MichaelMiksaMDPhD

PubMed

• Adverse Tracheal Intubation Events in Critically Ill Underweight and Obese Children: Retrospective Study of the National Emergency Airway for Children Registry (2013-2...
  Glater, L. B., Gladen, K., Tellez, D., Napolitano, N., Edwards, L., Sanders, R., Kojima, T., Malone, M., Shults, J., Krawiec, C., Ambati, S., McCarthy, R., Branca, A.,...> ;Pediatric Critical Care Medicine. 2024 Feb 1
• 2 citations
  Beyond Survival: Insights From the Phenotyping Sepsis-Induced Multiple Organ Failure Study on the Neurological Impact of Pediatric Sepsis.
  Michael Miksa> ;Pediatric Critical Care Medicine. 2023 Oct 1
• 6 citations
  Implementation of a Critical Care Asthma Pathway in the PICU
  Michael Miksa, Shubhi Kaushik, Gerald Antovert, Sakar Brown, H. Michael Ushay, Chhavi Katyal> ;Critical Care Explorations. 2021 Feb 1
• 11 citations
  Impact of Failure of Noninvasive Ventilation on the Safety of Pediatric Tracheal Intubation.
  Guillaume Emeriaud, Natalie Napolitano, Lee A. Polikoff, John S. Giuliano, Iris Toedt-Pingel, Michael Miksa, Simon Li, Kris Bysani, Deyin D. Hsing, Sholeen Nett, David...> ;Critical Care Medicine. 2020 Oct 1
• 6 citations
  Protein biomarkers for incident deep venous thrombosis in critically ill adolescents: An exploratory study
  Joana A. Tala, Lee A. Polikoff, Matthew Pinto, Simon Li, Erin Trakas, Michael Miksa, Theia Study Investigators, > ;Pediatric Blood & Cancer. 2020 Jan 6
• 6 citations
  Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents.
  Matthew Pinto, Veronika Shabanova, Simon Li, Erin Trakas, Michael Miksa, Lee A. Polikoff, Joana A. Tala, > ;Pediatric Critical Care Medicine. 2019 Oct 1
• 15 citations
  Epidemiology of Lower Extremity Deep Venous Thrombosis in Critically Ill Adolescents
  Edward Vincent S. Faustino, Veronika Shabanova, Matthew Pinto, Simon Li, Erin Trakas, Michael Miksa, Lee A. Polikoff, Massimo Napolitano, Adele Brudnicki, Joana A. Tal...> ;The Journal of Pediatrics. 2018 Oct 1
• 12 citations
  Safety of tracheal intubation in the presence of cardiac disease in paediatric ICUs
  Eleanor Gradidge, Adnan Bakar, David Tellez, Michael Ruppe, Sarah Tallent, Geoffrey L. Bird, Natasha Lavin, Anthony Lee, Vinay M. Nadkarni, Michelle Adu-Darko, Jesse B...> ;Cardiology in the Young. 2018 Apr 25
• 43 citations
  Frequency of Desaturation and Association With Hemodynamic Adverse Events During Tracheal Intubations in PICUs.
  Simon Li, Ting Chang Hsieh, Kyle J Rehder, Sholeen Nett, Pradip Kamat, Natalie Napolitano, David A. Turner, Michelle Adu-Darko, J. Dean Jarvis, Conrad Krawiec, Ashley ...> ;Pediatric Critical Care Medicine. 2018 Jan 1
• 10 citations
  Effect of Location on Tracheal Intubation Safety in Cardiac Disease—Are Cardiac ICUs Safer?
  Eleanor Gradidge, Adnan Bakar, David Tellez, Michael Ruppe, Sarah Tallent, Geoffrey L. Bird, Natasha Lavin, Anthony Lee, Michelle Adu-Darko, Jesse Bain, Katherine Biag...> ;Pediatric Critical Care Medicine. 2017 Dec 1
• 37 citations
  Trend and outcomes of video laryngoscope use across PICUs
  Jocelyn R. Grunwell, Pradip Kamat, Michael Miksa, Ashwin Krishna, Karen Walson, Dennis W. Simon, Conrad Krawiec, Ryan Breuer, Jan Hau Lee, Eleanor Gradidge, Keiko M. T...> ;Pediatric Critical Care Medicine. 2017 Aug 1
• 60 citations
  Relationship Between Adverse Tracheal Intubation Associated Events and PICU Outcomes.
