MichaelRDebaunMDMPH

Pediatric Hematology & Oncology • Nashville, TN

Pediatric Anemia and Red Blood Cell Hematology

Professor, Pediatrics, Vanderbilt University School of Medicine

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Office
1035 14th Ave N
Nashville, TN 37208
Phone+1 615-322-3000

Fax+1 615-936-0605
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Summary

Dr. Michael Debaun is a pediatric hematologist/oncologist in Nashville, TN and is affiliated with multiple hospitals in the area, including Monroe Carell Jr. Childrens Hospital and Vanderbilt University Medical Center. He received his medical degree from Stanford University School of Medicine and has been in practice 30 years. He specializes in pediatric anemia and red blood cell hematology.

Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Pediatric Hematology/Oncology, 1990 - 1993
Washington University/B-JH/SLCH ConsortiumResidency, Pediatrics, 1987 - 1990
Stanford University School of MedicineClass of 1987

Certifications & Licensure

TN State Medical License 2011 - 2026
FL State Medical License 2013 - 2020
MD State Medical License 1992 - 2010
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

Elected Member Institute of Medicine, 2009

Clinical Trials

Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial Start of enrollment: 2004 Dec 01
Completed
Phase 3
Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease Start of enrollment: 2012 Aug 16
Completed
Phase 2
Sickle Cell Disease - Stroke Prevention in Nigeria Trial Start of enrollment: 2013 Apr 24
Completed
Not Applicable
Phase 2 Study of Montelukast for the Treatment of Sickle Cell Anemia Start of enrollment: 2013 Nov 01
Completed
Phase 2
Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial Start of enrollment: 2014 Jun 01
Completed
Phase 1
Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II Start of enrollment: 2016 Jul 19
Completed
Phase 3
Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa Start of enrollment: 2017 Jan 01
Completed
Phase 3
Macrolide Therapy to Improve Forced Expiratory Volume in 1 Second in Adults With Sickle Cell Disease Start of enrollment: 2016 Sep 01
Withdrawn
Phase 1, Phase 2
Epidemiology of Silent and Overt Strokes in Sickle Cell Disease Start of enrollment: 2017 Jun 02
Recruiting
Management of Severe Acute Malnutrition in SCD, in Northern Nigeria Start of enrollment: 2021 Aug 18
Completed
Phase 2
Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507) Start of enrollment: 2017 Oct 03
Active, not recruiting
Phase 2
Roles: Contact
Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease Start of enrollment: 2018 Jul 01
Active, not recruiting
Not Applicable
Roles: Contact
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Publications & Presentations

