MarkAnthonyRanalliMD

Pediatric Hematology & Oncology • Columbus, OH

Associate Professor, Pediatrics, Ohio State University College of Medicine

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Office
700 Childrens Dr
Columbus, OH 43205
Phone+1 614-722-3552

Fax+1 614-722-3699
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Education & Training

McGaw Medical Center of Northwestern UniversityFellowship, Pediatric Hematology/Oncology, 1995 - 1998
Children's Hospital of PhiladelphiaResidency, Pediatrics, 1989 - 1992
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1989

Certifications & Licensure

OH State Medical License 1999 - 2026
IL State Medical License 1995 - 1999
PA State Medical License 1991 - 1996
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma Start of enrollment: 2001 Oct 18
Active, not recruiting
Phase 3
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET Start of enrollment: 2007 Mar 26
Active, not recruiting
Phase 3
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Start of enrollment: 2008 Jul 17
Recruiting
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Start of enrollment: 2009 Feb 27
Recruiting
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Start of enrollment: 2004 Feb 16
Completed
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Start of enrollment: 2010 May 07
Active, not recruiting
Phase 3
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors Start of enrollment: 2010 Nov 22
Completed
Phase 2
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation Start of enrollment: 2011 Sep 01
Completed
Phase 3
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma Start of enrollment: 2011 Sep 01
Completed
Phase 1
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant Start of enrollment: 2013 Mar 21
Completed
Phase 3
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Start of enrollment: 2012 Feb 21
Active, not recruiting
Phase 3
Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients Start of enrollment: 2012 Jun 01
Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors Start of enrollment: 2012 Jun 27
Active, not recruiting
Phase 2
Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma Start of enrollment: 2013 Feb 12
Completed
Phase 2
Brentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma Start of enrollment: 2013 Jan 31
Completed
Phase 1, Phase 2
Blood Sample Markers of Reproductive Hormones in Assessing Ovarian Reserve in Younger Patients With Newly Diagnosed Lymphomas Start of enrollment: 2013 Jun 17
Active, not recruiting
Biomarker Expression in Tissue Samples From Patients With Bone Sarcomas Start of enrollment: 2009 Nov 01
Completed
Busulfan, Cyclophosphamide, and Melphalan or Busulfan and Fludarabine Phosphate Before Donor Hematopoietic Cell Transplant in Treating Younger Patients With Juvenile Myelomonocytic Leukemia Start of enrollment: 2013 Jun 24
Completed
Phase 2
Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients. Start of enrollment: 2013 Aug 20
Completed
Phase 2
Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma Start of enrollment: 2013 Nov 13
Active, not recruiting
Phase 2
Eribulin Mesylate in Treating Patients With Recurrent or Refractory Osteosarcoma Start of enrollment: 2014 Aug 01
Completed
Phase 2
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Start of enrollment: 2014 Jul 11
Active, not recruiting
Phase 2, Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma Start of enrollment: 2019 Jul 08
Active, not recruiting
Phase 2
An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL) Start of enrollment: 2019 Dec 27
Completed
Phase 2, Phase 3
NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab Start of enrollment: 2022 Sep 01
