MartinFGrahamMD

Pediatric Gastroenterology • Richmond, VA

Pediatric Nutrition

Professor of Pediatrics, Biochemistry, Physiology, Virginia Commonwealth University

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Office
1250 E Marshall Street
Pediatrics
Richmond, VA 23298
Phone+1 804-828-2467

Fax+1 804-628-5852
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Education & Training

Case Western Reserve Univ/Univ Hosps Cleveland Med Ctr/Rainbow Babies and Childrens HospitalFellowship, Pediatric Gastroenterology, 1978 - 1980
Case Western Reserve Univ/Univ Hosps Cleveland Med Ctr/Rainbow Babies and Childrens HospitalResidency, Pediatrics, 1975 - 1978
University of Cape Town Faculty of MedicineClass of 1973

Certifications & Licensure

VA State Medical License 1980 - 2020
OH State Medical License 1978 - 1982
American Board of Pediatrics Pediatrics

Publications & Presentations

PubMed

45 citations
Isolation and Culture of Arterial Smooth Muscle Cells From Human Placenta
Courtney E. Leik, Amy Willey, Martin F. Graham, Scott W. Walsh> ;Hypertension. 2004 Apr 1
38 citations
Linoleic acid induces interleukin-8 production by Crohn's human intestinal smooth muscle cells via arachidonic acid metabolites
Mohammad A. Alzoghaibi, Scott W. Walsh, Amy Willey, Dorne R. Yager, Alpha A. Fowler, Martin F. Graham> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2004 Apr 1
4 citations
Isolation, culture, and characterization of human intestinal smooth muscle cells.
Martin F. Graham, Amy Willey> ;Methods in Molecular Medicine. 2003 Jan 1
19 citations
Human Cytomegalovirus Enhances Chemokine Production by Lipopolysaccharide-Stimulated Lamina Propria Macrophages
Tamara K. Redman, William J. Britt, C. Mel Wilcox, Martin F. Graham, Phillip D. Smith> ;The Journal of Infectious Diseases. 2002 Mar 1
198 citations
Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells.
Gang Meng, Xiping Wei, Xiaoyun Wu, Marty T. Sellers, Julie M. Decker, Zina Moldoveanu, Jan M. Orenstein, Martin F. Graham, John C. Kappes, Jiri Mestecky, George M. Sha...> ;Nature Medicine. 2002 Feb 1
242 citations
Intestinal Macrophages Lack CD14 and CD89 and Consequently Are Down-Regulated for LPS- and IgA-Mediated Activities
Phillip D. Smith, Lesley E. Smythies, Meg Mosteller-Barnum, Don A. Sibley, Michael W. Russell, Michael Merger, Marty T. Sellers, Jan M. Orenstein, Toshihide Shimada, M...> ;Journal of Immunology. 2001 Sep 1
12 citations
Redox Imbalance in Crohn's Disease Intestinal Smooth Muscle Cells Causes NF-κB-Mediated Spontaneous Interleukin-8 Secretion
Ramesh Natarajan, Shobha Ghosh, Bernard Fisher, Robert F. Diegelmann, Amy Willey, Scott W. Walsh, Martin F. Graham, Alpha A. Fowler> ;Journal of Interferon & Cytokine Research. 2001 Jun 1
6 citations
Effect of Ascorbic Acid and Its Hydrophobic Derivative Palmitoyl Ascorbate on the Redox State of Primary Human Fibroblasts.
Gennady Rosenblat, Martin F. Graham, Adi Jonas, Mark Tarshis, Shay Yehoshua Schubert, Mina Tabak, Ishak Neeman> ;Journal of Medicinal Food. 2001 Jan 1
14 citations
Increased gelsolin expression and retarded collagen lattice contraction with smooth muscle cells from Crohn's diseased intestine.
H. Paul Ehrlich, Gretchen Allison, Michael J. Page, Walter A. Kolton, Martin F. Graham> ;Journal of Cellular Physiology. 2000 Feb 1
8 citations
Palmitoyl Ascorbate: Selective Augmentation of Procollagen mRNA Expression Compared With L-Ascorbate in Human Intestinal Smooth Muscle Cells
Gennady Rosenblat, Amy Willey, Ya-nan Zhu, Adi Jonas, Robert F. Diegelmann, Ishak Neeman, Martin F. Graham> ;Journal of Cellular Biochemistry. 1999 Jun 1
41 citations
Intestinal macrophages display reduced permissiveness to human immunodeficiency virus 1 and decreased surface CCR5
Ling Li, Gang Meng, Martin F. Graham, George M. Shaw, Phillip D. Smith> ;Gastroenterology. 1999 May 1
48 citations