PubMed

1 citations
Barriers and Facilitators of Premarital Genetic Counseling for Sickle Cell Disease in Northern Nigeria.
Aisha A Galadanci, Jeremie H Estepp, Hamda Khan, Zubaida L Farouk, Yvonne Caroll, Jason Hodges, Sabiu Yarima, Umma A Ibrahim, Ibrahim M Idris, Awwal Gambo, Nafiu Hussa...> ;Journal of Pediatric Hematology/oncology. 2023 Aug 1
Toward Automated Detection of Silent Cerebral Infarcts in Children and Young Adults With Sickle Cell Anemia.
Yasheng Chen, Yan Wang, Chia-Ling Phuah, Kristin P Guilliams, Slim Fellah, Martin N Reis, Michael M Binkley, Hongyu An, Jin-Moo Lee, Robert C McKinstry, Lori C Jordan,...> ;Stroke. 2023 Aug 1
2 citations
Most adults with severe HbSC disease are not treated with hydroxyurea.
William Kwesi Ghunney, Eugenia Vicky Asare, John Benaiah Ayete-Nyampong, Samuel Antwi Oppong, Mark Rodeghier, Michael R DeBaun, Edeghonghon Olayemi> ;Blood Advances. 2023 Jul 11
1 citations
Acute pain episodes, acute chest syndrome, and pulmonary thromboembolism in pregnancy.
Eugenia Vicky Asare, Michael R DeBaun, Edeghonghon Olayemi, Theodore Boafor, Samuel A Oppong> ;Hematology. American Society of Hematology. Education Program. 2022 Dec 9
9 citations
Epidemiology and treatment of priapism in sickle cell disease.
Ibrahim M Idris, Arthur L Burnett, Michael R DeBaun> ;Hematology. American Society of Hematology. Education Program. 2022 Dec 9
2 citations
Underweight children older than 5 years with sickle cell anemia are at risk for early mortality in a low-resource setting.
Lauren J Klein, Shehu Umar Abdullahi, Safiya Gambo, Virginia A Stallings, Sari Acra, Mark Rodeghier, Michael R DeBaun> ;Blood Advances. 2023 Jun 13
Creating an automated contemporaneous cohort in sickle cell anemia to predict survival after disease-modifying therapy.
Robert M Cronin, Kristin Wuichet, Djamila L Ghafuri, Brock Hodges, Maya Chopra, Jing He, Xinnan Niu, Adetola A Kassim, Karina Wilkerson, Mark Rodeghier, Michael R DeBaun> ;Blood Advances. 2023 Aug 8
11 citations
Hydroxyurea for secondary stroke prevention in children with sickle cell anemia in Nigeria: a randomized controlled trial.
Shehu U Abdullahi, Surayya Sunusi, Mohammed Sani Abba, Saifuddeen Sani, Hauwau Aminu Inuwa, Safiya Gambo, Awwal Gambo, Bilya Musa, Brittany V Covert Greene, Adetola A ...> ;Blood. 2023 Feb 23
2 citations
Effect of Blood Transfusion on Cerebral Hemodynamics and Vascular Topology Described by Computational Fluid Dynamics in Sickle Cell Disease Patients.
Russell P Sawyer, Sirjana Pun, Kristine A Karkoska, Cherita A Clendinen, Michael R DeBaun, Ephraim Gutmark, Riccardo Barrile, Hyacinth I Hyacinth> ;Brain Sciences. 2022 Oct 18
1 citations
Altered VWF:ADAMTS13 homeostasis is a target for therapeutic intervention in sickle cell disease.
Shruti Chaturvedi, Michael R DeBaun> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Oct 4
Sickle Cell Disease and Gene Therapy - Patient and Physician Perspectives.
Michael DeBaun, Matthew Heeney, Terry Jackson, Dan Longo, Melesa Love, Trinity Love, Phillip Okwo, Alexis Thompson, Cassandra Trimnell, Teonna Woolford> ;The New England Journal of Medicine. 2022 Sep 29
Sexual violence as a precipitator of chronic pain in young adults with sickle cell disease.
Maya Chopra, Jeannie Byrd, Kristin Wuichet, Michael R DeBaun> ;Blood Advances. 2022 Aug 23
1 citations
Incidence and predictors of priapism events in sickle cell anemia: a diary-based analysis.
Ibrahim M Idris, Akib Abba, Jamil A Galadanci, Sani A Aji, Atiku U Jibrilla, Mark Rodeghier, Adetola Kassim, Arthur L Burnett, Michael R DeBaun> ;Blood Advances. 2022 Oct 25
2 citations
