MatteoTruccoMD

Pediatric Hematology & Oncology • Cleveland, OH

Pediatric Hematologic Oncology, Pediatric Sarcoma Oncology, Pediatric Solid Tumor Oncology

Associate Professor of Pediatrics Cleveland Clinic Lerner College of Medicine Case Western Reserve University Cleveland Clinic Children’s Director Children’s Cancer Innovative Therapy Program

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Office
Cleveland Clinic Children's
9500 Euclid Ave, R3-111
Cleveland, OH 44195
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Summary

Dr. Matteo Trucco is a pediatric hematologist/oncologist at the Cleveland Clinic in Cleveland, OH specializing in pediatric sarcomas and the development on new treatments for childhood cancers. He received his medical degree from Temple University School of Medicine and has been in practice 11 years. He also speaks multiple languages, including Spanish and Italian. He is involved in several organization whose mission is to improve the outcomes for children battling cancer including the National Pediatric Cancer Foundation, MIB Agents and the SebastianStrong Foundation.

Education & Training

Johns Hopkins UniversityFellowship, Pediatric Hematology/Oncology, 2009 - 2012
Case Western Reserve University - University HospitalsResidency, Pediatrics, 2006 - 2009
Temple University School of MedicineClass of 2006
University of PennsylvaniaBA, Biology, Philosophy of Science, 1997 - 2001

Certifications & Licensure

FL State Medical License 2016 - 2020
TX State Medical License 2012 - 2017
MD State Medical License 2009 - 2013
OH State Medical License 2006 - 2021
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma Start of enrollment: 2012 Aug 01Cohn, S.L.,Trucco, M.,Pinto, N.R.,Leavey, P.J.,Druta, M.,Borinstein, S.C.,Spunt, S.L.,Arndt, C.A.,Keedy, V.,Mascarenhas, L.,Werger, A.,Gill, J.,Shusterman, S.,Gorlick, R.G.,Sossaman, G.N.,Meyers, P.A.,Wri...
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations Zachary Zimmerman, M.D.
Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas Matteo Trucco, MD
Dendritic Cell Vaccine With or Without Gemcitabine Pre-Treatment for Adults and Children With Sarcoma Matteo Trucco, MD

Publications & Presentations

PubMed

An evolutionary framework for treating pediatric sarcomas
Damon R. Reed, Jonathan Metts, Mariyah Pressley, Brooke L. Fridley, Masanori Hayashi, Michael S. Isakoff, David M. Loeb, Rikesh Makanji, Ryan D. Roberts, Matteo Trucco...> ;Cancer. 2020 Mar 16
Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial.
Wilky, B. A., Trucco, M. M., Subhawong, T. K., Florou, V., Park, W., Kwon, D., Wieder, E. D., Kolonias, D., Rosenberg, A. E., Kerr, D. A., Sfakianaki, E., Foley, M., M...> ;The Lancet. Oncology. 2019 May 13
A phase II study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcomas.
Trucco, M. M.,Meyer, C. F.,Thornton, K. A.,Shah, P.,Chen, A. R.,Wilky, B. A.,Carrera-Haro, M. A.,Boyer, L. C.,Ferreira, M. F.,Shafique, U.,Powell, J. D.,Loeb, D. M.> ;Clin Sarcoma Res. 2018 Nov 10
A phase I window, dose escalating and safety trial of metformin in combination with induction chemotherapy in relapsed refractory acute lymphoblastic leukemia: Metform...
Trucco, M., Barredo, J. C., Goldberg, J. M., Leclerc, G. M., Hale, G. A., Gill, J., Setty, B. A., Smith, T., Lush, R. M., Lee, J. K., Reed, D. R.> ;Pediatric blood & cancer. 2018 Jun 2
Metabolic modulation of Ewing sarcoma cells inhibits tumor growth and stem cell properties
Atreyi Dasgupta, Matteo Trucco, Nino Rainusso, Ronald J. Bernardi, Ryan Shuck, Lyazat Kurenbekova, David M. Loeb, Jason T. Yustein> ;Oncotarget. 2017 Aug 26
A monoclonal antibody against the Wnt signaling inhibitor dickkopf-1 inhibits osteosarcoma metastasis in a preclinical model.
Seth D. Goldstein, Matteo Trucco, Wendy Bautista Guzman, Masanori Hayashi, David M. Loeb> ;Oncotarget. 2016 Apr 1
Coamplification of Myc/Pvt1 and homozygous deletion of Nlrp1 locus are frequent genetics changes in mouse osteosarcoma.
Rao, P. H., Zhao, S., Zhao, Y., Yu, A., Rainusso, N., Trucco, M., Allen-Rhoades, W., Satterfield, L., Fuja, D., Borra, V. J., Man, T., Donehower, L. A., Yustein, J. T.> ;Genes, chromosomes & cancer. 2015 Sep 12
Retrospective cohort study comparing activated partial thromboplastin time versus anti-factor Xa activity nomograms for therapeutic unfractionated heparin monitoring i...
Trucco M, Lehmann CU, Mollenkopf N, Streiff MB, Takemoto CM> ;Journal of thrombosis and haemostasis : JTH. 2015-04-13
1 citation
Cross-species identification of a plasma microRNA signature for detection, therapeutic monitoring, and prognosis in osteosarcoma.
Allen-Rhoades, W., Kurenbekova, L., Satterfield, L., Parikh, N., Fuja, D., Shuck, R. L., Rainusso, N., Trucco, M., Barkauskas, D. A., Jo, E., Ahern, C. H., Hilsenbeck,...> ;Cancer medicine. 2015 Mar 19
1 citation
A novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-ÎºB signaling in chordoma biology.
Trucco, M. M., Awad, O., Wilky, B. A., Goldstein, S. D., Huang, R., Walker, R. L., Shah, P., Katuri, V., Gul, N., Zhu, Y. J., McCarthy, E. F., Paz-Priel, I., Meltzer, ...> ;PloS one. 2013 Nov 14
A dose finding study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcoma.
Thornton, K. A.,Chen, A. R.,Trucco, M. M.,Shah, P.,Wilky, B. A.,Gul, N.,Carrera-Haro, M. A.,Ferreira, M. F.,Shafique, U.,Powell, J. D.,Meyer, C. F.,Loeb, D. M.> ;Int J Cancer. 2013 Aug 15
Sarcoma stem cells: do we know what we are looking for?
Trucco, M.,Loeb, D.> ;Sarcoma. 2012 Jun 02
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Press Mentions

SebastianStrong Awards $225,000 Discovery Science Grant for Childhood Brain Cancer ResearchAugust 08, 2020 09:35
Your Child Has Been Diagnosed with Cancer. Don’t Panic. Smart Treatments AboundJuly 28, 2018 17:07
Bumps That Won’t Go Away Sometimes Signal More Serious Medical TroubleMay 30, 2017 10:31