MichaelSchlameMD

PubMed

• Cardiolipin prolongs the lifetimes of respiratory proteins in Drosophila flight muscle.
  Mindong Ren, Yang Xu, Colin K L Phoon, Hediye Erdjument-Bromage, Thomas A Neubert, Michael Schlame> ;The Journal of Biological Chemistry. 2023 Oct 1
• 1 citations
  Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity.
  Anjaneyulu Murari, Shauna-Kay Rhooms, Divya Vimal, Kaniz Fatima Binte Hossain, Sanjay Saini, Maximino Villanueva, Michael Schlame, Edward Owusu-Ansah> ;Cell Reports. 2023 Aug 29
• 5 citations
  Genetic modifiers modulate phenotypic expression of tafazzin deficiency in a mouse model of Barth syndrome.
  Suya Wang, Erika Yazawa, Erin M Keating, Neil Mazumdar, Alexander Hauschild, Qing Ma, Haiyan Wu, Yang Xu, Xu Shi, Douglas Strathdee, Robert E Gerszten, Michael Schlame...> ;Human Molecular Genetics. 2023 Jun 5
• Cardiolipin metabolism regulates expression of muscle transcription factor MyoD1 and muscle development.
  Linh Vo, Michael W Schmidtke, Nevton T Da Rosa-Junior, Mindong Ren, Michael Schlame, Miriam L Greenberg> ;The Journal of Biological Chemistry. 2023 Mar 1
• 1 citations
  The critical role of cardiolipin in metazoan differentiation, development, and maturation.
  Melissa Olivar-Villanueva, Mindong Ren, Michael Schlame, Colin K L Phoon> ;Developmental Dynamics. 2023 Jun 1
• 1 citations
  The mystery of mitochondrial plasticity: TMBIM5 integrates metabolic state and proteostasis.
  Mindong Ren, Michael Schlame> ;The EMBO Journal. 2022 Aug 16
• 11 citations
  LPGAT1 controls the stearate/palmitate ratio of phosphatidylethanolamine and phosphatidylcholine in sn-1 specific remodeling.
  Yang Xu, Paighton C Miller, Colin K L Phoon, Mindong Ren, Titli Nargis, Sujith Rajan, M Mahmood Hussain, Michael Schlame> ;The Journal of Biological Chemistry. 2022 Mar 1
• StaR-related lipid transfer-like domain-containing protein CLDP43 affects cardiolipin synthesis and mitochondrial function in Trypanosoma brucei.
  Alessio Loffreda, Michael Schlame, Peter Bütikofer> ;Plos One. 2022 Jan 1
• 6 citations
  Condensed Mitochondria Assemble Into the Acrosomal Matrix During Spermiogenesis.
  Mindong Ren, Yang Xu, Colin K L Phoon, Hediye Erdjument-Bromage, Thomas A Neubert, Sujith Rajan, M Mahmood Hussain, Michael Schlame> ;Frontiers in Cell and Developmental Biology. 2022 Jan 1
• 16 citations
  Cardiolipin remodeling enables protein crowding in the inner mitochondrial membrane.
  Yang Xu, Hediye Erdjument-Bromage, Colin K.L. Phoon, Thomas A. Neubert, Mindong Ren, Michael Schlame> ;The EMBO Journal. 2021 Oct 18
• 2 citations
  A simple mechanistic explanation for Barth syndrome and cardiolipin remodeling.
  Yang Xu, Colin K.L. Phoon, Mindong Ren, Michael Schlame> ;Journal of Inherited Metabolic Disease. 2021 Oct 5
• 13 citations
  Structural basis for potassium transport in prokaryotes by KdpFABC.
