Michael A Rosenberg MD FHRS, FACC, FAHA

Cardiac Electrophysiology, Cardiovascular Disease Genetics, Clinical Informatics

Associate Professor, Division of Cardiology, University of Colorado School of Medicine; Medical Director of UCH ECG Laboratory, Director of Clinical Sciences Program of the Division of Cardiology

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12401 E. 17th AvenueMail Stop B132Aurora, CO 80045

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Summary

Michael Rosenberg, MD is a Cardiologist based in Aurora, CO, with subspecialties in Cardiac Electrophysiology, Cardiovascular Disease Genetics, and Clinical Informatics. He completed his education and fellowships in Cardiovascular Disease and Clinical Cardiac Electrophysiology at Beth Israel Deaconess Medical Center/Harvard Medical School. Dr. Rosenberg’s employment history includes roles as an Associate Professor at the University of Colorado School of Medicine Anschutz Medical Campus and Physician at Veterans Affairs Boston Healthcare System. He is director of the Clinical Sciences Program for the Division of Cardiology at CU, and medical director of the University of Colorado Hospital ECG Laboratory. His research is focused on development and application of artificial intelligence in clinical decision support, funded primarily by the NIH, with projects centered on drug-induced QT prolongation, rhythm management of atrial fibrillation, and individualized data analysis for clinical decision-making. He has extensive experience in research using the electronic medical record and data from wearable/implanted cardiac devices. His collaboration network includes local clinicians and trainees, and data scientists nationwide, including the CU-Downtown and CU-Boulder campuses, as well as Carnegie Mellon University.

Individualized Data Analysis Organization

Website for the IDAO, which includes discussion of strategies for development and delivery of individualized healthcare for patients and providers.

Education & Training

Broad Institute of Harvard and MITPost-doctoral fellowship, Applied genetics, 2013 - 2016
Beth Israel Deaconess Medical CenterFellowship, Clinical Cardiac Electrophysiology, 2012 - 2013
Beth Israel Deaconess Medical CenterFellowship, Cardiovascular Disease, 2009 - 2012
Beth Israel Deaconess Medical CenterResidency, Internal Medicine, 2004 - 2007
Albert Einstein College of MedicineClass of 2004

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Certifications & Licensure

CO State Medical License 2016 - 2027
MA State Medical License 2006 - 2017
American Board of Internal Medicine Cardiovascular Disease
American Board of Internal Medicine Clinical Cardiac Electrophysiology
American Board of Internal MedicineClinical Cardiac Electrophysiology

Clinical Trials

Genetics of QT Response to Moxifloxacin Start of enrollment: 2013 Oct 01
Terminated
Phase 4
A Registry to Determine the Clinical and Genetic Risk Factors for Torsade De Pointes Start of enrollment: 2013 Oct 01
Terminated

Publications & Presentations

PubMed

Impact of physical activity on atrial fibrillation recurrence following catheter ablation.
Radoslaw J Nabrzyski, Aditya Mantha, Alex Grubb, Dmitriy Kravtsov, William K Cornwell
Journal of Interventional Cardiac Electrophysiology. 2026-06-01
1 citations
HRS scientific statement on artificial intelligence integration framework into clinical electrophysiology workflows.
Antonis A Armoundas, Jennifer N Avari Silva, Tina Baykaner, Neal Bhatia, Nino Isakadze
Heart Rhythm. 2026-04-20
Clinical Predictors of Recurrent Cavotricuspid Isthmus Flutter After Catheter Ablation in Patients With Dextro-Transposition of the Great Arteries.
Alex Grubb, Radoslaw Nabrzyski, Nikhil Shamapant, Francis Zirille, Kishan Padalia
Journal of Cardiovascular Electrophysiology. 2025-11-01

Journal Articles

Retrieval-Augmented Generation for Electrocardiogram-Language Models
Xiaoyu Song, William Han, Tony Chen, Chaojing Duan, Michael A. Rosenberg, Emerson Liu, Ding Zhao, arXiv, 9/30/2025
ECG-Byte: A Tokenizer for End-to-End Generative Electrocardiogram Language Modeling
William Han, Chaojing Duan, Michael A. Rosenberg, Emerson Liu, Ding Zhao, arXiv, 7/29/2025
Signal, Image, or Symbolic: Exploring the Best Input Representation for Electrocardiogram-Language Models Through a Unified Framework
William Han, Chaojing Duan, Zhepeng Cen, Yihang Yao, Xiaoyu Song, Atharva Mhaskar, Dylan Leong, Michael A. Rosenberg, Emerson Liu, Ding Zhao, arXiv, 5/24/2025

Books/Book Chapters

Biomarkers in Disease
Chapter: Circulating fibrosis biomarkers and cardiovascular health: a disease focused approach in heart failure, arrhythmias, sudden cardiac death and atrial fibrillation.
Page 601 - 634Michael RosenbergEditors: Preedy VR and Patel VB.Springer Publishing, New York2016

Lectures

Integration of Artificial Intelligence into Clinical Workflows in Electrophysiology
Colorado Arrhythmia Symposium, Boulder, CO - 9/2025
Clinical Decision Analysis
University of Colorado Computational Biology Course - 5/2025
Leveraging Artificial Intelligence-Enabled ECG Algorithms for Arrhythmia Prediction
Colorado Arrhythmia Symposium, Boulder, CO - 9/2024

Authored Content

Reinforcement Learning for Clinical DecisionsJuly 2023
Evaluation of Machine-Learning ModelsMay 2023
Individualized Risk Stratification of Sudden Cardiac Death: A New Take on Components of the Decision-Making ProcessOctober 2018

Press Mentions

What Your Heart Doctor Wants You to Know About Wearables, Smartwatches and Heart HealthFebruary 20th, 2026
Do Tall Guys Die Younger?September 16th, 2015
‘The Greatest Experiment’: How Is AI Changing Health Care?March 21st, 2026

Grant Support

Phenotypic consequences of lipoprotein(a) in diverse populationsNIH/NHLBI2024–2028
The PATCH of AsclepiusARPA-H2025–2026
AI Optimized Pacing for Heart Failure PatientsUniversity of Colorado AB Nexus Program2024–2026
Development of End-To-End Clinical Decision Support Tools To Prevent Cardiotoxic Drug ResponseUNIVERSITY OF COLORADO DENVER2020–2026
Influence of genetic variation on QT prolongation over the lifecourse and as a cardiotoxic drug responseNIH-NHLBI2018–2022

Committees

Member, Heart Rhythm Society Digital Health Committee 2024 - Present

Research History

Director, Clinical Sciences Program of Division of CardiologyOversee Cardiology Clinical Trials Group conducting over 40 clinical trials with 7 research coordinators; advise and coordinate clinical research support for cardiology faculty in clinical research studies2024 - Present
Director, Individualized Data Analysis OrganizationOrganized research meetings and presentations for application of wearables and novel data sources in clinical care.2017 - 2022
Co-Director, National Genetic Drug-Induced QT Prolongation ConsortiumCollaboration of investigators examining genetic prediction of drug-induced QT prolongation2015 - 2017