MatthewH.CarabasiMD

Oncology • Philadelphia, PA

Hematologic Oncology

Stem Cell Transplantation

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Office
925 Chestnut St
# 420A
Philadelphia, PA 19107
Phone+1 215-955-8874

Fax+1 215-955-2340
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Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 1985 - 1989
Drexel University College of Medicine/Hahnemann University HospitalResidency, Internal Medicine, 1980 - 1983
Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1980

Certifications & Licensure

CA State Medical License 2000 - Present
PA State Medical License 1982 - 2024
NJ State Medical License 2017 - 2023
DE State Medical License 2017 - 2021
AL State Medical License Active through 2000
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Patient-Centered Specialty Practice Recognition Program National Committee for Quality Assurance, 2014-2017
America's Top Doctors Castle Connolly, 2009-2014
Philadelphia Magazine Castle Connolly, 2008-2014
America's Top Doctors for Cancer Castle Connolly, 2008-2013
CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2011-2013
Super Doctor SuperDoctors.com
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Clinical Trials

Study of VELCADE® With Mitoxantrone and Etoposide for Leukemias Start of enrollment: 2006 Jan 01
Completed
Phase 1, Phase 2
Safety and Efficacy Study of Immunotherapy With Rituximab and Interleukin-2 in Patients With Non-Hodgkin's Lymphoma Start of enrollment: 2009 Feb 05
Completed
Phase 2
A Study of Bone Marrow Transplantation Using Fully-Matched Relatives as Donors for Patients With Hematological Malignancies Start of enrollment: 2008 Apr 10
Completed
Phase 2
A Research Study of Bone Marrow Transplantation From Unrelated or Partially Matched Related Donors Start of enrollment: 2011 Feb 10
Completed
Phase 2
Treatment of Sickle Cell Anemia With Stem Cell Transplant Start of enrollment: 2009 Sep 01
Terminated
Not Applicable
Combination of Pentostatin, Bendamustine and Ofatumumab for Treatment of Chronic Lymphocytic Leukemia and Lymphoma Start of enrollment: 2011 May 25
Terminated
Phase 1
A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies Start of enrollment: 2011 Aug 04
Completed
Phase 2
Phase I/II Study of Bendamustine in Combination With Ofatumumab, Carboplatin and Etoposide Start of enrollment: 2011 Nov 09
Completed
Phase 1, Phase 2
Donor Stem Cell Boost in Treating Patients With Low Blood Cells After Donor Stem Cell Transplant Start of enrollment: 2012 Aug 01
Withdrawn
Not Applicable
Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies Start of enrollment: 2012 Dec 24
Completed
Phase 2
Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2013 Mar 15
Completed
Early Phase 1
Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy Start of enrollment: 2013 Jul 08
Active, not recruiting
Phase 2
Haploidentical Donor Hematopoietic Stem Cell Transplant in Treating Patients With Hematologic Malignancies Start of enrollment: 2013 May 17
Terminated
Phase 2
Allogeneic Hematopoietic Stem Cell Transplantation for High-Risk Hematologic Malignancies Using One Haploidentical Donor Start of enrollment: 2013 Nov 04
Completed
Phase 2
Bendamustine Hydrochloride, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma Start of enrollment: 2014 Aug 25
Completed
Phase 2
ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS) Start of enrollment: 2019 Aug 20
Recruiting
Phase 1
A Study of CART-PSMA-TGFβRDN in Patients With Metastatic Castration Resistant Prostate Cancer Start of enrollment: 2019 Nov 22
Terminated
Phase 1
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Publications & Presentations