Primary Prevention of Stroke in Children With Sickle Cell Anemia in Nigeria: Protocol for a Mixed Methods Implementation Study in a Community Hospital.
Halima Bello-Manga, Lawal Haliru, Kudrat Abdulkareem Ahmed, Abdulkadir Musa Tabari, Bilkisu Usman Farouk, Gloria Yimi Bahago, Aisha Shuaibu Kazaure, Abdulrasheed Sani ...> ;JMIR Research Protocols. 2022 Jun 13
3 citations
Long-Term Health Effects of Curative Therapies on Heart, Lungs, and Kidneys for Individuals with Sickle Cell Disease Compared to Those with Hematologic Malignancies.
Courtney D Fitzhugh, Emmanuel J Volanakis, Ombeni Idassi, Josh A Duberman, Michael R DeBaun, Debra L Friedman> ;Journal of Clinical Medicine. 2022 May 31
6 citations
Sustainability of low maternal mortality in pregnant women with SCD in a low-resource setting.
Alim Swarray-Deen, Eugenia V Asare, Ruth Ayettey Brew, John Benaiah Ayete-Nyampong, Yvonne Dei-Adomakoh, Edeghonghon Olayemi, Enoch Mensah, Yvonne Osei-Bonsu, Selina C...> ;Blood Advances. 2022 Apr 12
2 citations
Annual decline in lung function in adults with sickle cell disease is similar to that observed in adults with cystic fibrosis.
Brock Hodges, Zalaya Ivy, Robert M Cronin, Mark Rodeghier, Michael R DeBaun, Shaina M Willen> ;Blood Advances. 2022 Mar 22
5 citations
Translating research to usual care of children with sickle cell disease in Northern Nigeria: lessons learned from the SPRING Trial Team.
Halima Bello-Manga, Lawal Haliru, Abdulkadir M Tabari, Bilkisu Farouk, Aisha Suleiman, Gloria Y Bahago, Abdulrasheed M Sani, Ana A Bauman, Michael R DeBaun, Allison A ...> ;BMC Research Notes. 2022 Jan 4
PRIMARY STROKE PREVENTION IN CHILDREN WITH SICKLE CELL ANEMIA LIVING IN AFRICA: THE FALSE CHOICE BETWEEN PATIENT-ORIENTED RESEARCH AND HUMANITARIAN SERVICE-PART II.
Michael R Debaun> ;Transactions of the American Clinical and Climatological Association. 2022 Jan 1
31 citations
Hydroxyurea for primary stroke prevention in children with sickle cell anaemia in Nigeria (SPRING): a double-blind, multicentre, randomised, phase 3 trial.
Shehu U Abdullahi, Binta W Jibir, Halima Bello-Manga, Safiya Gambo, Hauwa Inuwa, Aliyu G Tijjani, Nura Idris, Aisha Galadanci, Mustapha S Hikima, Najibah Galadanci, Aw...> ;The Lancet. Haematology. 2022 Jan 1
2 citations
Correction: The american pediatric society and society for pediatric research joint statement against racism and social injustice.
Abman, S., Armstrong, S., Baker, S., Bogue, C., Carlo, W., Chalak, L., Daniels, S., Davis, S., Debaun, M., Fike, C., Frazer, L., Gibson, K., Gill, M., Glass, H., Gordo...> ;Pediatric Research. 2022 Jan 1
2 citations
Capacity Building for Primary Stroke Prevention Teams in Children Living With Sickle Cell Anemia in Africa
Djamila L. Ghafuri, Brittany Covert Greene, Bilya Sani Musa, Awwal Gambo, Abdulrasheed Sani, Shehu U. Abdullahi, Binta J. Wudil, Halima Bello-Manga, Safiya Gambo, Mati...> ;Pediatric Neurology. 2021 Dec 1
2 citations
Economic evaluation of regular transfusions for cerebral infarct recurrence in the Silent Cerebral Infarct Transfusion Trial.
Peter Hsu, Chyongchiou J Lin, Mark Rodeghier, Michael R. DeBaun, Robert M. Cronin> ;Blood Advances. 2021 Oct 4
40 citations
Leukemia after gene therapy for sickle cell disease: insertional mutagenesis, busulfan, both, or neither.
Richard J. Jones, Michael R. DeBaun> ;Blood. 2021 Sep 16
17 citations
Academic Medicine's Journey Toward Racial Equity Must Be Grounded in History: Recommendations for Becoming an Antiracist Academic Medical Center.
Consuelo H. Wilkins, Mamie Williams, Karampreet Kaur, Michael R. DeBaun> ;Academic Medicine. 2021 Aug 24
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Journal Articles