  Marie E. Sweet, Casper Larsen, Xihui Zhang, Michael Schlame, Bjørn Panyella Pedersen, David L. Stokes> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Jul 20
• 21 citations
  Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage
  Olga Ilnytska, Kimberly Lai, Kirill Gorshkov, Mark L. Schultz, Bruce Nguyen Tran, Maciej Jeziorek, Thaddeus J. Kunkel, Ruth D. Azaria, Hayley S. McLoughlin, Miriam Wag...> ;The Journal of Biological Chemistry. 2021 Jul 1
• 35 citations
  Increased ROS-Mediated CaMKII Activation Contributes to Calcium Handling Abnormalities and Impaired Contraction in Barth Syndrome
  Xujie Liu, Suya Wang, Xiaoling Guo, Yifei Li, Roza Ogurlu, Fujian Lu, Maksymilian Prondzynski, Sofia de la Serna Buzon, Qing Ma, Donghui Zhang, Gang Wang, Justin Cotto...> ;Circulation. 2021 May 11
• 14 citations
  Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H 2 O 2 production in heart and skeletal muscle mitochondria
  Renata L.S. Goncalves, Michael Schlame, Alexander Bartelt, Martin D. Brand, Gökhan S. Hotamisligil> ;FEBS Letters. 2021 Feb 1
• 22 citations
  Protein crowding in the inner mitochondrial membrane.
  Michael Schlame> ;Biochimica Et Biophysica Acta. Bioenergetics. 2021 Jan 1
• 50 citations
  AAV Gene Therapy Prevents and Reverses Heart Failure in a Murine Knockout Model of Barth Syndrome
  Suya Wang, Yifei Li, Yang Xu, Qing Ma, Zhiqiang Lin, Michael Schlame, Vassilios J. Bezzerides, Douglas Strathdee, William T. Pu> ;Circulation Research. 2020 Apr 10
• 24 citations
  The Function of Tafazzin, a Mitochondrial Phospholipid-Lysophospholipid Acyltransferase.
  Michael Schlame, Yang Xu> ;Journal of Molecular Biology. 2020 Mar 29
• 25 citations
  A Bayesian Analysis to Determine the Prevalence of Barth Syndrome in the Pediatric Population
  Paighton Ciara Miller, Mindong Ren, Michael Schlame, Matthew J. Toth, Colin K.L. Phoon> ;The Journal of Pediatrics. 2020 Feb 1
• 8 citations
  Lipidome-wideC flux analysis: a novel tool to estimate the turnover of lipids in organisms and cultures.
  Michael Schlame, Yang Xu, Hediye Erdjument-Bromage, Thomas A Neubert, Mindong Ren> ;Journal of Lipid Research. 2020 Jan 1
• 6 citations
  Analysis of phospholipid synthesis in mitochondria
  Jorge Montesinos, Estela Area-Gomez, Michael Schlame> ;Methods in Cell Biology. 2020 Jan 1
• 6 citations
  Mitochondrial cristae as insulated transformers of metabolic energy.
  Michael Schlame> ;The EMBO Journal. 2019 Nov 15
• 19 citations
  A critical appraisal of the tafazzin knockdown mouse model of Barth syndrome: what have we learned about pathogenesis and potential treatments?
  Mindong Ren, Paighton Ciara Miller, Michael Schlame, Colin K.L. Phoon> ;American Journal of Physiology. Heart and Circulatory Physiology. 2019 Oct 11
• 25 citations
  Plasmalogen loss caused by remodeling deficiency in mitochondria
  Tomohiro Kimura, Atsuko K. Kimura, Mindong Ren, Vernon Monteiro, Yang Xu, Bob Berno, Michael Schlame, Richard M. Epand> ;Life Science Alliance. 2019 Aug 1
• 24 citations
  Cardiolipin-induced activation of pyruvate dehydrogenase links mitochondrial lipid biosynthesis to TCA cycle function
  Yiran Li, Wenjia Lou, Vaishnavi Raja, Simone Denis, Wenxi Yu, Michael W. Schmidtke, Christian A. Reynolds, Michael Schlame, Riekelt H. Houtkooper, Miriam L. Greenberg> ;The Journal of Biological Chemistry. 2019 Jul 26
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