Recruiting
Phase 1, Phase 2
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Rhabdoid tumor predisposition syndrome: A historical review of treatments and outcomes for associated pediatric malignancies.
Sarah Andres, Karen Huang, Margaret Shatara, Mohamed S Abdelbaki, Mark Ranalli, Jonathan Finlay, Ajay Gupta> ;Pediatric Blood & Cancer. 2024 Mar 30
Variability in Surveillance Strategies Following Resection of Sacrococcygeal Teratoma.
Gil, L., Minneci, P. C., Minneci, P. C., Lindsay A Gil, Maria E Knaus, Joseph R Stanek, Shachi Srivatsa, Kelli N Patterson, Richard J Wood, Peter C Minneci, Mark A Ran...> ;The Journal of Surgical Research. 2024 Mar 1
1 citations
Apixaban versus no anticoagulation for the prevention of venous thromboembolism in children with newly diagnosed acute lymphoblastic leukaemia or lymphoma (PREVAPIX-AL...
Sarah H O'Brien, Vilmarie Rodriguez, Glen Lew, Jane W Newburger, Corinna L Schultz, Etan Orgel, Kimberly Derr, Mark A Ranalli, Adam J Esbenshade, Jessica Hochberg, Hyo...> ;The Lancet. Haematology. 2024 Jan 1
Long term survivor of MOZ-p300 therapy-related acute myeloid leukemia after matched unrelated donor bone marrow transplantation.
Lubna S Mehyar, Leigh Hartog, Samir B Kahwash, Rolla Abu-Arja, Mark Ranalli, Hemalatha G Rangarajan> ;Leukemia & Lymphoma. 2023 Apr 20
3 citations
EGFR internal tandem duplications in fusion-negative congenital and neonatal spindle cell tumors.
Selene C Koo, Kathleen M Schieffer, Kristy Lee, Ajay Gupta, Ruthann B Pfau, Matthew R Avenarius, Eileen Stonerock, Stephanie LaHaye, James Fitch, Bhuvana A Setty, Ryan...> ;Genes, Chromosomes & Cancer. 2023 Jan 1
3 citations
Molecular Heterogeneity in Pediatric Malignant Rhabdoid Tumors in Patients With Multi-Organ Involvement.
Katherine E Miller, Gregory Wheeler, Stephanie LaHaye, Kathleen M Schieffer, Sydney Cearlock, Lakshmi Prakruthi Rao Venkata, Alejandro Otero Bravo, Olivia E Grischow, ...> ;Frontiers in Oncology. 2022 Jan 1
9 citations
Wilms Tumor (Nephroblastoma), Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Frank M. Balis, Daniel M. Green, Clarke P. Anderson, Shelly M. Cook, Jasreman Dhillon, Kenneth Gow, Susan M. Hiniker, Rama Jasty-Rao, Chi Lin, Harold N. Lovvorn, Iain ...> ;Journal of the National Comprehensive Cancer Network. 2021 Aug 1
11 citations
Gastroblastoma with a novel EWSR1-CTBP1 fusion presenting in adolescence
, , , , , , , , , , , , , , , , , , , , , , , > ;Genes, Chromosomes & Cancer. 2021 May 26
1 citations
Longitudinal understanding of prognosis among adolescents with cancer.
Rachel S. Fisher, Ansley E Kenney, Marci Z. Fults, Samantha Manring, Erin M. Rodriguez, Leandra Desjardins, Joseph Rausch, Tammi Young-Saleme, Mark Ranalli, Kathryn Va...> ;Pediatric Blood & Cancer. 2021 Mar 1
3 citations
Functional fecal and urinary outcomes after sacrococcygeal mass resection in pediatric patients.
Hira Ahmad, Devin R. Halleran, Jon Vardanyan, Wana Mathieu, Joseph Stanek, Mark Ranalli, Marc A. Levitt, Richard J. Wood, Jennifer H. Aldrink> ;Journal of Pediatric Surgery. 2021 Feb 23
Renal Tumors in Children and Young Adults Older Than 5 Years of Age.
Sara A. Mansfield, Margaret G. Lamb, Joseph Stanek, Michael Arnold, Mark Ranalli, Jennifer H. Aldrink> ;Journal of Pediatric Hematology/oncology. 2020 May 1
7 citations
Cabozantinib for relapsed neuroblastoma: Single institution case series
Michael P. Perisa, Michael A. Storey, Keri A. Streby, Mark Ranalli, Micah Skeens, Nilay Shah> ;Pediatric Blood & Cancer. 2020 Apr 28
14 citations
Veno-occlusive disease after high-dose busulfan-melphalan in neuroblastoma.