  Margaret M. Parker, Gabrielle Nuthall, Calvin A. Brown, Katherine Biagas, Natalie Napolitano, Lee A. Polikoff, Dennis W. Simon, Michael Miksa, Eleanor Gradidge, Jan Ha...> ;Pediatric Critical Care Medicine. 2017 Apr 1
• 3 citations
  Pulmonary Alveolar Proteinosis in Association with Secondary Hemophagocytic Lymphohistiocytosis
  Jenny Lin, Aliva De, Lisa Figueiredo, Rochelle R. Maxwell, Emily Wasserman, Kelly Adams, Jacqueline Weingarten, Giles J. Peek, Michael Miksa> ;The Journal of Pediatrics. 2017 Apr 1
• 5 citations
  Control of serum glucose concentration in critical illness.
  Sarah B Kandil, Michael Miksa, E. Vincent S. Faustino> ;Current Opinion in Pediatrics. 2013 Jun 1
• 95 citations
  Milk fat globule epidermal growth factor 8 attenuates acute lung injury in mice after intestinal ischemia and reperfusion.
  Tianpen Cui, Michael Miksa, Rongqian Wu, Hidefumi Komura, Mian Zhou, Weifeng Dong, Zhimin Wang, Shinya Higuchi, Wayne W. Chaung, Steven Blau, Corrado P. Marini, Thanja...> ;American Journal of Respiratory and Critical Care Medicine. 2010 Feb 1
• 83 citations
  Immature Dendritic Cell-Derived Exosomes Rescue Septic Animals Via Milk Fat Globule Epidermal Growth Factor VIII
  Michael Miksa, Rongqian Wu, Weifeng Dong, Hidefumi Komura, Dhruv Amin, Youxin Ji, Zhimin Wang, Haichao Wang, Thanjavur S. Ravikumar, Kevin J. Tracey, Ping Wang> ;Journal of Immunology. 2009 Nov 1
• 31 citations
  VX-166: a novel potent small molecule caspase inhibitor as a potential therapy for sepsis
  Peter Weber, Ping Wang, Stephane Maddens, Paul S.H. Wang, Rongqian Wu, Michael Miksa, Weifeng Dong, Michael Mortimore, Golec Julian M C, Peter A. Charlton> ;Critical Care. 2009 Sep 9
• 28 citations
  Ghrelin Hyporesponsiveness Contributes to Age-Related Hyperinflammation in Septic Shock
  Rongqian Wu, Mian Zhou, Weifeng Dong, Youxin Ji, Michael Miksa, Corrado P. Marini, Thanjavur S. Ravikumar, Ping Wang> ;Annals of Surgery. 2009 Jul 1
• 66 citations
  Pivotal Role of the α2A-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Model of Sepsis
  Michael Miksa, Padmalaya Das, Mian Zhou, Rongqian Wu, Weifeng Dong, Youxin Ji, Sanna M. Goyert, Thanjavur S. Ravikumar, Ping Wang> ;Plos One. 2009 May 11
• 214 citations
  A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester
  Michael Miksa, Hidefumi Komura, Rongqian Wu, Kavin G. Shah, Ping Wang> ;Journal of Immunological Methods. 2009 Mar 15
• 59 citations
  Milk fat globule epidermal growth factor-factor VIII is down-regulated in sepsis via the lipopolysaccharide-CD14 pathway.
  Hidefumi Komura, Michael Miksa, Rongqian Wu, Sanna M. Goyert, Ping Wang> ;Journal of Immunology. 2009 Jan 1
• 23 citations
  Downregulation of protein disulfide isomerase in sepsis and its role in tumor necrosis factor-alpha release.
  Mian Zhou, Asha Jacob, Natalie Ho, Michael Miksa, Rongqian Wu, Subir R. Maitra, Ping Wang> ;Critical Care. 2008 Aug 4
• 59 citations
  Ghrelin inhibits sympathetic nervous activity in sepsis.