PubMed

A Phase I Trial of Sirolimus with "7&3" Induction Chemotherapy in Patients with Newly Diagnosed Acute Myeloid Leukemia.
Neil Palmisiano, Grace Jeschke, Lindsay Wilde, Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O'Hara, Dolores Grosso, Thomas Klumpp, Ubaldo Martinez, John Wagner, Ma...> ;Cancers. 2023 Oct 25
A Prospective, Randomized Trial Examining the Use of G-CSF Versus No G-CSF in Patients Post-Autologous Transplantation.
Dolores Grosso, Benjamin Leiby, Lindsay Wilde, Matthew Carabasi, Joanne Filicko-O'Hara, William O'Hara, John L Wagner, Gina Mateja, Onder Alpdogan, Adam Binder, Margar...> ;Transplantation and Cellular Therapy. 2022 Dec 1
2 citations
Outcomes of two-step haploidentical allogeneic stem cell transplantation in elderly patients with hematologic malignancies.
Xia Bi, Usama Gergis, John L Wagner, Matthew Carabasi, Joanne Filicko-O'Hara, William O'Hara, Thomas Klumpp, Pierluigi Porcu, Neal Flomenberg, Dolores Grosso> ;Bone Marrow Transplantation. 2022 Nov 1
2 citations
The Two-Step Allogeneic Stem Cell Transplantation Approach Results in Rapid Engraftment and Excellent Outcomes in Patients with Lymphoid Malignancies.
Yang Yang, Usama Gergis, Matthew Carabasi, Joanne Filicko-O'Hara, John L Wagner, William O'Hara, Adam Binder, Onder Alpdogan, Ubaldo Martinez-Outschoorn, Pierluigi Por...> ;Transplantation and Cellular Therapy. 2022 Mar 1
2 citations
An Examination of Cytomegalovirus, Socioeconomic Status, Race, and Ethnicity on Outcomes after Haploidentical Hematopoietic Transplantation.
Chetan Jeurkar, Benjamin E. Leiby, Joshua Banks, Amy Leader, Shannon Rudolph, Gina Mateja, Shaik Rashid, Matthew Carabasi, Joanne Filicko-O'Hara, William O'Hara, John ...> ;Transplantation and Cellular Therapy. 2021 Apr 1
1 citations
Phase I/II study of bendamustine in combination with ofatumumab, carboplatin, etoposide (BOCE) for relapsed or refractory aggressive B-cell non-Hodgkin lymphoma.
Jonathan Pan, Sushil Ghimire, S. Onder Alpdogan, Andrew E. Chapman, Matthew Carabasi, Martina DiMeglio, Jerald Z. Gong, Ubaldo E. Martinez-Outschoorn, Lewis J. Rose, M...> ;Leukemia & Lymphoma. 2021 Feb 23
2 citations
Low Nonrelapse Mortality after HLA-Matched Related 2-Step Hematopoietic Stem Cell Transplantation Using Cyclophosphamide for Graft-versus-Host Disease Prophylaxis and ...
Dolores Grosso, Matthew Carabasi, Joanne Filicko-O'Hara, John L. Wagner, William O'Hara, Michael Sun, Beth W. Colombe, Wenyin Shi, Maria Werner-Wasik, Shannon Rudolph,...> ;Biology of Blood and Marrow Transplantation. 2020 Oct 1
10 citations
The Presence of a CMV Immunodominant Allele in the Recipient Is Associated With Increased Survival in CMV Positive Patients Undergoing Haploidentical Hematopoietic Ste...
Dolores Grosso, Benjamin E. Leiby, Matthew Carabasi, Joanne Filicko-O'Hara, Sameh Gaballa, William O'Hara, John L. Wagner, Neal Flomenberg> ;Frontiers in Oncology. 2019 Sep 17
5 citations
Autologous Stem Cell Transplantation for Multiple Myeloma: Growth Factor Matters
Jason Chen, Jonathan Pan, Tingting Zhan, Sherilyn A. Tuazon, Neeraj Saini, William O'Hara, Joanne Filicko-O'Hara, Thomas R. Klumpp, Margaret Kasner, Matthew Carabasi, ...> ;Biology of Blood and Marrow Transplantation. 2019 Sep 1
13 citations
Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition
Margaret Kasner, Rosemarie Mick, Grace R. Jeschke, Matthew Carabasi, Joanne Filicko-O'Hara, Neal Flomenberg, Noelle V. Frey, Elizabeth O. Hexner, Selina M. Luger, Alis...> ;Investigational New Drugs. 2018 Apr 2
3 citations
Higher rates of relapse in maternal recipients of haploidentical hematopoietic stem cell transplantation from adult offspring donors for AML and myelodysplastic syndrome.
Praveen Ramakrishnan Geethakumari, Benjamin E. Leiby, Rasmi G. Nair, Seyfettin Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O'Hara, Sameh Gaballa, Margaret Kasner,...> ;Bone Marrow Transplantation. 2017 Oct 1
65 citations
Improved survival after acute graft- versus -host disease diagnosis in the modern era.
Hanna Jean Khoury, Tao Wang, Michael T. Hemmer, Daniel R. Couriel, Amin M. Alousi, Corey Cutler, Mahmoud Aljurf, Joseph H. Antin, Mouhab Ayas, Minoo Battiwalla, Jean-Y...> ;Haematologica. 2017 May 1
12 citations
Acquired uniparental disomy in chromosome 6p as a feature of relapse after T-cell replete haploidentical hematopoietic stem cell transplantation using cyclophosphamide...
