
Matthew J Sorrentino MD
Non-Invasive Cardiology, Preventive Cardiology
Professor of Medicine, University of Chicago Medicine
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5841 S. MARYLAND AVE.M/C 6080Chicago, IL 60637
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Summary
- Dr. Matthew Sorrentino is a cardiologist based in Chicago, IL, specializing in non-invasive and preventive cardiology. He completed his fellowship in cardiovascular disease and residency in internal medicine at the University of Chicago, where he also earned his medical degree. Additionally, he holds a BS in Biology from DePaul University. Dr. Sorrentino has expertise in general cardiology, hypertension, echocardiography, and peripheral vascular disease. His research has been published in notable journals such as The Lancet and Neurosurgery, with significant citations. He has received several certifications for CMS Meaningful Use and awards for patient satisfaction and medical residents teaching from the Department of Medicine.
Education & Training
University of ChicagoFellowship, Cardiovascular Disease, 1987 - 1991
University of ChicagoResidency, Internal Medicine, 1984 - 1987
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1984
DePaul University, Chicago, IllinoisBS, Biology, Summa Cum Laude, 1980
Certifications & Licensure
IL State Medical License 1985 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory - Core EMR, Epic Systems Corporation, 2013-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Inpatient 2014 Certified EHR Suite, Epic Systems Corporation, 2013-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2013-2017
Publications & Presentations
PubMed
- Recurrent Symptomatic Hemorrhage in Cerebral Cavernous Malformations After Discontinuation of Atorvastatin or Placebo.Bader Ali, Robert Shenkar, Justine Lee, Roberto J Alcazar-Felix, Richard E Thompson
Journal of the American Heart Association. 2026-02-03 - 5 citationsSafety and efficacy of atorvastatin for rebleeding in cerebral cavernous malformations (AT CASH EPOC): a phase 1/2a, randomised placebo-controlled trial.Issam A Awad, Roberto J Alcazar-Felix, Agnieszka Stadnik, Serena Kinkade, Aditya Jhaveri
The Lancet. Neurology. 2025-04-01 - The Bucksbaum Institute for Clinical Excellence and the Doctor-Patient Relationship: Origins, Programs, and Future Directions.Matthew Sorrentino, Joni Krapec, Adam S Cifu, Angela Pace-Moody, Mark Siegler
Academic Medicine. 2023-06-01
Journal Articles
- Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) TrialAmy L Akers, Kevin J Whitehead, Gregory A Christoforidis, Daniel F Hanley, Kelly D Flemming, Sean P Polster, James K Liao, Matthew Sorrentino, Cornelia Lee, Issam A Aw..., Neurosurgery
- Short vs long-term DAPT after stent implantation Commentary on: Gargiulo G et al Short term versus long term dual antiplatelet therapy after implantation of drug eluti...Sorrentino M, BMJ November, 1/1/2016
- Patient perceptions of care as influenced by a large institutional pharmacogenomic implementation programMcKillip RP, Borden BA, Galecki P, Ham SA, Patrick-Miller L, Hall JP, Hussain S, Danahey K, Siegler M, Sorrentino MJ, Sacro Y, Davis AM, Rubin DT, Lipstreuer K, Polons..., Clin Pharmacol Ther, 1/1/2016
Books/Book Chapters
Abstracts/Posters
- Level of education and type of insurance but not race predict control of hypertension in a diverse, high-risk population: The University of Chicago Study of hypertensi...Devore A, Blankstein R, Arnsdorf M, Bakris G, Sorrentino M, AHA QOC meeting, 1/1/2008
- Induction of hemodynamically significant left ventricular outflow tract obstruction in hypertensive hypertrophic cardiomyopathy during dobutamine stress echocardiography.Sorrentino MJ, Marcus R, Korcarz C, Weinert L, Bednarz J, Balasia B, Lang RM, J Amer Coll Cardiol, 1/1/1993
- Left ventricular mechanics of hyperkinetic cardiac function in hypertensionSorrentino M, Murphy M, Weinert L, Bednarz J, Gretler D, Marcus R, Circ, 1/1/1993
Lectures
- 2013 Master Medical Update for the Primary Care PhysicianAmerican Physician Institute for Advanced Professional Studies, Orlando, Florida - 10/11/2013
- 2013 Master Medical Update for the Primary Care PhysicianAmerican Physician Institute for Advanced Professional Studies, Orlando, Florida - 10/11/2013
- 16th Annual Primary Care Update - Session 1Continuing Medical Education Institute, Inc, Marco Island, Florida - 3/18/2013
Other
- Redefining Hypertension — Assessing the New Blood-Pressure GuidelinesMatthew Sorrentino, MD, The New England Journal of Medicine
https://www.doximity.com/articles/2591b462-6ead-4a72-8e1e-2a6949a78b9a
UpToDate, Wolters Kluwer Health - 2012-11-02 - Review of, Hansen BC, Bray GA. The Metabolic Syndrome: Epidemiology, Clinical Treatment, and Underlying Mechanisms. Doody’s Review Service (on-line)Sorrentino M
http://www.doody.com
1/1/2008 - Review of, Krentz AJ, Wong ND. Metabolic syndrome and cardiovascular disease, Doody’s Review Service (on-line).Sorrentino MJ.
http://www.doody.com
1/1/2007
Press Mentions
Appropriate Use CriteriaMarch 1st, 2019
Trump Now in Obese Range but in ‘Good Overall Health’February 15th, 2019
Trump Puts on a Few Pounds, Enters Obese Range: Medical ReportFebruary 14th, 2019
Professional Memberships
- Fellow
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