MelanieAWellingtonMD

PubMed

• 6 citations
  Use of In Vivo Imaging to Screen for Morphogenesis Phenotypes in Candida albicans Mutant Strains During Active Infection in a Mammalian Host.
  Rohan S Wakade, Damian J Krysan, Melanie Wellington> ;Journal of Visualized Experiments. 2022 Oct 12
• Association between job role and coronavirus disease 2019 (COVID-19) among healthcare personnel, Iowa, 2021.
  Takaaki Kobayashi, Alexandra Trannel, John Heinemann, Alexandre R Marra, William Etienne, Oluchi J Abosi, Stephanie Holley, Angelique Dains, Kyle E Jenn, Holly Meacham...> ;Antimicrobial Stewardship & Healthcare Epidemiology. 2022 Jan 1
• Blood culture practices in patients with a central line at an academic medical center-Iowa, 2020.
  Elias Kovoor, Takaaki Kobayashi, Lorinda L Sheeler, Alexandra Trannel, William Etienne, Oluchi Abosi, Stephanie Holley, Angelique Dains, Kyle E Jenn, Holly Meacham, Be...> ;Antimicrobial Stewardship & Healthcare Epidemiology. 2022 Jan 1
• 15 citations
  Coronavirus Disease 2019 Serial Testing Among Hospitalized Patients in a Midwest Tertiary Medical Center, July-September 2020.
  Takaaki Kobayashi, Alexandra Trannel, Stephanie Holley, Mohammed Alsuhaibani, Oluchi Abosi, Kyle E Jenn, Holly Meacham, Lorinda Sheeler, William Etienne, Angelique Dai...> ;Clinical Infectious Diseases. 2021 Nov 2
• 2 citations
  Molecular epidemiology of large coronavirus disease 2019 (COVID-19) clusters before and after the implementation of routine serial testing at an academic medical cente...
  M. Ortiz, Takaaki Kobayashi, Katherine L Imborek, Mohammed Alsuhaibani, Stephanie Holley, Alexandra Trannel, Alexandre R Marra, William Etienne, Kyle E Jenn, Oluchi Ab...> ;Infection Control and Hospital Epidemiology. 2021 Jun 24
• 13 citations
  Intravital Imaging of Candida albicans Identifies Differential In Vitro and In Vivo Filamentation Phenotypes for Transcription Factor Deletion Mutants.
  Rohan S. Wakade, manning huang, Aaron P. Mitchell, Melanie Wellington, Damian J. Krysan> ;Msphere. 2021 Jun 23
• Suspected COVID-19 Reinfections at a Tertiary Care Center, Iowa, 2020
  Takaaki Kobayashi, M. Ortiz, Katherine L Imborek, Mohammed Alsuhaibani, Stephanie Holley, Alexandra Trannel, Alexandre R Marra, William Etienne, Kyle E Jenn, Oluchi Ab...> ;Open Forum Infectious Diseases. 2021 Apr 14
• 10 citations
  Host Carbon Dioxide Concentration Is an Independent Stress for Cryptococcus neoformans That Affects Virulence and Antifungal Susceptibility.
  Damian J. Krysan, Bing Zhai, Sarah R Beattie, Kara M. Misel, Melanie Wellington, Xiaorong Lin> ;Mbio. 2019 Jul 2
• 35 citations
  A Genome-Wide Screen of Deletion Mutants in the Filamentous Saccharomyces cerevisiae Background Identifies Ergosterol as a Direct Trigger of Macrophage Pyroptosis
  Kristy Koselny, Nebibe Mutlu, Annabel Y. Minard, Anuj Kumar, Damian J. Krysan, Melanie Wellington> ;Mbio. 2018 Sep 5
• 50 citations
  High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis.
  Teresa R. O’Meara, Kwamaa Duah, Cynthia X. Guo, Michelle E. Maxson, Ryan G. Gaudet, Kristy Koselny, Melanie Wellington, Michael E. Powers, Jessie MacAlpine, Matthew J....> ;Mbio. 2018 Aug 21
• 17 citations
  Systematic Complex Haploinsufficiency-Based Genetic Analysis of Candida albicans Transcription Factors: Tools and Applications to Virulence-Associated Phenotypes.
  Virginia E. Glazier, Thomas Murante, Kristy Koselny, Daniel Murante, Marisol Esqueda, Gina Wall, Melanie Wellington, Chiung Yu Hung, Anuj Kumar, Damian J. Krysan> ;G3. 2018 Apr 1
• 87 citations
  New facets of antifungal therapy
  Ya-Lin Chang, Shang-Jie Yu, Joseph Heitman, Melanie Wellington, Ying-Lien Chen> ;Virulence. 2017 Feb 17
• 56 citations
  The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis.
