Marlene P Freeman MD

Professor of Psychiatry, Harvard Medical School; Assoc Director, Center for Women's Mental Health; Clinical Trials Network & Institute; Massachusetts General Hospital. Editor-in-Chief, The Journal of Clinical Psychiatry

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15 Parkman StBoston, MA 02114
Phone+1 617-724-5600
Fax+1 617-643-3080

Education & Training

University of Cincinnati Medical CenterFellowship, 1998 - 1999
Mass General Brigham/Brigham and Women's Hospital/Harvard Medical SchoolResidency, Psychiatry, 1994 - 1998
Northwestern University The Feinberg School of MedicineClass of 1994
University of WisconsinBS, Zoology, 1986 - 1990

Certifications & Licensure

MA State Medical License 1996 - 2026
AZ State Medical License 2000 - 2009
TX State Medical License 2007 - 2008
OH State Medical License 1998 - 2001
American Board of Psychiatry and Neurology Psychiatry

Awards, Honors, & Recognition

CMS Meaningful Use Stage 2 Certification Longitudinal Medical Record, Partners Healthcare System, 2013-2014, 2016
CMS Meaningful Use Stage 1 Certification Longitudinal Medical Record, Partners Healthcare System, 2013-2014, 2016
CMS Meaningful Use Stage 1 Certification Partners Longitudinal Medical Record, Partners Healthcare System, 2013-2014, 2016

Clinical Trials

Use of Omega-3 Fatty Acids for Perinatal Depression Start of enrollment: 2004 Jun 01
Completed
Phase 2
Omega-3 for Peri- and Postmenopausal Depression Start of enrollment: 2008 Nov 01
Completed
Not Applicable
Escitalopram (Lexapro) for the Treatment of Postpartum Depression Start of enrollment: 2009 Jan 01
Completed
Phase 4

Publications & Presentations

PubMed

1 citations
Recommendations for the Deprescribing of Psychotropic Medications: A Consensus Statement From the American Society of Clinical Psychopharmacology Task Force.
Joseph F Goldberg, Roger S McIntyre, Holly A Swartz, Marlene P Freeman, Rajnish Mago
JAMA Network Open. 2026-02-02
1 citations
The pregnant body project pilot RCT protocol: Preventing disordered eating behaviors in high-risk pregnant individuals.
Rachel Vanderkruik, Caroline M Frisch, Emily C Woodworth, Sophie Scharner, Stephen J Bartels
Contemporary Clinical Trials. 2025-09-01
2 citations
What Is Meant by the Term "Deprescribing," and Does It Belong in Our Lexicon?
Joseph F Goldberg, Holly A Swartz, Rajnish Mago, Roger S McIntyre, Gin S Malhi
The Journal of Clinical Psychiatry. 2025-06-02

Journal Articles

Research Paper Tachyphylaxis in Major Depressive Disorder: A Review of the Current State of Research
Gustavo Kinrys, Andrew A Nierenberg, George I Papakostas, David Mischoulon, Maurizio Fava, Marlene P Freeman, ScienceDirect
Double-Blind, Placebo-Controlled, Dose-Ranging Trial of Intravenous Ketamine as Adjunctive Therapy in Treatment-Resistant Depression (TRD)
Sanjay J Mathew, Madhukar H Trivedi, Lee C Chang, Dan V Iosifescu, Manish K Jha, Maurizio Fava, Marlene P Freeman, Cristina Cusin, James Murrough, George I Papakostas,..., Nature
Course of Major Depressive Disorder After Pregnancy and the Postpartum Period
Lee S Cohen, Vivien K Burt, Marlene P Freeman, Danna Moustafa, Depression and Anxiety

Press Mentions

Marlene Freeman, MD: Getting to the Truth About SSRIs and Pregnancy (Video)August 18th, 2025
The Phenomenology of Postpartum Psychosis: Preliminary Findings from the Massachusetts General Hospital Postpartum Psychosis ProjectMarch 2nd, 2025
No Protection Against Relapse with CBT Added to Maintenance AntidepressantsDecember 3rd, 2019

Grant Support

A Neurosteroid Intervention for Menopausal and Perimenopausal DepressionUT SOUTHWESTERN MEDICAL CENTER2018–2025
A neurosteroid intervention for menopausal and perimenopausal depressionNational Institute on Aging (NIA), NIH, R01 mechanism2018–2023
Postpartum Depression: Omega-3 FA VS PlaceboNational Institute Of Mental Health2002–2006