MarkTDransfieldMD

Pulmonology • Birmingham, AL

Critical Care Medicine

Professor, Medicine, University of Alabama School of Medicine

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Office
1900 University Blvd
422 THT
Birmingham, AL 35294
Phone+1 205-934-5425

Fax+1 205-975-5666
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Summary

Medical Director, UAB Lung Health Center

Education & Training

University of Alabama Medical CenterFellowship, Pulmonary Disease and Critical Care Medicine, 2000 - 2003
University of Alabama Medical CenterResidency, Internal Medicine, 1997 - 2000
University of North Carolina at Chapel Hill School of MedicineClass of 1997

Certifications & Licensure

AL State Medical License 1998 - 2024
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2012

Clinical Trials

US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study Start of enrollment: 2007 Feb 01
Completed
Phase 2
Biologic Lung Volume Reduction (BLVR) Phase 2 Homogeneous Study Start of enrollment: 2008 Feb 01
Completed
Phase 2
Long-term Oxygen Treatment Trial Start of enrollment: 2009 Jan 01
Completed
Phase 3
Pilot Study of Tetomilast in Chronic Obstructive Pulmonary Disease (COPD) Associated With Emphysema Start of enrollment: 2009 Mar 01
Terminated
Phase 2
Simvastatin Therapy for Moderate and Severe COPD Start of enrollment: 2010 Mar 01
Terminated
Phase 3
Effects of cKit Inhibition by Imatinib in Patients With Severe Refractory Asthma (KIA) Start of enrollment: 2010 Nov 01
Completed
Phase 2
Symbicort in Airway Predominant Chronic Obstructive Pulmonary Disease (COPD) Start of enrollment: 2012 Apr 01
Completed
Phase 4
Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study Start of enrollment: 2012 Oct 01
Terminated
Not Applicable
Pulmonx Endobronchial Valves Used in Treatment of Emphysema (LIBERATE Study) Start of enrollment: 2013 Jul 01
Completed
Not Applicable
Study of COPD Subgroups and Biomarkers Start of enrollment: 2010 Nov 01
Active, not recruiting
TOPIC Trial for COPD Start of enrollment: 2015 May 01
Completed
Early Phase 1
Evaluation of COPD Co-Pilot Start of enrollment: 2016 Oct 01
Unknown status
The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor Start of enrollment: 2017 Mar 16
Completed
Phase 2
Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency Start of enrollment: 2019 Apr 08
Completed
Phase 2
The Multicenter Topic Trial Start of enrollment: 2021 Dec 01
Withdrawn
Phase 2
COVID-19 Study of Safety and Tolerability of Alvelestat Start of enrollment: 2021 Jan 25
Completed
Phase 1, Phase 2
An Observational Study of Beta-Blocker Use in Patients With COPD and Acute MI Start of enrollment: 2020 Jun 28
Completed
SPIROMICS Study of Early COPD Progression (SOURCE) Start of enrollment: 2021 Sep 08
Recruiting
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Publications & Presentations