Dolores Grosso, Erica S. Johnson, Beth W. Colombe, Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O'Hara, Sameh Gaballa, Margaret Kasner, Thomas R. Klumpp, Ubaldo E....> ;Bone Marrow Transplantation. 2017 Jan 9
19 citations
A Two-Step Haploidentical Versus a Two-Step Matched Related Allogeneic Myeloablative Peripheral Blood Stem Cell Transplantation
Sameh Gaballa, Neil Palmisiano, Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O'Hara, Margaret Kasner, Walter K. Kraft, Benjamin E. Leiby, Ubaldo E. Martinez-Outsch...> ;Biology of Blood and Marrow Transplantation. 2016 Jan 1
35 citations
A two-step approach to myeloablative haploidentical transplantation: low nonrelapse mortality and high survival confirmed in patients with earlier stage disease.
Dolores Grosso, Sameh Gaballa, Onder Alpdogan, Matthew Carabasi, Joanne Filicko-O'Hara, Margaret Kasner, Ubaldo E. Martinez-Outschoorn, John L. Wagner, William O'Hara,...> ;Biology of Blood and Marrow Transplantation. 2015 Apr 1
57 citations
Clostridium difficile colonization and disease in patients undergoing hematopoietic stem cell transplantation
Jackrapong Bruminhent, Zi-Xuan Wang, Carol Hu, John L. Wagner, Richard Sunday, Brent Bobik, Sarah E. Hegarty, Scott W. Keith, Seyfettin Onder Alpdogan, Matthew Carabas...> ;Biology of Blood and Marrow Transplantation. 2014 Sep 1
12 citations
No increased mortality from donor or recipient hepatitis B- and/or hepatitis C-positive serostatus after related-donor allogeneic hematopoietic cell transplantation
Marcie Tomblyn, Min Chen, Manisha Kukreja, M Aljurf, F. Al Mohareb, Brian J. Bolwell, J. Y. Cahn, Matthew Carabasi, Robert Peter Gale, Ronald E. Gress, Vikas Gupta, Gr...> ;Transplant Infectious Disease. 2012 Oct 1
12 citations
Allogeneic Hematopoietic Cell Transplantation for Advanced Polycythemia Vera and Essential Thrombocythemia
Karen K. Ballen, Ann E. Woolfrey, Xiaochun Zhu, Kwang Woo Ahn, Baldeep Wirk, Mukta Arora, Biju George, Bipin N. Savani, Brian J. Bolwell, David L. Porter, Ed Copelan, ...> ;Biology of Blood and Marrow Transplantation. 2012 Sep 1
63 citations
A 2-step approach to myeloablative haploidentical stem cell transplantation: a phase 1/2 trial performed with optimized T-cell dosing
Dolores Grosso, Matthew Carabasi, Joanne Filicko-O'Hara, Margaret Kasner, John L. Wagner, Beth W. Colombe, Patricia Cornett Farley, William O'Hara, Phyllis Flomenberg,...> ;Blood. 2011 Oct 27
144 citations
Reducing the Risk for Transplantation-Related Mortality After Allogeneic Hematopoietic Cell Transplantation: How Much Progress Has Been Made?
John T. Horan, Brent R. Logan, Manza A. Agovi-Johnson, Hillard M. Lazarus, Andrea Bacigalupo, Karen K. Ballen, Christopher Bredeson, Matthew Carabasi, Vikas Gupta, Gre...> ;Journal of Clinical Oncology. 2011 Mar 1
12 citations
Adenovirus DNA polymerase is recognized by human CD8+ T cells.
Amita Joshi, Jie Tang, Melanie Kuzma, John E. Wagner, Bijoyesh Mookerjee, Joanne Filicko, Matthew Carabasi, Neal Flomenberg, Phyllis Flomenberg> ;The Journal of General Virology. 2009 Jan 1
96 citations
Impact of prior imatinib mesylate on the outcome of hematopoietic cell transplantation for chronic myeloid leukemia
Stephanie J. Lee, Manisha Kukreja, Tao Wang, Sergio Giralt, Jeff Szer, Mukta Arora, Ann E. Woolfrey, Francisco Cervantes, Richard E. Champlin, Robert Peter Gale, Joerg...> ;Blood. 2008 Oct 15
Phase I trial of bortezomib, mitoxantrone and etoposide in relapsed/refractory acute leukemia.
Filicko-O'Hara J, Mookerjee B, Carabasi MH, Besa E, Wagner JL, Flomenberg N> ;J. Clin. Oncol.. 2008-05-20
134 citations
A phase 1 multidose study of SGN-30 immunotherapy in patients with refractory or recurrent CD30+ hematologic malignancies.
Nancy L. Bartlett, Anas Younes, Matthew Carabasi, Andres Forero, Joseph D. Rosenblatt, John P. Leonard, Steven H. Bernstein, R. Gregory Bociek, Jennie M. Lorenz, Bruce...> ;Blood. 2008 Feb 15
46 citations
Improved Outcomes in Intermediate- and High-Risk Aggressive Non-Hodgkin Lymphoma after Autologous Hematopoietic Stem Cell Transplantation Substituting Intravenous for ...
Charu Aggarwal, Sameer Gupta, William P. Vaughan, Gene Saylors, Donna Salzman, Rhonda O. Katz, Amy G. Nance, Arabella B. Tilden, Matthew Carabasi> ;Biology of Blood and Marrow Transplantation. 2006 Jul 1
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