MichaelAPackMD

PubMed

• Model Organisms Help Define the ABCs of Neonatal Cholestasis.
  Michael Pack> ;Gastroenterology. 2021 Apr 15
• A vertebrate model to reveal neural substrates underlying the transitions between conscious and unconscious states
  Victoria M Bedell, Qing C. Meng, Michael Pack, Roderic G. Eckenhoff> ;Scientific Reports. 2020 Sep 25
• Impaired Redox and Protein Homeostasis as Risk Factors and Therapeutic Targets in Toxin-Induced Biliary Atresia
  Xiao Zhao, Kristin Lorent, Diana Escobar-Zarate, Ramakrishnan Rajagopalan, Kathleen M. Loomes, Kevin P. Gillespie, Clementina Mesaros, Michelle A. Estrada, Ian A. Blai...> ;Gastroenterology. 2020 Sep 1
• Protein-elongating mutations in MYH11 are implicated in a dominantly inherited smooth muscle dysmotility syndrome with severe esophageal, gastric, and intestinal disease.
  Melissa A. Gilbert, Laura Schultz-Rogers, Ramakrishnan Rajagopalan, Christopher M. Grochowski, Benjamin J. Wilkins, Sawona Biswas, Laura K. Conlin, Kristin Fiorino, Ra...> ;Human Mutation. 2020 May 1
• 6 citations
  TGFβ and Hippo Pathways Cooperate to Enhance Sarcomagenesis and Metastasis through the Hyaluronan-Mediated Motility Receptor (HMMR)
  Shuai Ye, Ying Liu, Ashley M. Fuller, Rohan Katti, Gabrielle E. Ciotti, Susan Chor, Zahidul Alam, Samir Devalaraja, Kristin Lorent, Kristy L. Weber, Malay Haldar, Mich...> ;Molecular Cancer Research. 2020 Jan 27
• To the Readers, Contributors, Reviewers, and Friends of CMGH.
  Klaus H. Kaestner, Michael Pack> ;Cellular and molecular gastroenterology and hepatology. 2020 Jan 1
• Analysis of stochastic fluctuations in responsiveness is a critical step toward personalized anesthesia.
  Andrew R. McKinstry-Wu, Andrzej Z. Wasilczuk, Benjamin A Harrison, Victoria M Bedell, Mathangi J Sridharan, Jayce J Breig, Michael Pack, Max B. Kelz, Alex Proekt> ;eLife. 2019 Dec 3
• 1 citations
  A New Era of CMGH.
  Klaus H. Kaestner, Michael Pack> ;Cellular and molecular gastroenterology and hepatology. 2019 Sep 10
• Synthesis and Structure–Activity Relationship Study of Biliatresone, a Plant Isoflavonoid That Causes Biliary Atresia
  Michelle A. Estrada, Xiao Zhao, Kristin Lorent, Alyssa Kriegermeier, Seika A. Nagao, Simon Berritt, Rebecca G. Wells, Michael Pack, Jeffrey D. Winkler> ;ACS Medicinal Chemistry Letters. 2018 Jan 11
• Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease
  Yi-An Ko, Huiguang Yi, Chengxiang Qiu, Shizheng Huang, Jihwan Park, Nora Ledo, Anna Köttgen, Hongzhe Li, Daniel J. Rader, Michael Pack, Christopher D. Brown, Katalin S...> ;American Journal of Human Genetics. 2017 Jun 1
• Modeling intestinal disorders using zebrafish
  X Zhao, Michael Pack> ;Methods in Cell Biology. 2017 Jan 1
• The RNA Polymerase III Subunit Polr3b Is Required for the Maintenance of Small Intestinal Crypts in Mice
  Julia E. Kieckhaefer, Sabina Lukovac, Diana Z. Ye, Dolim Lee, Danielle J. Beetler, Michael Pack, Klaus H. Kaestner> ;Cellular and molecular gastroenterology and hepatology. 2016 Nov 1
• The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17
  Orith Waisbourd-Zinman, Hong Koh, Shannon Tsai, Pierre-Marie Lavrut, Christine Dang, Xiao Zhao, Michael Pack, Jeff Cave, Mark Hawes, Kyung A. Koo, John R. Porter, Rebe...> ;Hepatology. 2016 Sep 1
• Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish
  Xiao Zhao, Kristin Lorent, Benjamin J. Wilkins, Dylan M. Marchione, Kevin P. Gillespie, Orith Waisbourd-Zinman, Juhoon So, Kyung A. Koo, Donghun Shin, John R. Porter, ...> ;Hepatology. 2016 Sep 1
• Graded effects of unregulated smooth muscle myosin on intestinal architecture, intestinal motility and vascular function in zebrafish.
  Joshua Abrams, Zev Einhorn, Christoph Seiler, Alan B. Zong, H. Lee Sweeney, Michael Pack> ;Disease Models & Mechanisms. 2016 May 1
• Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids
  Kyung A. Koo, Orith Waisbourd-Zinman, Rebecca G. Wells, Michael Pack, John R. Porter> ;Chemical Research in Toxicology. 2016 Jan 13
• Biliatresone, a Reactive Natural Toxin from Dysphania glomulifera and D. littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone.
  Kyung A. Koo, Kristin Lorent, Weilong Gong, Peter A. Windsor, Stephen J. Whittaker, Michael Pack, Rebecca G. Wells, John R. Porter> ;Chemical Research in Toxicology. 2015 Jul 20
• IBD: Fishing for missing heritability in IBD
  Michael Pack> ;Nature Reviews Gastroenterology & Hepatology. 2015 May 5
• A novel keratin18 promoter that drives reporter gene expression in the intrahepatic and extrahepatic biliary system allows isolation of cell-type specific transcripts ...
  Benjamin J. Wilkins, Weilong Gong, Michael Pack> ;Gene Expression Patterns. 2014 Mar 1
• Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish
  Alexander J. Valvezan, Jian Huang, Christopher J. Lengner, Michael Pack, Peter S. Klein> ;Disease Models & Mechanisms. 2013 Jan 1
• p53-Mediated Biliary Defects Caused by Knockdown of cirh1a, the Zebrafish Homolog of the Gene Responsible for North American Indian Childhood Cirrhosis
  Benjamin J. Wilkins, Kristin Lorent, Randolph P. Matthews, Michael Pack> ;PLOS ONE. 2013 Oct 11
• The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development.
  David R. Rawnsley, Jiping Xiao, John S. Lee, Xi Liu, Patricia Mericko-Ishizuka, Vinayak Kumar, Jie He, Arindam Basu, Min Min Lu, Francis C. Lynn, Michael Pack, Rosa Ga...> ;Journal of Biological Chemistry. 2013 Aug 23
• Zebrafish Models of Human Liver Development and Disease
  Benjamin J. Wilkins, Michael Pack> ;Comprehensive Physiology. 2013 Jul 1
• Visualization of Lipid Metabolism in the Zebrafish Intestine Reveals a Relationship between NPC1L1-Mediated Cholesterol Uptake and Dietary Fatty Acid
  James W. Walters, Jennifer L. Anderson, Robert Bittman, Michael Pack, Steven A. Farber> ;Chemistry & Biology. 2012 Jul 27
• Smooth muscle caldesmon modulates peristalsis in the wild type and non‐innervated zebrafish intestine
  Joshua Abrams, Gangarao Davuluri, Christoph Seiler, Michael Pack> ;Neurogastroenterology and Motility. 2012 Mar 1
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