  Kristy Koselny, Julianne Green, Louis DiDone, Justin P. Halterman, Annette W. Fothergill, Nathan P. Wiederhold, Thomas F. Patterson, Melanie T. Cushion, Chad Rappelye,...> ;Antimicrobial Agents and Chemotherapy. 2016 Dec 1
• 49 citations
  Catching fire: Candida albicans, macrophages, and pyroptosis.
  Damian J. Krysan, Fayyaz S. Sutterwala, Melanie Wellington> ;Plos Pathogens. 2014 Jun 26
• 118 citations
  A Tetraploid Intermediate Precedes Aneuploid Formation in Yeasts Exposed to Fluconazole
  Benjamin D. Harrison, Jordan Hashemi, Maayan Bibi, Rebecca Pulver, Danny Bavli, Yaakov Nahmias, Melanie Wellington, Guillermo Sapiro, Judith Berman> ;Plos Biology. 2014 Mar 18
• 76 citations
  Estrogen Receptor Antagonists Are Anti-Cryptococcal Agents That Directly Bind EF Hand Proteins and Synergize with Fluconazole In Vivo
  Arielle Butts, Kristy Koselny, Yeissa Chabrier-Roselló, Camile P. Semighini, Jessica C.S. Brown, Xuying Wang, Sivakumar Annadurai, Louis DiDone, Julie M. Tabroff, Wayn...> ;Mbio. 2014 Feb 28
• 164 citations
  Candida albicans triggers NLRP3-mediated pyroptosis in macrophages.
  Melanie Wellington, Kristy Koselny, Fayyaz S. Sutterwala, Damian J. Krysan> ;Eukaryotic Cell. 2014 Feb 1
• 67 citations
  A Repurposing Approach Identifies Off-Patent Drugs with Fungicidal Cryptococcal Activity, a Common Structural Chemotype, and Pharmacological Properties Relevant to the...
  Arielle Butts, Louis DiDone, Kristy Koselny, Bonnie K. Baxter, Yeissa Chabrier-Roselló, Melanie Wellington, Damian J. Krysan> ;Eukaryotic Cell. 2013 Feb 1
• 57 citations
  Candida albicans Morphogenesis Is Not Required for Macrophage Interleukin 1β Production
  Melanie Wellington, Kristy Koselny, Damian J. Krysan> ;Mbio. 2012 Dec 26
• 49 citations
  The Spx Regulator Modulates Stress Responses and Virulence in Enterococcus faecalis
  Jessica K. Kajfasz, Jorge E. Mendoza, Anthony O. Gaca, James H. Miller, Kristy Koselny, Marcia Giambiagi-deMarval, Melanie Wellington, Jacqueline Abranches, José A. Lemos> ;Infection and Immunity. 2012 Jul 1
• 12 citations
  Imaging morphogenesis of Candida albicans during infection in a live animal
  Soumya Mitra, Kristy Dolan, Thomas H. Foster, Melanie Wellington> ;Journal of Biomedical Optics. 2010 Jan 1
• 37 citations
  Nitrite reductase NirS is required for type III secretion system expression and virulence in the human monocyte cell line THP-1 by Pseudomonas aeruginosa.
  Nadine E. Van Alst, Melanie Wellington, Virginia L. Clark, Constantine G. Haidaris, Barbara H. Iglewski> ;Infection and Immunity. 2009 Oct 1
• 74 citations
  Antifungal Activity of Tamoxifen: In Vitro and In Vivo Activities and Mechanistic Characterization
  Kristy Dolan, Sara Montgomery, Bradley Buchheit, Louis DiDone, Melanie Wellington, Damian J. Krysan> ;Antimicrobial Agents and Chemotherapy. 2009 Aug 1
• 64 citations
  Live Candida albicans suppresses production of reactive oxygen species in phagocytes.
  Melanie Wellington, Kristy Dolan, Damian J. Krysan> ;Infection and Immunity. 2009 Jan 1
• 11 citations
  Monocyte responses to Candida albicans are enhanced by antibody in cooperation with antibody‐independent pathogen recognition
  Melanie Wellington, Kristy Dolan, Constantine G. Haidaris> ;FEMS Immunology and Medical Microbiology. 2007 Oct 1
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