MathulaThangarajhMD

Child Neurology • Washington, DC

Director, Neuromuscle Section, Co-Director, Pediatric MDA Clinic Children's National Medical Center

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Office
111 Michigan Ave Nw
Washington, DC 20010
Phone+1 202-476-5000
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Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Neuromuscular Medicine (Neurology), 2012 - 2013
Washington University/B-JH/SLCH ConsortiumFellowship, Child Neurology, 2009 - 2012
Washington University/B-JH/SLCH ConsortiumResidency, Pediatrics, 2007 - 2009
Christian Medical College VelloreClass of 1996

Certifications & Licensure

VA State Medical License 2019 - 2024
DC State Medical License 2013 - 2018
MO State Medical License 2010 - 2014
American Board of Psychiatry and Neurology Neurology with Special Qualification in Child Neurology
American Board of Psychiatry and Neurology Neuromuscular Medicine

Clinical Trials

Longitudinal Study of the Natural History of Duchenne Muscular Dystrophy (DMD) Start of enrollment: 2005 Dec 01
Unknown status
Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping Start of enrollment: 2012 Apr 01
Unknown status

Publications & Presentations

PubMed

1 citations
Findings from the Longitudinal CINRG Becker Natural History Study.
Paula R Clemens, Heather Gordish-Dressman, Gabriela Niizawa, Ksenija Gorni, Michela Guglieri, Anne M Connolly, Matthew Wicklund, Tulio Bertorini, Jean Mah, Mathula Tha...> ;Journal of Neuromuscular Diseases. 2024 Jan 1
1 citations
Association between neurodevelopmental impairments and motor function in Duchenne muscular dystrophy.
Mathula Thangarajh, Michael P McDermott, Michela Guglieri, Robert C Griggs> ;Annals of Clinical and Translational Neurology. 2023 Dec 1
40 citations
Effect of Different Corticosteroid Dosing Regimens on Clinical Outcomes in Boys With Duchenne Muscular Dystrophy: A Randomized Clinical Trial.
Michela Guglieri, Kate Bushby, Michael P McDermott, Kimberly A Hart, Rabi Tawil, William B Martens, Barbara E Herr, Elaine McColl, Chris Speed, Jennifer Wilkinson, Jan...> ;JAMA. 2022 Apr 19
4 citations
Rasch Analysis of the Pediatric Quality of Life Inventory 4.0 Generic Core Scales Administered to Patients With Duchenne Muscular Dystrophy
Erik Landfeldt, Joel Iff, E. Henricson, V. Vishwanathan, S. Chidambaranathan, W. Douglas Biggar, Laura McAdam, Jean K. Mah, Mar Tulinius, Avital Cnaan, Lauren P. Morge...> ;Value in Health. 2021 Oct 1
1 citations
Longitudinal motor function in proximal versus distal DMD pathogenic variants
Mathula Thangarajh, Luca Bello, Heather Gordish-Dressman, Cinrg-Dnhs Investigators> ;Muscle & Nerve. 2021 Jul 23
4 citations
Health related quality of life in young, steroid-naïve boys with Duchenne muscular dystrophy.
Craig Campbell, Elaine McColl, Michael P. McDermott, William B. Martens, Michela Guglieri, Robert C. Griggs, Volker Straub, Anne-Marie Childs, Emma Ciafaloni, Perry B....> ;Neuromuscular Disorders. 2021 Jun 10
Dystrophic muscle distribution in late-stage muscular dystrophy.
Celeste Michelle Pilato, Melissa Sue Walker, Andrea M Nguyen, McKay Elizabeth Hanna, Scott Lanxing Huang, Erika Morgan Lutins, M. Alex Meredith, Peter J. Haar, Mathula...> ;Autopsy & Case Reports. 2020 Nov 20
11 citations
Multi-Omics Identifies Circulating miRNA and Protein Biomarkers for Facioscapulohumeral Dystrophy
Christopher R. Heier, Aiping Zhang, Nhu Y. Nguyen, Christopher B. Tully, Aswini Panigrahi, Heather Gordish-Dressman, Sachchida Nand Pandey, Michela Guglieri, Monique M...> ;Journal of Personalized Medicine. 2020 Nov 19
7 citations
Longitudinal Evaluation of Working Memory in Duchenne Muscular Dystrophy
Mathula Thangarajh, Gary Elfring, Panayiota Trifillis> ;Journal of Clinical Medicine. 2020 Sep 11
11 citations
The CINRG Becker Natural History Study: Baseline characteristics
Paula R. Clemens, Gabriela Niizawa, Jia Feng, Julaine Florence, Andrea Smith DʼAlessandro, Lauren P. Morgenroth, Ksenija Gorni, Michela Guglieri, Anne M. Connolly, Mat...> ;Muscle & Nerve. 2020 Sep 1
12 citations
249th ENMC International Workshop: The role of brain dystrophin in muscular dystrophy: Implications for clinical care and translational research, Hoofddorp, The Nether...
Jos G.M. Hendriksen, Mathula Thangarajh, Hermien E. Kan, Francesco Muntoni> ;Neuromuscular Disorders. 2020 Aug 15
11 citations
