MassimoCristofanilliMD

PubMed

• 1 citations
  Pharmacological suppression of the OTUD4-CD73 proteolytic axis revives antitumor immunity against immune-suppressive breast cancers.
  Yueming Zhu, Anupam Banerjee, Ping Xie, Andrey A Ivanov, Amad Uddin, Qiao Jiao, Junlong J Chi, Lidan Zeng, Ji Young Lee, Yifan Xue, Xinghua Lu, Massimo Cristofanilli, ...> ;The Journal of Clinical Investigation. 2024 Mar 26
• PACE: A Randomized Phase II Study of Fulvestrant, Palbociclib, and Avelumab After Progression on Cyclin-Dependent Kinase 4/6 Inhibitor and Aromatase Inhibitor for Horm...
  Erica L Mayer, Yue Ren, Nikhil Wagle, Reshma Mahtani, Cynthia Ma, Angela DeMichele, Massimo Cristofanilli, Jane Meisel, Kathy D Miller, Yara Abdou, Elizabeth C Riley, ...> ;Journal of Clinical Oncology. 2024 Mar 21
• Prospective Evaluation of Circulating Tumor DNA using Next Generation Sequencing as a Biomarker during Neoadjuvant Chemotherapy in Localized Pancreatic Cancer.
  Dhavan Shah, Amy Wells, Madison Cox, Kevin Dawravoo, John Abad, Arlene D'Souza, Grace Suh, Robert Bayer, Sohail Chaudhry, Qiang Zhang, Massimo Cristofanilli, David Ben...> ;Annals of Surgery. 2024 Jan 23
• 3 citations
  Concurrent Tissue and Circulating Tumor DNA Molecular Profiling to Detect Guideline-Based Targeted Mutations in a Multicancer Cohort.
  Mackay, M., Ben-Shachar, R., Drews, J., Manghnani, K., Hockenberry, A., Guinney, J., Benson, A., Iams, W., Cristofanilli, M., Nimeiri, H.> ;JAMA Network Open. 2024 Jan 2
• Inflammatory breast cancer: Epidemiologic data and therapeutic results.
  Hamouda Boussen, Yosra Berrazaga, Sherif Kullab, Maroua Manai, Narjess Berrada, Nesrine Mejri, Ismail Siala, Paul H Levine, Massimo Cristofanilli> ;International Review of Cell and Molecular Biology. 2024 Jan 1
• Circulating Tumor Cells Prediction in Hormone Receptor Positive HER2-Negative Advanced Breast Cancer: A Retrospective Analysis of the MONARCH 2 Trial.
  Lorenzo Gerratana, Masha Kocherginsky, Andrew A Davis, Paolo D'Amico, Carolina Reduzzi, Fabio Puglisi, Massimo Cristofanilli> ;The Oncologist. 2024 Feb 2
• Interplay between ESR1/PIK3CA codon variants, oncogenic pathway alterations and clinical phenotype in patients with metastatic breast cancer (MBC): comprehensive circu...
  Lorenzo Gerratana, Andrew A Davis, Marko Velimirovic, Katherine Clifton, Whitney L Hensing, Ami N Shah, Charles S Dai, Carolina Reduzzi, Paolo D'Amico, Firas Wehbe, Ar...> ;Breast Cancer Research. 2023 Oct 2
• Baseline Tumor Size as Prognostic Index in Patients With Advanced Solid Tumors Receiving Experimental Targeted Agents.
  Eleonora Nicolò, Paolo Tarantino, Oriana D'Ecclesiis, Gabriele Antonarelli, Luca Boscolo Bielo, Antonio Marra, Sara Gandini, Edoardo Crimini, Federica Giugliano, Paola...> ;The Oncologist. 2024 Jan 5
• 2 citations
  The immunogram of inflammatory breast cancer.