Silent Infarcts in Sickle Cell Anemia Occur in the Borderzone Region and Are Associated with Low Cerebral Blood Flow
Lori C Jordan, Andria L Ford, Melanie E Fields, Robert C McKinstry, Michael R DeBaun, Blood
Pregnancy Outcomes in Women with Sickle‐Cell Disease in Low and High Income Countries: A Systematic Review and Meta‐Analysis
Michael R DeBaun, M H Aliyu, M G Tuuli, BJOG: An International Journal of Obstetrics & Gynaecology

Abstracts/Posters

Sickle Cell Disease Post-Transplant Care Challenges in Nigeria: Systematic Institutional Neglect of Medical Tourism
Michael R. DeBaun, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Decline in Forced Expiratory Volume in 1 Second in Older Adults with Sickle Cell Disease Is Similar to Adults with Cystic Fibrosis
Michael R. DeBaun, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
High Levels of Peripheral Vasoconstriction Detected By Polysomnography Predict More Acute Severe Pain Episodes in Children with Sickle Cell Anemia
Michael R. DeBaun, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Reduced Intensity Conditioning for Haploidentical Bone Marrow Transplantation in Patients with Symptomatic Sickle Cell Disease: BMT CTN Protocol 1507
Michael R. DeBaun, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Cross Sectional Survey of Priapism and Sexual Dysfunction in 353 Men with Sickle Cell Disease
Michael R. DeBaun, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
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Lectures

Pediatric Clinical Non-Malignant Hematology
61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
Pediatric Clinical Non-Malignant Hematology
61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
ASH Clinical Practice Guidelines on Sickle Cell Disease
60th American Society of Hematology Annual Meeting - 12/2/2018
Special Education Session on ASH Clinical Practice Guidelines on Sickle Cell Disease
60th American Society of Hematology Annual Meeting - 12/1/2018
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Other

Acute chest syndrome in adults with sickle cell disease
DeBaun MR, Field JJ
http://www.uptodate.com/contents/acute-chest-syndrome-in-adults-with-sickle-cell-disease
UpToDate, Wolters Kluwer Health - 2013-04-12
Acute pain management in adults with sickle cell disease
DeBaun MR, Vichinsky EP
http://www.uptodate.com/contents/acute-pain-management-in-adults-with-sickle-cell-disease
UpToDate, Wolters Kluwer Health - 2012-05-01
Overview of the management of sickle cell disease
DeBaun MR, Vichinsky EP, Field JJ
http://www.uptodate.com/contents/overview-of-the-management-of-sickle-cell-disease
UpToDate, Wolters Kluwer Health - 2013-02-21
Diagnosis and management of priapism in sickle cell disease
DeBaun MR, Field JJ, Vemulakonda VM
http://www.uptodate.com/contents/diagnosis-and-management-of-priapism-in-sickle-cell-disease
UpToDate, Wolters Kluwer Health - 2012-04-10
Hepatic manifestations of sickle cell disease
DeBaun MR, Banerjee S
http://www.uptodate.com/contents/hepatic-manifestations-of-sickle-cell-disease
UpToDate, Wolters Kluwer Health - 2012-04-24
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Press Mentions

Easing the Toll of Sickle Cell Disease in ChildbirthJanuary 2nd, 2017
Vanderbilt Establishes Recruitment Innovation Center to Increase Enrollment of Minorities, Women and Older Adults in Clinical TrialsJuly 5th, 2016
Does Our Healthcare System Abandon Adult Sickle Cell Patients?March 22nd, 2016
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Grant Support

Hydroxyurea To Prevent CNS Complications Of Sickle Cell Disease In ChildrenNational Heart, Lung, And Blood Institute2011
Asthma And Nocturnal Hypoxemia In Sickle Cell Anemia IINational Heart, Lung, And Blood Institute2011
Asthma And Nocturnal Hypoxemia In Sickle Cell Anemia IINational Heart, Lung, And Blood Institute2010
Silent Cerebral Infarct Multi-Center Clinical TrialNational Institute Of Neurological Disorders And Stroke2003–2010
2009 Clinical Research Training Institute Summer WorkshopNational Heart, Lung, And Blood Institute2009
Asthma And Nocturnal Hypoxemia In Sickle Cell AnemiaNational Heart, Lung, And Blood Institute2005–2008
Asthma And Nocturnal Hypoxemia In Sickle Cell AnemiaNational Center For Research Resources2007
Screening And Treatment Of Silent Infarcts For Children With Sickle Cell DISENational Center For Research Resources2005–2006
Importance Of Hemodynamic Factors In The Prognosis Of Stroke In Sickle CellNational Center For Research Resources2005–2006
Importance Of Hemodynamic Factors In The Prognosis Of Stroke In Patient With SCDNational Center For Research Resources2005–2006
Increasing Blood And Cord Blood Donation In BlacksNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2006
Feasibility, Safety And Short-Term Efficacy Of Prolonged Ganciclovir ProphylaxisNational Center For Research Resources2004–2005
Pediatric Oncology GroupNational Cancer Institute1997–1999