PubMed

The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort.
Rajat Suri, Daniela Markovic, Han Woo, Mehrdad Arjomandi, R Graham Barr, Russell P Bowler, Gerard Criner, Jeffrey L Curtis, Mark T Dransfield, M Bradley Drummond, Spyr...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Mar 20
Bronchiectasis-COPD Overlap: A ROSE by Any Other Name?
LaFon, D., Dransfield, M.> ;American Journal of Respiratory and Critical Care Medicine. 2024 Mar 7
Project EPIC (Empowering People to Independence in COPD): Study protocol for a hybrid effectiveness-implementation pilot randomized controlled trial of telephonic, ger...
Jun Y Byun, Rachel Wells, Avery C Bechthold, Jazmine Coffee-Dunning, Margaret Armstrong, Richard Taylor, Lanier O'Hare, Mark T Dransfield, Cynthia J Brown, David E Van...> ;Contemporary Clinical Trials. 2024 Mar 6
Low dose cadmium exposure regulates miR-381-ANO1 interaction in airway epithelial cells.
Singh, P., Li, F., Stephens, C., Zheng, H., Kumar, A., Dsouza, K., Dransfield, M., Antony, V.> ;Scientific Reports. 2024 Jan 2
Cognitive behavioural therapy sessions approach ineffective for anxiety and depression in COPD: is the door closed for good?
Yohannes, A., Hoth, K., Iyer, A., Dransfield, M.> ;The European Respiratory Journal. 2024 Jan 1
Bronchial rheoplasty for chronic bronchitis: 2-year results from a US feasibility study with RheOx.
Sciurba, F., Dransfield, M., Kim, V., Marchetti, N., Comellas, A., Hogarth, D., Majid, A.> ;BMJ Open Respiratory Research. 2023 Dec 26
Chronic obstructive pulmonary disease: hiding in plain sight, a Statement from the COPD Foundation Medical and Scientific Advisory Committee.
Surya P Bhatt, Richard Casaburi, Alvar Agusti, Bartolome R Celli, Bruce E Miller, Nirupama Putcha, Jean Rommes, Mark T Dransfield> ;The Lancet. Respiratory Medicine. 2023 Dec 1
Associations Between Coronary Artery Calcium Score and Exacerbation Risk in BLOCK-COPD.
Sharon X Ling, Erika S Helgeson, Helen Voelker, Wassim W Labaki, Daniel Meza, Oisin O'Corragain, Jennifer Y So, Gerard J Criner, MeiLan K Han, Ravi Kalhan, Robert M Re...> ;Chronic Obstructive Pulmonary Diseases. 2024 Jan 25
Association between P-pulmonale and respiratory morbidity in COPD: a secondary analysis of the BLOCK-COPD trial.
Takudzwa Mkorombindo, Sharon X Ling, Erika S Helgeson, David M MacDonald, Krystle Pew, Helen Voelker, Vera Bittner, Ken M Kunisaki, Mark T Dransfield, Wade, R. C., R C...> ;BMC Pulmonary Medicine. 2023 Nov 9
The Chronic Obstructive Pulmonary Disease (COPD)-Bronchiectasis Overlap Syndrome: Does My COPD Patient Have Bronchiectasis on Computed Tomography? "Frankly, My Dear, I...
Mark L Metersky, Mark T Dransfield> ;American Journal of Respiratory and Critical Care Medicine. 2023 Dec 15
1 citations
Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry.
William McKleroy, Tracie Shing, Wayne H Anderson, Mehrdad Arjomandi, Hira Anees Awan, Igor Barjaktarevic, R Graham Barr, Eugene R Bleecker, John Boscardin, Russell P B...> ;JAMA. 2023 Aug 1
3 citations
Changes in Lung Volumes with Spirometric Disease Progression in COPD.
Bhatt, S. P., Mehrdad Arjomandi, Siyang Zeng, Jianhong Chen, Surya P Bhatt, Fereidoun Abtin, Igor Barjaktarevic, R Graham Barr, Eugene R Bleecker, Russell G Buhr, Gera...> ;Chronic Obstructive Pulmonary Diseases. 2023 Jul 26
The Lancet COPD Commission: broader questions remain - Authors' reply.
Mark T Dransfield, Daiana Stolz> ;Lancet. 2023 May 13
Pushing (for) GOLD.
Mark Dransfield, Ravi Kalhan, Daiana Stolz> ;The European Respiratory Journal. 2023 Apr 1
1 citations
Using Community Health Advisors to Increase Lung Cancer Screening Awareness in the Black Belt: a Pilot Study.