  Carmine Valenza, Dario Trapani, Nicola Fusco, Xiaoping Wang, Massimo Cristofanilli, Naoto T Ueno, Giuseppe Curigliano> ;Cancer Treatment Reviews. 2023 Sep 1
• Circulating Tumor DNA and Unique Actionable Genomic Alterations in the Longitudinal Monitoring of Metastatic Breast Cancer: A Case ofGene Fusion.
  Eleonora Nicolò, Laura Munoz-Arcos, Elena Vagia, Paolo D'Amico, Carolina Reduzzi, Jeannine Donahue, Maroua Manai, Amir Behdad, Youbin Zhang, Giuseppe Curigliano, Ami S...> ;JCO Precision Oncology. 2023 Jul 1
• 2 citations
  Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer.
  Nurmaa K Dashzeveg, Yuzhi Jia, Youbin Zhang, Lorenzo Gerratana, Priyam Patel, Asif Shajahan, Tsogbadrakh Dandar, Erika K Ramos, Hannah F Almubarak, Valery Adorno-Cruz,...> ;Cancer Discovery. 2023 Sep 6
• Genetic Alterations Detected by Circulating Tumor DNA in HER2-Low Metastatic Breast Cancer.
  Whitney L Hensing, Lorenzo Gerratana, Katherine Clifton, Arielle J Medford, Marko Velimirovic, Ami N Shah, Paolo D'Amico, Carolina Reduzzi, Qiang Zhang, Charles S Dai,...> ;Clinical Cancer Research. 2023 Aug 15
• 2 citations
  ICAM-1-suPAR-CD11b Axis Is a Novel Therapeutic Target for Metastatic Triple-Negative Breast Cancer.
  Dong Li, Hami Hemati, Younhee Park, Rokana Taftaf, Youbin Zhang, Jinpeng Liu, Massimo Cristofanilli, Xia Liu> ;Cancers. 2023 May 12
• 1 citations
  Cyclin-Dependent Kinase 4/6 Inhibitors Beyond Progression in Metastatic Breast Cancer: A Retrospective Real-World Biomarker Analysis.
  Lorenzo Gerratana, Andrew A Davis, Marko Velimirovic, Carolina Reduzzi, Katherine Clifton, Leslie Bucheit, Whitney L Hensing, Ami N Shah, Tania Pivetta, Charles S Dai,...> ;JCO Precision Oncology. 2023 May 1
• 6 citations
  Design of SERENA-6, a phase III switching trial of camizestrant in-mutant breast cancer during first-line treatment.
  Nicholas Turner, Cynthia Huang-Bartlett, Kevin Kalinsky, Massimo Cristofanilli, Giampaolo Bianchini, Stephen Chia, Hiroji Iwata, Wolfgang Janni, Cynthia X Ma, Erica L ...> ;Future Oncology. 2023 Mar 1
• 2 citations
  Prolonging the life of people with metastatic breast cancer in routine clinical practice by adding palbociclib to an aromatase inhibitor from a real-world database ana...
  Hope S Rugo, Adam Brufsky, Xianchen Liu, Benjamin Li, Lynn McRoy, Connie Chen, Rachel M Layman, Massimo Cristofanilli, Mylin A Torres, Giuseppe Curigliano, Richard S F...> ;Future Oncology. 2023 Mar 1
• 5 citations
  Proteolytic regulation of CD73 by TRIM21 orchestrates tumor immunogenicity.
  Ziyi Fu, Siqi Chen, Yueming Zhu, Donghong Zhang, Ping Xie, Qiao Jiao, Junlong Chi, Shipeng Xu, Yifan Xue, Xinghua Lu, Xinxin Song, Massimo Cristofanilli, William J Gra...> ;Science Advances. 2023 Jan 6
• 4 citations
  Cell-of-Origin Targeted Drug Repurposing for Triple-Negative and Inflammatory Breast Carcinoma with HDAC and HSP90 Inhibitors Combined with Niclosamide.
