Saul Joseph Karpen MD Ph.D.
Pediatric Hepatology and Liver Transplantation
Professor, VCU Health
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1220 E Broad StMMRB6050Richmond, VA 23298
Phone+1 804-827-1012
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Summary
- Dr. Saul Karpen, based in Richmond, VA, is a highly specialized medical practitioner in Pediatric Gastroenterology, with subspecialties in Pediatric Hepatology and Liver Transplantation. His professional education includes a pediatric residency and a fellowship in pediatric gastroenterology, both completed at the Yale-New Haven Medical Center. Dr. Karpen has developed significant experience in treating biliary atresia, liver transplantation, and cholestasis. His research contributions are substantial, with several publications in reputable journals such as Hepatology and Hepatology Communications. He also contributes to advancements in his field by participating in relevant clinical trials. Dr. Karpen has been recognized by SuperDoctors.com as a Super Doctor and was chosen as a Top MD by Consumers Checkbook.
Education & Training
Yale-New Haven Medical CenterFellowship, Pediatric Gastroenterology, 1991 - 1994- Yale-New Haven Medical CenterResidency, Pediatrics, 1989 - 1991
Icahn School of Medicine at Mount SinaiClass of 1989
Certifications & Licensure
VA State Medical License 2023 - 2026
GA State Medical License 2011 - 2024
TX State Medical License 2000 - 2012
CT State Medical License 1991 - 2000
American Board of Pediatrics Pediatric Gastroenterology- American Board of Pediatrics Pediatric Transplant Hepatology
Awards, Honors, & Recognition
- Super Doctor SuperDoctors.com
- Top MD Consumers Checkbook
Clinical Trials
- A Prospective Database of Infants With Cholestasis Start of enrollment: 2004 Apr 21
- Biliary Atresia Study in Infants and Children Start of enrollment: 2006 May 16
- Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) Start of enrollment: 2007 Nov 30
Publications & Presentations
PubMed
- Multi-Society Expert Panel Consensus Guidance Regarding Clinical Assessment and Clinical Trial Endpoints in Adults With α-1 Antitrypsin Deficiency-Associated Liver Dis...Rohit Loomba, Virginia C Clark, Mattias Mandorfer, Marc Miravitlles, Mark Brantly
Gastroenterology. 2025-12-11 - Elevated Serum Bile Acids Predict Poor Liver Outcomes in Children With Alagille Syndrome: Results From the GALA Study Group.Carla Fiorella Murillo Perez, Shannon M Vandriel, Emmanuel M Gonzales, Jian-She Wang, Li-Ting Li
Liver International. 2025-12-01 - Stage-dependent effects of systemic ASBT inhibition in a cholestasis-induced cholemic nephropathy mouse model.Ahmed Ghallab, Maiju Myllys, Daniela González, Adrian Friebel, Zaynab Hobloss
JHEP Reports. 2025-12-01
Journal Articles
- A Randomized, Controlled, Crossover Pilot Study of Losartan for Pediatric Nonalcoholic Fatty Liver DiseaseSaul Karpen, Miriam B Vos, BioMed Central
Press Mentions
VCU Liver Institute Brings World-Class Research Directly to Patients with Advanced CareAugust 25th, 2025- Experts Recommend Medication for Pediatric MASLD ManagementApril 24th, 2025
- Mystery Hepatitis Cases in Kids Linked to Unexpected Viral SuspectJuly 25th, 2022
Grant Support
- VCU-Atlanta Center for the Childhood Liver Disease Research Network (ChiLDReN)VIRGINIA COMMONWEALTH UNIVERSITY2005–2029
- Modeling genetic contributions to biliary atresiaVIRGINIA COMMONWEALTH UNIVERSITY2023–2027
- Modeling genetic contributions to biliary atresiaVIRGINIA COMMONWEALTH UNIVERSITY2023–2027
- Cholestatic Liver Disease Consortium (Clic): Longitudinal Study Of Genetic CauseNational Center For Research Resources2010–2011
- A Randomized, Double-Blinded, Placebo-Controlled Trial Of Corticosteroid TherapyNational Center For Research Resources2009–2011
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