Recombinant Helicobacter pylori Urease Activates Primary Mucosal Macrophages
Paul R. Harris, Peter B. Ernst, Shigetada Kawabata, Hiroshi Kiyono, Martin F. Graham, Phillip D. Smith> ;The Journal of Infectious Diseases. 1998 Nov 1
38 citations
Development of pseudointima and stenosis after transjugular intrahepatic portasystemic shunts: characterization of cell phenotype and function.
Arun J. Sanyal, Melissa J. Contos, Dorn Yager, Ya-nan Zhu, Amy Willey, Martin F. Graham> ;Hepatology. 1998 Jul 1
23 citations
Corticosteroids repress the interleukin 1 beta-induced secretion of collagenase in human intestinal smooth muscle cells.
Martin F. Graham, Amy Willey, Yn Zhu, Yager, Harvey J. Sugerman, Robert F. Diegelmann> ;Gastroenterology. 1997 Dec 1
159 citations
Cleavage of Type I Procollagen by Human Mast Cell Chymase Initiates Collagen Fibril Formation and Generates a Unique Carboxyl-terminal Propeptide
Mark W. Kofford, Lawrence B. Schwartz, Norman M. Schechter, Dorne R. Yager, Robert F. Diegelmann, Martin F. Graham> ;The Journal of Biological Chemistry. 1997 Mar 14
81 citations
Isolation and purification of CD14-negative mucosal macrophages from normal human small intestine.
Phillip D. Smith, Edward N. Janoff, Meg Mosteller-Barnum, Michael Merger, Jan M. Orenstein, John F. Kearney, Martin F. Graham> ;Journal of Immunological Methods. 1997 Mar 10
43 citations
Helicobacter pylori cytotoxin induces vacuolation of primary human mucosal epithelial cells.
Paul R. Harris, Timothy L. Cover, David R. Crowe, J M Orenstein, M F Graham, M J Blaser, Phillip D. Smith> ;Infection and Immunity. 1996 Nov 1
47 citations
Interleukin 1 beta down-regulates collagen and augments collagenase expression in human intestinal smooth muscle cells
Martin F. Graham, Amy Willey, John Adams, Dorne R. Yager, Robert F. Diegelmann> ;Gastroenterology. 1996 Feb 1
35 citations
Corticosteroids Increase Procollagen Gene Expression, Synthesis, and Secretion by Human Intestinal Smooth Muscle Cells
Martin F. Graham, Amy Willey, John Adams, Robert F. Diegelmann> ;Gastroenterology. 1995 Nov 1
61 citations
Pathogenesis of intestinal strictures in Crohn's disease—an update
Martin F. Graham> ;Inflammatory Bowel Diseases. 1995 Sep 1
22 citations
Role of ascorbic acid in procollagen expression and secretion by human intestinal smooth muscle cells.
Martin F. Graham, Amy Willey, John Adams, Dorne R. Yager, Robert F. Diegelmann> ;Journal of Cellular Physiology. 1995 Feb 1
18 citations
Collagen production by human smooth muscle cells isolated during intestinal organogenesis.
Hilary A. Perr, J R Grider, A S Mills, M Kornstein, D A Turner, Robert F. Diegelmann, Martin F. Graham> ;Anatomy and Embryology. 1992 Jan 1
36 citations
31P NMR spectra of extremity sarcomas: diversity of metabolic profiles and changes in response to chemotherapy.
Jason A. Koutcher, Douglas Ballon, Martin F. Graham, John H. Healey, Ephraim S. Casper, Robert T. Heelan, Leo E. Gerweck> ;Magnetic Resonance in Medicine. 1990 Oct 1
87 citations
Transforming growth factor β1 selectively augments collagen synthesis by human intestinal smooth muscle cells
Martin F. Graham, Gene R. Bryson, Robert F. Diegelmann> ;Gastroenterology. 1990 Aug 1
40 citations
A microassay to quantitate collagen synthesis by cells in culture
Robert F. Diegelmann, Gene R. Bryson, L.C. Flood, Martin F. Graham> ;Analytical Biochemistry. 1990 May 1
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Grant Support

Intestinal Stricture Formation In Crohns DiseaseNational Institute Of Diabetes And Digestive And Kidney Diseases1994–1999
Intestinal Stricture Formation In Crohn'S DiseaseNational Institute Of Diabetes And Digestive And Kidney Diseases1986–1993
Cytoskeletal Expression In Intestinal Smooth MuscleFogarty International Center1990
Intestinal Stricture Formation In Crohn'S DiseaseNat Inst Of Arthritis, Diabetes, Digestive &Kidney Diseases1985