  Rongqian Wu, Mian Zhou, Padmalaya Das, Weifeng Dong, Youxin Ji, Derek Yang, Michael Miksa, Fangming Zhang, Thanjavur S. Ravikumar, Ping Wang> ;American Journal of Physiology. Endocrinology and Metabolism. 2007 Dec 1
• 89 citations
  Fractalkine-Induced MFG-E8 Leads to Enhanced Apoptotic Cell Clearance by Macrophages
  Michael Miksa, Dhruv Amin, Rongqian Wu, Weifeng Dong, Thanjavur S. Ravikumar, Ping Wang> ;Molecular Medicine. 2007 Nov 1
• 43 citations
  Vasoactive Hormone Adrenomedullin and Its Binding Protein: Anti-Inflammatory Effects by Up-Regulating Peroxisome Proliferator-Activated Receptor-γ
  Michael Miksa, Rongqian Wu, Xiaoxuan Cui, Weifeng Dong, Padmalaya Das, H. Hank Simms, Thanjavur S. Ravikumar, Ping Wang> ;Journal of Immunology. 2007 Nov 1
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Journal Articles

• Control of serum glucose concentration in critical illness  
  Kandil SB, Miksa M, Faustino EV, Curr Opin Pediatr, 1/1/2013
• Milk fat globule epidermal growth factor 8 attenuates acute lung injury in mice after intestinal ischemia and reperfusion  
  Cui T, Miksa M, Wu R, Komura H, Zhou M, Dong W, Wang Z, Higuchi S, Chaung W, Blau SA, Marini CP, Ravikumar TS, Wang P, Am J Respir Crit Care Med, 1/1/2010
• A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester  
  Miksa M, Komura H, Wu R, Shah KG, Wang P, J Immunol Methods, 3/1/2009
• Immature dendritic cell-derived exosomes rescue septic animals via milk fat globule epidermal growth factor-factor VIII  
  Miksa M, Wu R, Dong W, Komura H, Amin D, Ji Y, Wang Z, Wang H, Ravikumar TS, Tracey KJ, Wang P, J Immunol, 1/1/2009
• Ghrelin hyporesponsiveness contributes to age-related hyperinflammation in septic shock  
  Wu R, Zhou M, Dong W, Ji Y, Miksa M, Marini CP, Ravikumar TS, Wang P, Ann Surg, 1/1/2009
• Pivotal role of the alpha(2A)-adrenoceptor in producing inflammation and organ injury in a rat model of sepsis  
  Miksa M, Das P, Zhou M, Wu R, Dong W, Ji Y, Goyert SM, Ravikumar TS, Wang P, PLoS One, 1/1/2009
• VX-166: a novel potent small molecule caspase inhibitor as a potential therapy for sepsis  
  Weber P, Wang P, Maddens S, Wang PSh, Wu R, Miksa M, Dong W, Mortimore M, Golec JM, Charlton P, Crit Care, 1/1/2009
• Milk fat globule epidermal growth factor-factor VIII is down-regulated in sepsis via the lipopolysaccharide-CD14 pathway  
  Komura H, Miksa M, Wu R, Goyert SM, Wang P, J Immunol, 1/1/2008
• Maturation-induced down-regulation of MFG-E8 impairs apoptotic cell clearance and enhances endotoxin response  
  Miksa M, Amin D, Wu R, Jacob A, Zhou M, Dong W, Yang WL, Ravikumar TS, Wang P, Int J Mol Med, 1/1/2008
• Downregulation of protein disulfide isomerase in sepsis and its role in tumor necrosis factor-alpha release  
  Zhou M, Jacob A, Ho N, Miksa M, Wu R, Maitra SR, Wang P, Crit Care, 1/1/2008
• Ghrelin inhibits sympathetic nervous activity in sepsis  
  Wu R., Zhou M., Das P., Dong W., Ji Y., Yang D., Miksa M., Zhang F., Ravikumar T., Wang P, Am J Physiol Endoc M, 1/1/2007
• Vasoactive hormone adrenomedullin and its binding protein: anti-inflammatory effects by upregulating PPAR-gamma  
  Miksa, M., Wu R., Cui X., Dong W., Das P., Simms H.H., Ravikumar T.S., Wang, P, J Immunol, 1/1/2007
• Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages  
  Miksa, M., D. Amin, R. Wu, T. S. Ravikumar, and P. Wang, Mol Med, 1/1/2007
• Dendritic cell-derived exosomes containing milk fat globule epidermal growth factor-factor VIII attenuate proinflammatory responses in sepsis  
  Miksa, M., R. Wu, W. Dong, P. Das, D. Yang, and P. Wang, Shock, 1/1/2006
• Sympathetic excitotoxicity in sepsis: pro-inflammatory priming of macrophages by norepinephrine  
  Miksa, M., R. Wu, M. Zhou, and P. Wang, Front Biosci, 1/1/2005
• Gut-brain interaction in sepsis. E-Letter response to M Badman, J Flier: The Gut and Energy Balance: Visceral Allies in the Obesity Wars  
  Miksa, M, Science, 1/1/2005
• Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain  
  Ikonomidou, C., F. Bosch, M. Miksa, P. Bittigau, J. Vockler, K. Dikranian, T. I. Tenkova, V. Stefovska, L. Turski, and J. W. Olney, Science, 1/1/1999