The NIH Toolbox for cognitive surveillance in Duchenne muscular dystrophy
Mathula Thangarajh, Aaron J. Kaat, Genila Bibat, Jennifer Mansour, Katherine Summerton, Anthony Gioia, Carly Berger, Kristina K. Hardy, Kathryn R. Wagner> ;Annals of Clinical and Translational Neurology. 2019 Sep 1
5 citations
Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse model for Duchenne.
Mathula Thangarajh, Aiping Zhang, Kirandeep Gill, Habtom W. Ressom, Zhenzhi Li, Rency S. Varghese, Eric P. Hoffman, Kanneboyina Nagaraju, Yetrib Hathout, Simina M. Boca> ;Plos One. 2019 Jul 16
14 citations
Neurodevelopmental Needs in Young Boys with Duchenne Muscular Dystrophy (DMD): Observations from the Cooperative International Neuromuscular Research Group (CINRG) DMD...
Mathula Thangarajh, Christopher F. Spurney, Heather Gordish-Dressman, Paula R. Clemens, Eric P. Hoffman, Craig M. McDonald, Erik K Henricson, Cinrg Investigators> ;Plos Currents. 2018 Oct 17
8 citations
The relationship between deficit in digit span and genotype in nonsense mutation Duchenne muscular dystrophy.
Mathula Thangarajh, Gary Elfring, Panayiota Trifillis, Joseph McIntosh, Stuart W. Peltz> ;Neurology. 2018 Sep 25
10 citations
Recruitment & retention program for the NeuroNEXT SMA Biomarker Study: Super Babies for SMA!
Amy Bartlett, Stephen J. Kolb, Allison Kingsley, Kathryn J. Swoboda, Sandra P. Reyna, Ai Sakonju, Basil T. Darras, Richard Shell, Nancy L. Kuntz, Diana Castro, Susan T...> ;Contemporary Clinical Trials Communications. 2018 Jul 20
25 citations
A checklist for clinical trials in rare disease: obstacles and anticipatory actions—lessons learned from the FOR-DMD trial
Rebecca A. Crow, Kimberly A. Hart, Michael P. McDermott, Rabi Tawil, William B. Martens, Barbara E. Herr, Elaine McColl, Jennifer Wilkinson, Janbernd Kirschner, Wendy ...> ;Trials. 2018 May 10
16 citations
A multinational study on motor function in early-onset FSHD
Jean K. Mah, Jia Feng, Marni B. Jacobs, Tina Duong, K. Carroll, Katy de Valle, Cara L. Carty, Lauren P. Morgenroth, Michela Guglieri, Monique M. Ryan, Paula R. Clemens...> ;Neurology. 2018 Apr 10
The Relationship Between Bone Mineral Density and Cardiovascular Function in Duchenne Muscular Dystrophy: A Retrospective Cohort Study.
Tara Kervin, Mathula Thangarajh> ;Plos Currents. 2018 Mar 22
246 citations
Long-term effects of glucocorticoids on function, quality of life, and survival in patients with Duchenne muscular dystrophy: a prospective cohort study
Craig M. McDonald, Erik K Henricson, Richard T. Abresch, Tina Duong, Nanette C. Joyce, F. Hu, Paula R. Clemens, Eric P. Hoffman, Avital Cnaan, Heather Gordish-Dressman...> ;Lancet. 2017 Nov 22
231 citations
Natural history of infantile-onset spinal muscular atrophy.
Stephen J. Kolb, Christopher S. Coffey, Jon W. Yankey, Kristin J. Krosschell, W. David Arnold, Seward B. Rutkove, Kathryn J. Swoboda, Sandra P. Reyna, Ai Sakonju, Basi...> ;Annals of Neurology. 2017 Dec 1
55 citations
Developing standardized corticosteroid treatment for Duchenne muscular dystrophy.
Michela Guglieri, Kate Bushby, Michael P. McDermott, Kimberly A. Hart, Rabi Tawil, William B. Martens, Barbara E. Herr, Elaine McColl, Jennifer Wilkinson, Janbernd Kir...> ;Contemporary Clinical Trials. 2017 Jul 1
13 citations
Cytoplasmic body pathology in severe ACTA1-related myopathy in the absence of typical nemaline rods
Sandra Donkervoort, Sophelia H. S. Chan, Leslie H. Hayes, Nathaniel Bradley, David P. Nguyen, M. Leach, Payam Mohassel, Ying Hu, Mathula Thangarajh, Diana Bharucha-Goe...> ;Neuromuscular Disorders. 2017 Jun 1
58 citations
Association Study of Exon Variants in the NF-κB and TGFβ Pathways Identifies CD40 as a Modifier of Duchenne Muscular Dystrophy
Luca Bello, Jaya Punetha, Heather Gordish-Dressman, Mamta Giri, Eric P. Hoffman, Andrea Barp, Sara Vianello, Elena Pegoraro, Kevin M. Flanigan, Robert B. Weiss, Pietro...> ;American Journal of Human Genetics. 2016 Nov 3
93 citations
Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study.
Stephen J. Kolb, Christopher S. Coffey, Jon W. Yankey, Kristin J. Krosschell, W. David Arnold, Seward B. Rutkove, Kathryn J. Swoboda, Sandra P. Reyna, Ai Sakonju, Basi...> ;Annals of Clinical and Translational Neurology. 2016 Feb 1
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Hospital Affiliations

Children's Hospital of Richmond at VCU-Brook Road CampusRichmond, Virginia