Tal Schechter, Evelio Perez-Albuerne, Tiffany F. Lin, Meredith S. Irwin, Mohammed Sh. Essa, Ami V. Desai, Haydar Frangoul, Gregory A. Yanik, L. Lee Dupuis, David A. Ja...> ;Bone Marrow Transplantation. 2020 Mar 1
34 citations
First-in-Human Intravenous Seprehvir in Young Cancer Patients: A Phase 1 Clinical Trial.
Keri A. Streby, Mark A. Currier, Melinda Triplet, Kristy Ott, Devon J. Dishman, Michele R. Vaughan, Mark Ranalli, Bhuvana A. Setty, Micah Skeens, Stacy Whiteside, Nich...> ;Molecular Therapy. 2019 Nov 6
Multifocal Appendiceal Carcinoid Tumor in an Adolescent: A Case Report and Review of the Literature.
Hannah Rinehardt, Mark Ranalli, Karen A. Diefenbach, Michael Arnold, Allan Espinosa Morazan, Jennifer H. Aldrink> ;Journal of Pediatric Hematology/oncology. 2019 Oct 1
3 citations
Improving Quality of Chest Computed Tomography for Evaluation of Pediatric Malignancies.
Sara A. Mansfield, Michael Dykes, Brent Adler, Joshua C. Uffman, Stephen Sales, Mark Ranalli, Brian D. Kenney, Jennifer H. Aldrink> ;Pediatric Quality & Safety. 2019 Jun 13
12 citations
Clinical efficacy of cabozantinib in two pediatric patients with recurrent renal cell carcinoma.
Mary Frances Wedekind, Mark Ranalli, Nilay Shah> ;Pediatric Blood & Cancer. 2017 Nov 1
4 citations
Renal Tumors in Children Younger Than 12 Months of Age: A 65-Year Single Institution Review.
Margaret G. Lamb, Jennifer H. Aldrink, Sarah H. O'Brien, Han Yin, Michael Arnold, Mark Ranalli> ;Journal of Pediatric Hematology/oncology. 2017 Mar 1
17 citations
Global microRNA profiling for diagnostic appraisal of melanocytic Spitz tumors
Nicholas Latchana, Kelly Regan, John Harrison Howard, Jennifer H. Aldrink, Mark Ranalli, Sara B. Peters, Xiaoli Zhang, Alejandro A. Gru, Philip R. O. Payne, Lorena P. ...> ;The Journal of Surgical Research. 2016 Oct 1
9 citations
Classification of Indeterminate Melanocytic Lesions by MicroRNA Profiling
Nicholas Latchana, Sara E. Martin del Campo, Valerie P. Grignol, Jennifer R. Clark, Scott P. Albert, Jie Zhang, Lai Wei, Jennifer H. Aldrink, Kathleen Nicol, Mark Rana...> ;Annals of Surgical Oncology. 2017 Feb 1
10 citations
Pancreaticoduodenectomy outcomes in the pediatric, adolescent, and young adult population
Sara A. Mansfield, Justin B. Mahida, Mary Dillhoff, Kyle Porter, Darwin L. Conwell, Mark Ranalli, Jon P. Walker, Jennifer H. Aldrink> ;The Journal of Surgical Research. 2016 Jul 1
16 citations
Carcinoid tumors in children and adolescents: risk for second malignancies.
Karen S. Fernández, Jennifer H. Aldrink, Mark Ranalli, Frederick B. Ruymann, Donna A. Caniano> ;Journal of Pediatric Hematology/oncology. 2015 Mar 1
45 citations
Nothing but NET: A review of norepinephrine transporter expression and efficacy of 131I-mIBG therapy
Keri A. Streby, Nilay Shah, Mark Ranalli, Anne Kunkler, Timothy P. Cripe> ;Pediatric Blood & Cancer. 2015 Jan 1
14 citations
Busulfan and melphalan as consolidation therapy with autologous peripheral blood stem cell transplantation following Children's Oncology Group (COG) induction platform...
Sandeep Soni, Vinita B. Pai, Thomas G. Gross, Mark Ranalli> ;Pediatric Transplantation. 2014 Mar 1
3 citations
Fatal extraintestinal adrenal malignancy in a 12-year-old girl with familial adenomatous polyposis.
Lindsey Rauch, Steven H. Erdman, Jennifer H. Aldrink, Mark Ranalli, Vinay Prasad, Robert P. Hoffman> ;Journal of Pediatric Gastroenterology and Nutrition. 2014 Feb 1
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Journal Articles

Veno-Occlusive Disease After High-Dose Busulfan–Melphalan in Neuroblastoma
Gregory Yanik, Morris Kletzel, Stephan Grupp, David Jacobsohn, Christopher C Dvorak, Alix E Seif, Mark Ranalli, Haydar Frangoul, Nature

Hospital Affiliations

Nationwide Children's HospitalColumbus, Ohio