  Udayan Bhattacharya, Mohammad Kamran, Maroua Manai, Massimo Cristofanilli, Tan A Ince> ;Cancers. 2023 Jan 4
• 6 citations
  Evaluating Elacestrant in the Management of ER-Positive, HER2-Negative Advanced Breast Cancer: Evidence to Date.
  Leticia Varella, Massimo Cristofanilli> ;Oncotargets and Therapy. 2023 Jan 1
• 1 citations
  Latest advances in clinical studies of circulating tumor cells in early and metastatic breast cancer.
  Laura S Munoz-Arcos, Eleonora Nicolò, Mara S Serafini, Lorenzo Gerratana, Carolina Reduzzi, Massimo Cristofanilli> ;International Review of Cell and Molecular Biology. 2023 Jan 1
• 2 citations
  A Phase II Single-arm Study of Palbociclib in Patients With HER2-positive Breast Cancer With Brain Metastases and Analysis of ctDNA in Patients With Active Brain Metas...
  Ami N Shah, Cesar A Santa-Maria, Dhruvika Mukhija, Nikita Shah, Anthony K Kang, Priya Kumthekar, Kirsten Burdett, Shruti Chandra, Jenny Chang, Dean Tsarwhas, Jill Wood...> ;Clinical Breast Cancer. 2023 Apr 1
• 4 citations
  Circulating tumour DNA characterisation of invasive lobular carcinoma in patients with metastatic breast cancer.
  Andrew A Davis, Lorenzo Gerratana, Katherine Clifton, Arielle J Medford, Marko Velimirovic, Whitney L Hensing, Leslie Bucheit, Ami N Shah, Paolo D'Amico, Carolina Redu...> ;Ebiomedicine. 2022 Dec 1
• 14 citations
  A Multi-Center Clinical Study to Harvest and Characterize Circulating Tumor Cells from Patients with Metastatic Breast Cancer Using the ParsortixPC1 System.
  Evan N Cohen, Gitanjali Jayachandran, Richard G Moore, Massimo Cristofanilli, Julie E Lang, Joseph D Khoury, Michael F Press, Kyu Kwang Kim, Negar Khazan, Qiang Zhang,...> ;Cancers. 2022 Oct 26
• 32 citations
  Real-world study of overall survival with palbociclib plus aromatase inhibitor in HR+/HER2- metastatic breast cancer.
  Hope S Rugo, Adam Brufsky, Xianchen Liu, Benjamin Li, Lynn McRoy, Connie Chen, Rachel M Layman, Massimo Cristofanilli, Mylin A Torres, Giuseppe Curigliano, Richard S F...> ;NPJ Breast Cancer. 2022 Oct 11
• 7 citations
  Machine learning-assisted elucidation of CD81-CD44 interactions in promoting cancer stemness and extracellular vesicle integrity.
  Erika K Ramos, Chia-Feng Tsai, Yuzhi Jia, Yue Cao, Megan Manu, Rokana Taftaf, Andrew D Hoffmann, Lamiaa El-Shennawy, Marina A Gritsenko, Valery Adorno-Cruz, Emma J Sch...> ;Elife. 2022 Oct 4
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Journal Articles

• Minimal Residual Disease in Patients with Nonmetastatic Triple-Negative Breast Cancer  
  Massimo Cristofanilli, MD, JAMA Oncology
• Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer  
  Massimo Cristofanilli, MD, The New England Journal of Medicine
• From the Past to the Present: Insurer Coverage Frameworks for Next-Generation Tumor Sequencing  
  William J Gradishar, Al B Benson, Massimo Cristofanilli, Allison W Kurian, Value in Health
• Antitumor Response of an ERBB2 Amplified Inflammatory Breast Carcinoma With EGFR Mutation to the EGFR-TKI Erlotinib  
  Ali SM, Alpaugh RK, Buell JK, Stephens PJ, Yu JQ, Wu H, Hiemstra CN, Miller VA, Lipson D, Palmer GA, Ross JS, Cristofanilli M, Clin Breast Cancer, 2/1/2014
• Emergence of constitutively active estrogen receptor-alpha mutations in pretreated advanced estrogen receptor positive breast cancer  
  Jeselsohn R, Yelensky R, Buchwalter G, Frampton GM, Meric-Bernstam F, Gonzalez-Angulo AM, Ferrer-Lozano J, Perez-Fidalgo A, Cristofanilli M, Gomez H, Arteaga CL, Giltn..., Clin Cancer Res, 1/7/2014
• The Third International Inflammatory Breast Cancer Conference  
  van Golen KL, Cristofanilli M, Breast Cancer Res, 11/5/2013
• Phase I-II study of the farnesyl transferase inhibitor tipifarnib plus sequential weekly paclitaxel and doxorubicin-cyclophosphamide in HER2/neu-negative inflammatory ...  
