MatthewJohnKolarMDPhD

PubMed

• 131 citations
  Serine restriction alters sphingolipid diversity to constrain tumour growth.
  Thangaselvam Muthusamy, Thekla Cordes, Michal K. Handzlik, Le You, Esther W. Lim, Jivani M. Gengatharan, Antonio Pinto, Mehmet G. Badur, Matthew J. Kolar, Martina Wall...> ;Nature. 2020 Aug 12
• 52 citations
  The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina.
  Daniel Chen, Daniel L. Chao, Lorena Raquel Rocha, Matthew J. Kolar, Viet Anh Nguyen Huu, Michal Krawczyk, Manish Dasyani, Tina Wang, Maryam Jafari, Mary Jabari, K. Ros...> ;Aging Cell. 2020 Jan 14
• 5 citations
  Stereochemistry of Linoleic Acid Esters of Hydroxy Linoleic Acids.
  Huijing Wang, Matthew J. Kolar, Tina Chang, José Rizo, Srihari Konduri, Clare McNerlin, Alan Saghatelian, Dionicio Siegel> ;Organic Letters. 2019 Sep 23
• 45 citations
  Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals
  Matthew J. Kolar, Srihari Konduri, Tina Chang, Huijing Wang, Clare McNerlin, Lena Ohlsson, Magnus Härröd, Dionicio Siegel, Alan Saghatelian> ;The Journal of Biological Chemistry. 2019 Jul 5
• 31 citations
  Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements
  Matthew J. Kolar, Andrew T. Nelson, Tina Chang, Meric Erikci Ertunc, Mitchell P. Christy, Lena Ohlsson, Magnus Härröd, Barbara B. Kahn, Dionicio Siegel, Alan Saghatelian> ;Analytical Chemistry. 2018 Mar 26
• 111 citations
  Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.
  Ismail Syed, Jennifer Lee, Pedro M. Moraes-Vieira, Cynthia J. Donaldson, Alexandra Sontheimer, Pratik Aryal, Kerry Wellenstein, Matthew J. Kolar, Andrew T. Nelson, Dio...> ;Cell Metabolism. 2018 Feb 6
• 40 citations
  Blocking Zika virus vertical transmission.
  Pinar Mesci, Angela Macia, Spencer M. Moore, Sergey A. Shiryaev, Antonella Pinto, Chun-Teng Huang, Leon Tejwani, Isabella Rodrigues Fernandes, Nicole A. Suarez, Matthe...> ;Scientific Reports. 2018 Jan 19
• 226 citations
  Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence.
  Gabriele Sulli, Amy Rommel, Xiaojie Wang, Matthew J. Kolar, Francesca Puca, Alan Saghatelian, Maksim V. Plikus, Inder M. Verma, Satchidananda Panda> ;Nature. 2018 Jan 10
• 35 citations
  Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer
  Shreya Mitra, Jeffrey E. Montgomery, Matthew J. Kolar, Gang Li, Kang Jin Jeong, Bo Peng, Gregory L. Verdine, Gordon B. Mills, Raymond E. Moellering> ;Nature Communications. 2017 Sep 22
• 45 citations
  Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation
  Andrew T. Nelson, Matthew J. Kolar, Qian Chu, Ismail Syed, Barbara B. Kahn, Alan Saghatelian, Dionicio Siegel> ;Journal of the American Chemical Society. 2017 Mar 28
• 251 citations
  Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex
  Jessica J. Howell, Kristina Hellberg, Marc Turner, George Talbott, Matthew J. Kolar, Debbie Vasquez Ross, Gerta Hoxhaj, Alan Saghatelian, Reuben J. Shaw, Brendan D. Ma...> ;Cell Metabolism. 2017 Feb 7
• 209 citations
  SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism
  Yumiko Oishi, Nathanael J. Spann, Verena M. Link, Evan D. Muse, Tobias Strid, Chantle Edillor, Matthew J. Kolar, Takashi Matsuzaka, Sumio Hayakawa, Jenhan Tao, Minna U...> ;Cell Metabolism. 2017 Feb 7
• 247 citations
  Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.
  Peiwen Chen, Hao Zuo, Hu Xiong, Matthew J. Kolar, Qian Chu, Alan Saghatelian, Daniel J. Siegwart, Yihong Wan> ;Proceedings of the National Academy of Sciences of the United States of America. 2017 Jan 17
• 317 citations
  Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models
  Robert U. Svensson, Seth J. Parker, Lillian J. Eichner, Matthew J. Kolar, Martina Wallace, Sonja N. Brun, Portia S. Lombardo, Jeanine L. Van Nostrand, Amanda Hutchins,...> ;Nature Medicine. 2016 Oct 1
• 46 citations
  Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase
  Matthew J. Kolar, Siddhesh S. Kamat, William H. Parsons, Edwin A. Homan, Tim Maher, Odile D. Peroni, Ismail Syed, Karianne Fjeld, Anders Molven, Barbara B. Kahn, Benja...> ;Biochemistry. 2016 Aug 10
• 50 citations
  AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs
  William H. Parsons, Matthew J. Kolar, Siddhesh S. Kamat, Armand B. Cognetta, Jonathan J. Hulce, Enrique Saez, Barbara B. Kahn, Alan Saghatelian, Benjamin F. Cravatt> ;Nature Chemical Biology. 2016 May 1
• 49 citations
  A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids
  Tejia Zhang, Shili Chen, Ismail Syed, Marcus Ståhlman, Matthew J. Kolar, Edwin A. Homan, Qian Chu, Ulf Smith, Jan Borén, Barbara B. Kahn, Alan Saghatelian> ;Nature Protocols. 2016 Apr 1
• Join now to see all