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Abstracts/Posters

• Fractalkine Induces MFG-E8 and Anti-Inflammatory IL-10 in Sepsis
  M. Miksa, et al., Crit Care Med, 35th Critical Care Congress, 2/6/2008
• Downregulation of milk fat globule EGF-factor VIII in sepsis is CD14-dependent
  Komura, H., M. Miksa, R. Wu, S. Goyert, and P. Wang, Shock, 1/1/2007
• Hyporesponsiveness to ghrelin contributes to aging-related hyperinflammatory state in septic shock
  Wu, R., M. Zhou, W. Dong, Y. Ji, M. Miksa, C. P. Marini, T. S. Ravikumar, and P. Wang, Shock, 1/1/2007
• Erhohte Sterblichkeit von Mausen mit Lactadherinmangel in einer Sepsis: Rolle Verminderter Phagozytose Apoptotischer Zellen
  Miksa, M., D. Dong, R. Wu, T. S. Ravikumar, and P. Wang, Z Geburtshilfe Neonatol, 1/1/2007
• Impaired apoptotic cell clearance in MFG-E8-deficient mice leads to increased mortality in sepsis
  Miksa, M., D. Dong, R. Wu, Y. Ji, T. S. Ravikumar, and P. Wang, Shock, 1/1/2007
• Immature Dendritic Cell Derived Exosomes as Gatekeepers in Sepsis
  M. Miksa, et al., Crit Care Med, 35th Critical Care Congress, 1/6/2006
• Fractalkine increases apoptotic cell clearance by upregulation MFG-E8 in macrophages
  Miksa, M., D. Amin, R. Wu, T. S. Ravikumar, and P. Wang, Shock, 1/1/2006
• Downregulation of protein disulfide isomerase (PDI) in sepsis and its role in proinflammatory cytokine release
  Zhou, M., N. Ho, M. Miksa, R. Wu, Y. Cui, and P. Wang, Shock, 1/1/2006
• VX-166, a novel potent small molecule caspase inhibitor, as a promising new treatment for sepsis
  Weber, P., P. Wang, R. Wu, M. Miksa, W. Dong, G. Ku, D. Dawson, K. Miller, and P. Charlton, Critical Care, 1/1/2006
• Ghrelin inhibits sympathetic nervous activity in sepsis
  Wu, R., M. Zhou, P. Das, W. Dong, Y. Ji, D. Yang, M. Miksa, T. S. Ravikumar, and P. Wang, Shock, 1/1/2006
• Immature dendritic cell (DC)-derived exosomes as gatekeepers in sepsis
  Miksa, M., R. Wu, W. Dong, Y. Ji, T. S. Ravikumar, and P. Wang, Crit Care Med, 12/1/2005
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Lectures

• Proposal of a retrospective study re: “Safety of High-Flow Nasal Cannula Use vs. Non-Invasive Ventilation in infants with Bronchiolitis 
  10/1/2013
• Acute Management in the ER 
  Children's Hospital Boston Satellite Pediatric ER at South Shore Hospital, Weymouth, MA - 1/1/2012
• Case Based Learning for MS2 
  SUNY Downstate, Brooklyn, NY - 1/1/2010
• Annual Scientific Cushing Lectures 
  North Shore-LIJ Medical Center, Manhasset, NY - 1/1/2008
• Hyporesponsiveness to ghrelin contributes to aging-related hyperinflammatory state in septic shock 
  Baltimore, MD - 6/9/2007
• Downregulation of milk fat globule EGF-factor VIII in sepsis is CD14-dependent 
  Baltimore, MD - 6/9/2007
• Impaired apoptotic cell clearance in MFG-E8-deficient mice leads to increased mortality in sepsis 
  Baltimore, MD - 6/9/2007
• Downregulation of Protein Disulfide Isomerase in Sepsis and Its Role in Proinflammatory Cytokine Release 
  Denver, CO - 6/2/2006
• Ghrelin Inhibits Sympathetic Nervous Activity in Sepsis 
  Denver, CO - 6/2/2006
• Fractalkine Induces Apoptotic Cell Clearance By Upregulating MFG-E8 In Macrophages 
  1/1/2006
• A Novel Approach to Inhibit Inflammatory Responses in Sepsis: Modulation of the Sympathetic Nervous System 
  Marco Island, FL - 6/4/2005
• Dendritic Cell-Derived Exosomes Expressing MFG-E8 Attenuate Proinflammatory Responses in Sepsis by Promoting Apoptotic Cell Clearance 
  Nashville, TN - 2/9/2005
• Anti-Inflammatory Effects of Andrenomedullin (AM) and AM Binding Protein-1: an ERK-1/2 MAP Kinase-dependent Pathway 
  Nashville, TN - 2/9/2005
• Anti-Inflammatory Effects of AM and AMBP1 are mediated by PPAR-gamma through the cAMP-Dependent Pathway 
  Halifax, Nova Scotia - 6/5/2004
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Other

• N-Methyl-D-Aspartat-Antagonists induce apoptotic Cell Death in Neonatal Rat Brains 
  Miksa, M
  Medical Faculty Charite, Department of Neuropediatrics . Humboldt-University, Berlin - 1/1/2004