  Andreopoulou E, Vigoda IS, Valero V, Hershman DL, Raptis G, Vahdat LT, Han HS, Wright JJ, Pellegrino CM, Cristofanilli M, Alvarez RH, Fehn K, Fineberg S, Sparano JA, Breast Cancer Res Treat, 10/1/2013
• Presence of anaplastic lymphoma kinase in inflammatory breast cancer  
  Robertson FM, Petricoin Iii EF, Van Laere SJ, Bertucci F, Chu K, Fernandez SV, Mu Z, Alpaugh K, Pei J, Circo R, Wulfkuhle J, Ye Z, Boley KM, Liu H, Moraes R, Zhang X, ..., Springerplus, 10/1/2013
• A Comparison of Epidemiology, Biology, and Prognosis of Inflammatory Breast Cancer in Japanese and US Populations  
  Natori A, Hayashi N, Soejima K, Deshpande GA, Takahashi O, Cristofanilli M, Ueno NT, Yamauchi H, Clin Breast Cancer, 9/28/2013
• EZH2 knockdown suppresses the growth and invasion of human inflammatory breast cancer cells  
  Mu Z, Li H, Fernandez SV, Alpaugh KR, Zhang R, Cristofanilli M, J Exp Clin Cancer Res, 9/1/2013
• Circulating tumor cells in metastatic colorectal cancer: do we need an alternative cutoff?  
  Gazzaniga P, Raimondi C, Gradilone A, Biondi Zoccai G, Nicolazzo C, Gandini O, Longo F, Tomao S, Lo Russo G, Seminara P, Vincenzi B, Chimenti I, Cristofanilli M, Frati..., J Cancer Res Clin Oncol, 8/1/2013
• Circulating tumor cells predict progression-free and overall survival in Chinese patients with metastatic breast cancer, HER2-positive or triple-negative (CBCSG004): a...  
  Jiang ZF, Cristofanilli M, Shao ZM, Tong ZS, Song EW, Wang XJ, Liao N, Hu XC, Liu Y, Wang Y, Zeng L, Zhang M, Ann Oncol, 7/14/2013
• Circulating tumor DNA to monitor metastatic breast cancer  
  Cristofanilli M, Fortina P, N Engl J Med, 7/4/2013
• Inflammatory breast cancer (IBC): clues for targeted therapies  
  Fernandez SV, Robertson FM, Pei J, Aburto-Chumpitaz L, Mu Z, Chu K, Alpaugh RK, Huang Y, Cao Y, Ye Z, Cai KQ, Boley KM, Klein-Szanto AJ, Devarajan K, Addya S, Cristofa..., Breast Cancer Res Treat, 7/1/2013
• Clinical relevance of cancer stem cells in bone marrow of early breast cancer patients  
  Giordano A, Gao H, Cohen EN, Anfossi S, Khoury J, Hess K, Krishnamurthy S, Tin S, Cristofanilli M, Hortobagyi GN, Woodward WA, Lucci A, Reuben JM, Ann Oncol, 6/24/2013
• Genome Wide Proteomics of ERBB2 and EGFR and Other Oncogenic Pathways in Inflammatory Breast Cancer  
  Zhang EY, Cristofanilli M, Robertson F, Reuben JM, Mu Z, Beavis RC, Im H, Snyder M, Hofree M, Ideker T, Omenn GS, Fanayan S, Jeong SK, Paik YK, Zhang AF, Wu SL, Hancoc..., J Proteome Res, 6/7/2013
• Outcomes After Multidisciplinary Treatment of Inflammatory Breast Cancer in the Era of Neoadjuvant HER2-directed Therapy  
