clay B. Marsh, Mark G. Angelos, Mahmood Khan> ;Journal of Cardiovascular Pharmacology. 2015 Mar 1
19 citations
Evaluation of Changes in Morphology and Function of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (HiPSC-CMs) Cultured on an Aligned-Nanofiber Cardiac Patch.
Mahmood Khan, Yanyi Xu, Serena Hua, Jed Johnson, Andriy Belevych, Paul M L Janssen, Sandor Gyorke, Jianjun Guan, Mark G Angelos> ;Plos One. 2015 Jan 1
17 citations
Correction: Evaluation of Changes in Morphology and Function of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (HiPSC-CMs) Cultured on an Aligned-Nanofiber...
Mahmood Khan, Yanyi Xu, Serena Hua, Jed Johnson, Andriy Belevych, Paul M L Janssen, Sandor Gyorke, Jianjun Guan, Mark G Angelos> ;Plos One. 2015 Jan 1
46 citations
Comparison of human induced pluripotent stem-cell derived cardiomyocytes with human mesenchymal stem cells following acute myocardial infarction.
Lucas Citro, Shan Naidu, Fatemat Hassan, M. Lakshmi Kuppusamy, Periannan Kuppusamy, Mark G. Angelos, Mahmood Khan> ;Plos One. 2014 Dec 31
2 citations
Effect of pulmonary-generated reactive oxygen species on left-ventricular dysfunction associated with cardio-pulmonary ischemia-reperfusion injury.
Mahmood Khan, Mark E. Brauner, Michael C. Plewa, Vijay Kumar Kutala, Mark G. Angelos, Periannan Kuppusamy> ;Cell Biochemistry and Biophysics. 2013 Nov 1
91 citations
Emerging role of oxidative stress in metabolic syndrome and cardiovascular diseases: important role of Rac/NADPH oxidase
Mohammad T. Elnakish, Hamdy H. Hassanain, Paul M.L. Janssen, Mark G. Angelos, Mahmood Khan> ;The Journal of Pathology. 2013 Nov 1
10 citations
Sivelestat Attenuates Myocardial Reperfusion Injury during Brief Low Flow Postischemic Infusion
Sverre E. Aune, Steve T. Yeh, Periannan Kuppusamy, M. Lakshmi Kuppusamy, Mahmood Khan, Mark G. Angelos> ;Oxidative Medicine and Cellular Longevity. 2013 May 22
11 citations
Hyperoxemic reperfusion after prolonged cardiac arrest in a rat cardiopulmonary bypass resuscitation model
Steve T. Yeh, Sverre E. Aune, Traci A. Wilgus, Allison E. Parent, Mark G. Angelos> ;Resuscitation. 2013 Jan 1
30 citations
Post-cardiac arrest hyperoxia and mitochondrial function.
Mark G. Angelos, Steve T. Yeh, Sverre E. Aune> ;Resuscitation. 2011 Dec 1
5 citations
Measurement of hydrogen peroxide and oxidant stress in a recirculating whole blood-perfused rat heart model
Sverre E. Aune, Steve T. Yeh, Daniel P. Zelinski, Mark G. Angelos> ;Resuscitation. 2011 Feb 1
602 citations
Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality
J. Hope Kilgannon, Alan E. Jones, Nathan I. Shapiro, Mark G. Angelos, Barry Milcarek, Krystal Hunter, Joseph E. Parrillo, Stephen Trzeciak> ;JAMA. 2010 Jun 2
1 citations
Simplified method for concentration of mitochondrial membrane protein complexes.
Steve T. Yeh, Mark G. Angelos, Yeong Renn Chen> ;Electrophoresis. 2010 Jun 1
34 citations
Preservation of mitochondrial function with cardiopulmonary resuscitation in prolonged cardiac arrest in rats
Steve T. Yeh, Hsin-Ling Lee, Sverre E. Aune, Chwen-Lih Chen, Yeong Renn Chen, Mark G. Angelos> ;Journal of Molecular and Cellular Cardiology. 2009 Dec 1
51 citations
Oxygen requirement during cardiopulmonary resuscitation (CPR) to effect return of spontaneous circulation
Steve T. Yeh, Rebelcah J. Cawley, Sverre E. Aune, Mark G. Angelos> ;Resuscitation. 2009 Aug 1
1 citations
Postarrest nitric oxide effect depends on the source
Mark G. Angelos> ;Critical Care Medicine. 2009 Jan 1
59 citations
Cardiovascular response to epinephrine varies with increasing duration of cardiac arrest
Mark G. Angelos, Ryan Butke, Ashish R. Panchal, Carlos A. A. Torres, Alan Blumberg, James Schneider, Sverre E. Aune> ;Resuscitation. 2008 Apr 1
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Press Mentions

Wexner Medical Center Achieves Gold Standard for Geriatric Emergency CareSeptember 12th, 2018

Professional Memberships

American College of Emergency Physicians - ACEP
Fellow

Hospital Affiliations

The OSUCCC - JamesColumbus, Ohio