Soumya J Niranjan, William Opoku-Agyeman, Claudia M Hardy, Tara Bowman, Agasthya Vedre-Kyanam, Kristine Ria Hearld, Mark T Dransfield, Monica L Baskin> ;Journal of Cancer Education. 2023 Aug 1
1 citations
Project EPIC (Early Palliative Care In COPD): A Formative and Summative Evaluation of the EPIC Telehealth Intervention.
Anand S Iyer, Rachel D Wells, J Nicholas Dionne-Odom, Avery C Bechthold, Margaret Armstrong, Jun Yeong Byun, Lanier O'Hare, Richard Taylor, Stephanie Ford, Jazmine Cof...> ;Journal of Pain and Symptom Management. 2023 Apr 1
3 citations
Increased chest CT derived bone and muscle measures capture markers of improved morbidity and mortality in COPD.
Ava C Wilson, Jessica M Bon, Stephanie Mason, Alejandro A Diaz, Sharon M Lutz, Raul San Jose Estepar, Gregory L Kinney, John E Hokanson, Stephen I Rennard, Richard Cas...> ;Respiratory Research. 2022 Nov 15
2 citations
Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort.
W Blake LeMaster, P Miguel Quibrera, David Couper, Donald P Tashkin, Eugene R Bleecker, Claire M Doerschuk, Victor E Ortega, Christopher Cooper, MeiLan K Han, Prescott...> ;Chest. 2023 Mar 1
26 citations
Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function.
MeiLan K Han, Wen Ye, Di Wang, Emily White, Mehrdad Arjomandi, Igor Z Barjaktarevic, Stacey-Ann Brown, Russell G Buhr, Alejandro P Comellas, Christopher B Cooper, Gera...> ;The New England Journal of Medicine. 2022 Sep 29
1 citations
Roflumilast May Increase Risk of Exacerbations When Used to Treat Poorly Controlled Asthma in People with Obesity.
Anne E Dixon, Loretta G Que, Ravi Kalhan, Mark T Dransfield, Linda Rogers, Lynn B Gerald, Monica Kraft, Jerry A Krishnan, Olivia Johnson, Heather Hazucha, Gem Roy, Jan...> ;Annals of the American Thoracic Society. 2023 Feb 1
16 citations
Time-Dependent Risk of Cardiovascular Events Following an Exacerbation in Patients With Chronic Obstructive Pulmonary Disease: Post Hoc Analysis From the IMPACT Trial.
Mark T Dransfield, Gerard J Criner, David M G Halpin, MeiLan K Han, Benjamin Hartley, Ravi Kalhan, Peter Lange, David A Lipson, Fernando J Martinez, Dawn Midwinter, Da...> ;Journal of the American Heart Association. 2022 Sep 20
131 citations
Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission.
Daiana Stolz, Takudzwa Mkorombindo, Desiree M Schumann, Alvar Agusti, Samuel Y Ash, Mona Bafadhel, Chunxue Bai, James D Chalmers, Gerard J Criner, Shyamali C Dharmage,...> ;Lancet. 2022 Sep 17
3 citations
Effect of chronic mucus hypersecretion on treatment responses to inhaled therapies in patients with chronic obstructive pulmonary disease: Post hoc analysis of the IMP...
Philip J Thompson, Gerard J Criner, Mark T Dransfield, David M G Halpin, MeiLan K Han, David A Lipson, Ghassan J Maghzal, Fernando J Martinez, Dawn Midwinter, Dave Sin...> ;Respirology. 2022 Dec 1
2 citations
Acute Exacerbations Are Associated with Progression of Emphysema.
Surya P Bhatt, Sandeep Bodduluri, Mark T Dransfield, Joseph M Reinhardt, James D Crapo, Edwin K Silverman, Stephen Humphries, David A Lynch, Matthew J Strand> ;Annals of the American Thoracic Society. 2022 Dec 1
6 citations
Comparing Racial Differences in Emphysema Prevalence Among Adults With Normal Spirometry: A Secondary Data Analysis of the CARDIA Lung Study.
Gabrielle Y Liu, Sadiya S Khan, Laura A Colangelo, Daniel Meza, George R Washko, Peter H S Sporn, David R Jacobs Jr, Mark T Dransfield, Mercedes R Carnethon, Ravi Kalhan> ;Annals of Internal Medicine. 2022 Aug 1
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Journal Articles

Association of Dysanapsis with Chronic Obstructive Pulmonary Disease Among Older Adults
Alain Bertoni, Gerard Criner, Mark T Dransfield, Meilan K Han, Nadia N Hansel, Erin D Michos, Elizabeth C Oelsner, Karol E Watson, JAMA