  Tsai CJ, Li J, Gonzalez-Angulo AM, Allen PK, Woodward WA, Ueno NT, Lucci A, Krishnamurthy S, Gong Y, Yang W, Cristofanilli M, Valero V, Buchholz TA, Am J Clin Oncol, 5/2/2013
• Genomic and expression analysis of microdissected inflammatory breast cancer  
  Woodward WA, Krishnamurthy S, Yamauchi H, El-Zein R, Ogura D, Kitadai E, Niwa S, Cristofanilli M, Vermeulen P, Dirix L, Viens P, van Laere S, Bertucci F, Reuben JM, Ue..., Breast Cancer Res Treat, 4/1/2013
• An integrated analysis of three distinct IBC/nIBC Affymetrix gene expression data sets: uncovering the molecular secrets of IBC-biology  
  Van Laere S, Ueno NT, Finetti P, Vermeulen P, Lucci A, Robertson FM, Iwamoto T, Van Dam P, Woodward WA, Cristofanilli M, Birnbaum D, Viens P, Dirix L, Reuben JM, Bertu..., Clin Cancer Res, 2/8/2013
• Establishment and validation of circulating tumor cell-based prognostic nomograms in first-line metastatic breast cancer patients  
  Giordano A, Egleston BL, Hajage D, Bland J, Hortobagyi GN, Reuben JM, Pierga JY, Cristofanilli M, Bidard FC, Clin Cancer Res, 1/22/2013
• A Chromosome-centric Human Proteome Project (C-HPP) to Characterize the Sets of Proteins Encoded in Chromosome 17  
  Liu S, Im H, Bairoch A, Cristofanilli M, Chen R, Deutsch EW, Dalton S, Fenyo D, Fanayan S, Gates C, Gaudet P, Hincapie M, Hanash S, Kim H, Jeong SK, Lundberg E, Mias G..., J Proteome Res, 1/4/2013
• The class I HDAC inhibitor Romidepsin targets inflammatory breast cancer tumor emboli and synergizes with paclitaxel to inhibit metastasis  
  Robertson FM, Chu K, Boley KM, Ye Z, Liu H, Wright MC, Moraes R, Zhang X, Green TL, Barsky SH, Heise C, Cristofanilli M, J Exp Ther Oncol, 1/1/2013
• A randomized phase II study of lapatinib + pazopanib versus lapatinib in patients with HER2+ inflammatory breast cancer  
  Cristofanilli M, Johnston SR, Manikhas A, Gomez HL, Gladkov O, Shao Z, Safina S, Blackwell KL, Alvarez RH, Rubin SD, Ranganathan S, Redhu S, Trudeau ME, Breast Cancer Res Treat, 12/13/2012
• Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancer  
  Giordano A, Gao H, Anfossi S, Cohen E, Mego M, Lee BN, Tin S, De Laurentiis M, Parker CA, Alvarez RH, Valero V, Ueno NT, De Placido S, Mani SA, Esteva FJ, Cristofanill..., Mol Cancer Ther, 11/1/2012
• Dynamic changes of live/apoptotic circulating tumour cells as predictive marker of response to sunitinib in metastatic renal cancer  
  Rossi E, Fassan M, Aieta M, Zilio F, Celadin R, Borin M, Grassi A, Troiani L, Basso U, Barile C, Sava T, Lanza C, Miatello L, Jirillo A, Rugge M, Indraccolo S, Cristof..., Br J Cancer, 10/9/2012
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